Peptide Blog

LL-37 peptide, also recognized as Cathelicidin, appears to be a significant player in the realm of antimicrobial peptides (AMPs), characterized by its cationic nature and composed of 37 amino acids. LL-37 is primarily synthesized in neutrophils, though its presence extends to macrophages and polymorphonuclear leukocytes. This cationic peptide, a member of the antimicrobial peptide (AMP)...

ACE-031 peptide, referred to as ActRIIB-IgG1 peptide, is identified as a myostatin inhibitor. Structurally, it constitutes a fusion compound merging activin receptor type IIB (ACV2RB) with recombinant immunoglobulin IgG1 FC, an antibody variant. Research suggests its solubility and potential to impede circulating myostatin, ostensibly averting the inhibitory action that native ACV2RB receptors are considered to...

In the realm of cellular energetics and metabolic regulation, the peptide AICAR has emerged as a pivotal research compound as it appears to offer compelling prospects for research exploration. Analogous to adenosine monophosphate (AMP), a fundamental nucleotide pivotal in cellular energy metabolism, AICAR (short for 5-aminoimidazole-4-carboxamide ribonucleotide) has garnered attention for its potential in various...

Growth Hormone Releasing Peptide-2 (GHRP-2), also known as pralmorelin, stands as a synthetic peptide reportedly designed to mimic the actions of ghrelin, an endogenous peptide considered to be crucial in various physiological processes. Ghrelin, initially discovered in stomach tissues and comprised of 28 amino acids, is considered by scientists to play pivotal roles in regulating...

Nonapeptide-1 peptide initially derived from the yeast Streptomyces clavifer, is currently synthesized using recombinant genetic technology. This peptide since appears to have evolved into a potent inhibitor of melanin formation, as suggested in laboratory studies involving yeast and melanoma (skin cancer) cells. Comprising the amino acids arginine, lysine, methionine, phenylalanine, proline, tryptophan, and valine, Nonapeptide-1...

Ipamorelin and CJC-1295 peptides are classified as growth hormone secretagogues. Ipamorelin is a synthetic pentapeptide, while CJC-1295 is composed of 29 amino acids. Ipamorelin falls within the classification of peptides known as growth hormone secretagogues (GHSs), which are presumed to stimulate the release of growth hormones without being growth hormone releasing peptides themselves. Conversely, researchers...

Protirelin (TRH Thyrotropin) is a synthetic analog peptide of the naturally occurring thyrotropin-releasing hormone (TRH). It comprises three amino acids and is considered by scientists to be released by the brain's hypothalamus region. As such, it is classified as a neuropeptide with potential neuromodulation characteristics. This peptide has also been studied for its potential to...

Thymosin Alpha 1 (Tα1) is a naturally occurring peptide initially isolated from thymus. It comprises 28 amino acids manifesting varied biological potential. These are considered to be highly diverse, including immune response augmentation, strengthening vaccine efficacy, and overcoming chemotherapy-induced and other toxicities. Besides this, the peptide may be relevant in research related to cancers like...

Tesamorelin, Modified GRF 1-29, and Ipamorelin represent a cohort of synthetic peptides with disparate mechanisms, converging on the probable stimulation of growth hormone (GH) synthesis and secretion. Tesamorelin, functioning as a synthetic analogue of growth hormone-releasing hormone (GHRH), appears to exhibit a distinctive potential to elicit the production and release of endogenous growth hormone (GH)....