Peptide Blog

N-Acetyl Semax is a synthetic peptide that is an acetylated version of Semax. Like Semax, it consists of a 4 amino acid fragment (Met-Glu-His-Phe), a common part in the sequence of all melanocortin hormones, such as the adrenocorticotropic hormone (ACTH), and a Pro-Gly-Pro fragment as a stabilizer, that is attached at the C-terminus. The acetylation...

Gonadorelin (GnRH), also known as growth hormone releasing factor (GHRF), somatocrinin, or somatoliberin, is a decapeptide made of 10 amino acids and has the sequence: pyro-Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2. The first amino acid, pyro-Glu, is an unusual form of glutamic acid undergoing cyclization. Scientists consider this cyclization important for Gonadorelin's biological activity, as it may increase its stability...

PE-22-28 is a synthetic peptide analog of spadin, a protein naturally produced in the central nervous system. The sequence of PE-22-28 is based on a fragment of the spadin protein that corresponds to the chain from the 22nd to 28th amino acids of its sequence. More specifically, the amino acid sequence of PE-22-28 is Proline...

Vilon peptide was developed in the 1990s by researchers at the Institute of Immunology in Moscow, Russia. The development of Vilon was part of a broader research program aimed at developing novel immunomodulatory peptides. The researchers were particularly interested in peptides that could regulate the activity of T-cells, a type of white blood cell that plays...

Liraglutide peptide is a synthetic analog of glucagon-like peptide-1 (GLP-1), and it was developed to activate the GLP-1 receptor, increasing insulin secretion, decreasing glucagon secretion, and slowing gastric emptying.  Liraglutide has the following sequence: H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(γ-Glu-palmitoyl)Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-OH. The modification in Liraglutide peptide is the addition of a fatty acid chain (palmitic acid) to the amino acid lysine, in position 26 of...

Modified GRF (1-29) is a peptide hormone that is also known as CJC-1295 without DAC (Drug Affinity Complex). It is a synthetic analog of growth hormone-releasing hormone (GHRH) and is designed to increase natural production of growth hormone. Similarly to other GHRH analogs, it appears to work by binding to the growth hormone-releasing hormone receptor in...

ARA-290 peptide is a small, synthetic peptide is a derivative of erythropoietin (EPO), a hormone that is considered to stimulate the production of red blood cells. However, unlike EPO, ARA-290 does not appear to affect erythropoiesis and has been suggested to exhibit tissue-protective characteristics. In this article, we will explore what ARA-290 peptide is, how...

Sermorelin Acetate, a synthetic peptide, was developed to function as an analog of a naturally occurring hormone called growth hormone-releasing hormone (GHRH). While GHRH has 44 amino acids, Sermorelin peptide is truncated down to 29 amino acids. Sermorelin peptide is also known as the Growth Hormone Releasing Factor (1-29) or GRF (1-29). Sermorelin is the...

Peptides consist of chains of amino acids that may play a crucial role in many biological processes. One such peptide, MOTS-c (mitochondrial ORF of the 12S rRNA type-c), has recently emerged, found in mitochondria, which is considered the powerhouse of the cell. This peptide is encoded in the mitochondrial genome and appears to be able...