Peptide Blog

CJC-1295 DAC, also referred to as DAC: GRF or long-acting growth hormone-releasing hormone (GHRH) analog, is a synthetic 29-amino acid peptide derived from the endogenous GHRH sequence.1 It represents a tetrasubstituted analog, incorporating D-Ala, Gln, Ala, and Leu substitutions at positions 2, 8, 15, and 27, respectively. These targeted modifications are intended to support molecular...

Modified GRF 1-29, also referred to as CJC 1295 without DAC or the tetra-substituted GRF 1-29, is a synthetic analogue of growth hormone releasing hormone. It contains the first 29 amino acids of endogenous GHRH, which early studies identified as the minimal sequence capable of retaining the functional characteristics of the full 44 amino acid...

Syn-Coll, also known as Palmitoyl Tripeptide-5 (Palmitoyl-Lys-Val-Lys), is a synthetic tripeptide developed to replicate the biological activity of thrombospondin-1 (TSP-1), an extracellular matrix glycoprotein considered to be involved in cellular signaling and structural maintenance. Research suggests that the design of Syn-Coll was based on short peptide motifs within TSP-1. Specifically, the structure in TSP-1 that...

Decapeptide-12 is a synthetic oligopeptide composed of twelve amino acids (Tyr-Arg-Ser-Aar-Lysd-Tyr-Ser-Ser-Trp-Tyr). It does not appear to mimic any naturally occurring peptide but was designed by researchers with the intent to target specific enzymatic pathways. The peptide has been primarily studied for its inhibitory potential on tyrosinase, an oxidase enzyme that is considered to play a...

Syn-AKE is a synthetic tripeptide engineered to possibly replicate the bioactive function of Waglerin-1, a polypeptide component of the venom of the Malaysian Temple Viper (Tropidolaemus wagleri). Waglerin-1, a 21-amino-acid peptide, appears to exhibit neuromuscular blocking activity by interfering with signal transmission at the neuromuscular junction. Syn-AKE is considered to retain the essential pharmacophore of...

Selank is a synthetic heptapeptide structurally derived from the endogenously occurring tetrapeptide Tuftsin. The peptide sequence comprises the Tuftsin fragment at the N-terminus and a tripeptide Pro-Gly-Pro (PGP) motif at the C-terminal end. The incorporation of the PGP sequence is suggested to influence the peptide’s physiochemical potential in supporting interaction with lipid-rich biological membranes. Selank...

Triptorelin is a synthetic decapeptide and a structural analog of gonadotropin-releasing hormone (GnRH). Reports suggest it was first developed as part of research project on peptide analogs aimed at evaluating peptides that might have the ability to modulate endocrine signaling through the hypothalamic pituitary gonadal (HPG) axis. Structurally, Triptorelin peptide consists of ten amino acids...

Ipamorelin and CJC-1295 blend is a mix of the two synthetic peptides categorized as growth hormone secretagogues (GHSs).This classification refers to compounds that may stimulate the release of growth hormone (GH) through indirect pathways rather than functioning as growth hormone releasing peptides. Ipamorelin is a pentapeptide, also identified as NNC 26-0161, while CJC-1295 is a...

Sermorelin and Ipamorelin are synthetic peptides extensively studied for their potential influence on growth hormone regulation. Sermorelin is a 29-amino acid peptide fragment derived from the endogenous growth hormone-releasing hormone (GHRH), which appears to represent the biologically active N-terminal portion known as Growth Hormone Releasing Factor (1-29) or GRF (1-29). This truncation from the native...