Peptide Blog

Pinealon is a synthetic tripeptide composed of the amino acids L-glutamic acid, L-aspartic acid, and L-arginine (Glu-Asp-Arg)1. It is categorized as a peptide bioregulator because it has been hypothesized to interact directly with cellular DNA and influence gene expression, a property not commonly observed in peptide compounds. Research has associated Pinealon with a range of...

Semaglutide is a synthetic analog of the glucagon-like peptide-1 (GLP-1), an endogenous hormone consisting of 30 amino acids. The primary role of GLP-1 appears to support insulin secretion, lower blood glucose levels, and preserve pancreatic beta cells by stimulating insulin gene transcription. Additionally, it has been posited to delay gastric emptying, leading to appetite suppression....

AOD 9604 is described as a synthetic peptide derived from the C-terminal portion of the native growth hormone (GH). It is specifically derived from the last 15 amino acids (residues 177–191) of GH, with an additional tyrosine residue attached at the N-terminus, making it a peptide composed of 16 amino acids. Moreover, the AOD 9604...

Cardiogen (H-Ala-Glu-Asp-Arg-OH) is a short peptide classified as a bioregulator, primarily recognized for its potential influence on fibroblasts—cells responsible for tissue repair and scar formation. While initial research focused on its possible implications within the context of cardiovascular diseases, recent research suggests that Cardiogen's action may extend beyond the cardiovascular system, indicating potential implications in...

Matrixyl, chemically recognized as palmitoyl pentapeptide-3 (later renamed palmitoyl pentapeptide-4), is a synthetic lipopeptide composed of a fatty acid conjugated to a short chain of amino acids. Containing 5 amino acids (Lys-Thr-Thr-Lys-Ser-OH or KTTKS-OH), this peptide has a fatty acid portion that is speculated to support its lipid solubility, thereby potentially supporting ability to penetrate...

Lipopeptide (aka Palmitoyl hexapeptide-12 or Pal-VGVAPG) is a synthetic peptide derived from a fragment of the protein called elastin. Specifically, its peptide sequence is repeated several times in various forms of elastin, including tropoelastin. The peptide comprises a chain that includes the amino acids valine, glycine, alanine, proline, and glycine in the following sequence: valine-glycine-valine-alanine-proline-glycine...

Kisspeptin-10, an endogenously occurring peptide, is derived from the KISS1 gene. The original 145-amino acid polypeptide undergoes proteolytic cleavage to yield a smaller peptide comprised of 54 amino acids. This 54-amino acid peptide is further processed into Kisspeptin 45-54, commonly referred to as Kisspeptin-10. The KISS1 gene has been identified as a potential suppressor of...

Vialox, also known as Pentapeptide-3v, is a synthetic peptide characterized by the amino acid sequence GPRPA. This molecule is posited to function through the inhibition of neuronal nicotinic acetylcholine receptors located within the postsynaptic membrane of muscle cells. These receptors are deemed responsible for the transmission of signals from nerve cells to muscle cells, which...

Retatrutide, also known by the identifier LY3437943, is a synthetic peptide characterized as a triple receptor agonist, comprising a sequence of 39 amino acids. Designed as an analog to gastric inhibitory polypeptide (GIP), this compound reportedly exhibits additional affinity towards the glucagon-like peptide-1 (GLP-1) receptor and the glucagon (GCG) receptor. These receptors typically bind to...