Peptide Blog

Retatrutide is a novel investigational peptide positioned by researchers specializing in the expanding field of multi-agonist agents as an agent relevant to targeted metabolic regulation. The peptide has been classified as a GGG tri-agonist. Retatrutide has been hypothesized to display simultaneous activity at three key receptor systems implicated in energy homeostasis: the glucagon-like peptide-1 receptor...

Kisspeptin-10 (also referred to as “KP-10”) is a short bioactive peptide fragment of the kisspeptin family, originating from proteolytic processing of a 145-amino acid precursor encoded by the KISS1 gene. This gene product is believed to undergo sequential cleavage, yielding several functional fragments, including kisspeptin-54, kisspeptin-14, kisspeptin-13, and the decapeptide Kp-10. Among these, Kp-10 corresponds...

Recent investigations into growth hormone secretagogues (GHSs), growth hormone-releasing peptides (GHRPs), and analogs of growth hormone (hGH) have pointed to their potential in modulating endogenous hormone regulation. Individually and in combination, these agents may potentially influence physiological processes such as lipid mobilization, muscle composition, circadian rhythm modulation, and various systemic functions, including gastrointestinal and cardiovascular...

Follistatin-344 (FST-344) is an endogenous glycoprotein widely distributed across various tissues. It is classified as an autocrine signaling molecule, meaning that scientists consider it to be synthesized and secreted by cells to bind to their own surface receptors, leading to intracellular modifications. Research suggests that Follistatin exists primarily in two isoforms, FST-317 and FST-344, with...

Copper peptides are endogenously occurring complexes formed by binding copper ions (Cu2+) to specific amino acid sequences. Among these, glycyl-L-histidyl-L-lysine (GHK-Cu) is the most extensively studied tripeptide. However, other copper-binding peptides such as DAHK-Cu (Aspartyl-Alanyl-Histidyl-Lysine) and AHK-Cu (Alanine-Histidine-Lysine) have also been identified. These peptides have reportedly been studied for their potential roles in gene expression,...

FOXO4-D-Retro-Inverso (FOXO4-DRI), also called Proxofim peptide, is a synthetic variant of the endogenous FOXO4 protein. This synthetic variant is developed with D-amino acids in place of the endogenously occurring L-amino acids. This modification was made in the hope of supporting stability by reducing susceptibility to proteolytic degradation, thereby increasing the potential to extend a cellular...

Bremelanotide, also known as PT-141, is a synthetic cyclic heptapeptide derived from Melanotan II (MT-II), a synthetic analog of the melanocortin hormone α-melanocyte-stimulating hormone (α-MSH). It was initially investigated for its potential role in addressing hypoactive sexual desire disorder (HSDD) in female research models, as evaluated in Phase IIb clinical trials by qualified researchers. Research...

Pralmorelin, also referred to as Growth Hormone Releasing Peptide-2 (GHRP-2), is a synthetic pentapeptide classified as a growth hormone secretagogue. Structurally analogous to met-enkephalin, it appears to lack opioid activity and instead interacts with the ghrelin/growth hormone secretagogue receptors (GHS-Rs) to stimulate growth hormone (GH) release. Initially developed as a diagnostic agent for assessing GH...

The Tesamorelin & CJC-1295 (Mod GRF 1-29) & Ipamorelin peptide blend represents a combination of synthetic peptides, each with distinct properties that researchers have hypothesized may hold mechanisms for stimulating growth hormone (GH) synthesis and secretion. Although structurally and functionally unique, these peptides appear to share a common focus on modulating the endocrine system's GH...