Peptide Blog

Cardiogen (H-Ala-Glu-Asp-Arg-OH) is a short peptide classified as a bioregulator, primarily recognized for its potential influence on fibroblasts—cells responsible for tissue repair and scar formation. While initial research focused on its possible implications within the context of cardiovascular diseases, recent research suggests that Cardiogen's action may extend beyond the cardiovascular system, indicating potential implications in...

Matrixyl, chemically recognized as palmitoyl pentapeptide-3 (later renamed palmitoyl pentapeptide-4), is a synthetic lipopeptide composed of a fatty acid conjugated to a short chain of amino acids. Containing 5 amino acids (Lys-Thr-Thr-Lys-Ser-OH or KTTKS-OH), this peptide has a fatty acid portion that is speculated to support its lipid solubility, thereby potentially supporting ability to penetrate...

Lipopeptide (aka Palmitoyl hexapeptide-12 or Pal-VGVAPG) is a synthetic peptide derived from a fragment of the protein called elastin. Specifically, its peptide sequence is repeated several times in various forms of elastin, including tropoelastin. The peptide comprises a chain that includes the amino acids valine, glycine, alanine, proline, and glycine in the following sequence: valine-glycine-valine-alanine-proline-glycine...

Kisspeptin-10, an endogenously occurring peptide, is derived from the KISS1 gene. The original 145-amino acid polypeptide undergoes proteolytic cleavage to yield a smaller peptide comprised of 54 amino acids. This 54-amino acid peptide is further processed into Kisspeptin 45-54, commonly referred to as Kisspeptin-10. The KISS1 gene has been identified as a potential suppressor of...

Vialox, also known as Pentapeptide-3v, is a synthetic peptide characterized by the amino acid sequence GPRPA. This molecule is posited to function through the inhibition of neuronal nicotinic acetylcholine receptors located within the postsynaptic membrane of muscle cells. These receptors are deemed responsible for the transmission of signals from nerve cells to muscle cells, which...

Retatrutide, also known by the identifier LY3437943, is a synthetic peptide characterized as a triple receptor agonist, comprising a sequence of 39 amino acids. Designed as an analog to gastric inhibitory polypeptide (GIP), this compound reportedly exhibits additional affinity towards the glucagon-like peptide-1 (GLP-1) receptor and the glucagon (GCG) receptor. These receptors typically bind to...

LL-37 peptide, also recognized as Cathelicidin, appears to be a significant player in the realm of antimicrobial peptides (AMPs), characterized by its cationic nature and composed of 37 amino acids. LL-37 is primarily synthesized in neutrophils, though its presence extends to macrophages and polymorphonuclear leukocytes. This cationic peptide, a member of the antimicrobial peptide (AMP)...

ACE-031 peptide, referred to as ActRIIB-IgG1 peptide, is identified as a myostatin inhibitor. Structurally, it constitutes a fusion compound merging activin receptor type IIB (ACV2RB) with recombinant immunoglobulin IgG1 FC, an antibody variant. Research suggests its solubility and potential to impede circulating myostatin, ostensibly averting the inhibitory action that native ACV2RB receptors are considered to...

In the realm of cellular energetics and metabolic regulation, the peptide AICAR has emerged as a pivotal research compound as it appears to offer compelling prospects for research exploration. Analogous to adenosine monophosphate (AMP), a fundamental nucleotide pivotal in cellular energy metabolism, AICAR (short for 5-aminoimidazole-4-carboxamide ribonucleotide) has garnered attention for its potential in various...