Peptide Blog

Gonadorelin (GnRH), also known as growth hormone releasing factor (GHRF), somatocrinin, or somatoliberin, is a decapeptide made of 10 amino acids and has the sequence: pyro-Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2. The first amino acid, pyro-Glu, is an unusual form of glutamic acid undergoing cyclization. Scientists consider this cyclization important for Gonadorelin's biological activity, as it may increase its stability...

PE-22-28 is a synthetic peptide analog of spadin, a protein naturally produced in the central nervous system. The sequence of PE-22-28 is based on a fragment of the spadin protein that corresponds to the chain from the 22nd to 28th amino acids of its sequence. More specifically, the amino acid sequence of PE-22-28 is Proline...

Vilon peptide was developed in the 1990s by researchers at the Institute of Immunology in Moscow, Russia. The development of Vilon was part of a broader research program aimed at developing novel immunomodulatory peptides. The researchers were particularly interested in peptides that could regulate the activity of T-cells, a type of white blood cell that plays...

Liraglutide peptide is a synthetic analog of glucagon-like peptide-1 (GLP-1), and it was developed to activate the GLP-1 receptor, increasing insulin secretion, decreasing glucagon secretion, and slowing gastric emptying.  Liraglutide has the following sequence: H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(γ-Glu-palmitoyl)Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-OH. The modification in Liraglutide peptide is the addition of a fatty acid chain (palmitic acid) to the amino acid lysine, in position 26 of...

Modified GRF (1-29) is a peptide hormone that is also known as CJC-1295 without DAC (Drug Affinity Complex). It is a synthetic analog of growth hormone-releasing hormone (GHRH) and is designed to increase natural production of growth hormone. Similarly to other GHRH analogs, it appears to work by binding to the growth hormone-releasing hormone receptor in...

ARA-290 peptide is a small, synthetic peptide is a derivative of erythropoietin (EPO), a hormone that is considered to stimulate the production of red blood cells. However, unlike EPO, ARA-290 does not appear to affect erythropoiesis and has been suggested to exhibit tissue-protective characteristics. In this article, we will explore what ARA-290 peptide is, how...

Sermorelin Acetate, a synthetic peptide, was developed to function as an analog of a naturally occurring hormone called growth hormone-releasing hormone (GHRH). While GHRH has 44 amino acids, Sermorelin peptide is truncated down to 29 amino acids. Sermorelin peptide is also known as the Growth Hormone Releasing Factor (1-29) or GRF (1-29). Sermorelin is the...

Peptides consist of chains of amino acids that may play a crucial role in many biological processes. One such peptide, MOTS-c (mitochondrial ORF of the 12S rRNA type-c), has recently emerged, found in mitochondria, which is considered the powerhouse of the cell. This peptide is encoded in the mitochondrial genome and appears to be able...

Ipamorelin, also known as NNC 26-0161, is a pentapeptide with the amino acid sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2. Researchers suggest it may induce a peak in growth hormone (GH) synthesis by the pituitary gland via activating the growth hormone secretagogue receptors (GHS-Rs). In this respect, Ipamorelin is classified as a growth hormone secretagogue (GHS). It appears mimic the...