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BPC-157 and Injury Management
In medical research, the recent advancements are majorly focused on the therapeutic approaches for injury management. Researchers are dedicated to finding peptides that have healing potential. Among the different peptides available, scientists focus intensely on BPC 157 because of its healing potential. However, along with these benefits, the BPC 157 peptide is also associated with many side effects.
The following article mainly covers some basic information about BPC 157 peptides.
BPC stands for Body Protection Compound, frequently known by the names Bepecin and PL10. BPC 157 is a stable and synthetic gastric peptide consisting of a pentadecapeptide, i.e., fifteen amino acids.
The BPC peptide has no similarity with any of the natural gastric peptides; thereby, synthetic. Also, it is a BPC taken out from the human gastric juice. However, the stability of BPC 157 is higher than the other peptides, and for a minimum duration of 24 hrs, it can undergo the breakdown of the gastric acid.
BPC is amongst the body’s natural elements, and during various experiments, it has shown the ability to boost the healing processes in animals. In addition to its ability to repair the intestine, BPC has also shown similar results in many other body tissues.
When the healing mechanisms of BPC 157 were studied using different experiments in nonhuman subjects, it was shown that the mechanisms are, to an extent, associated with the Human Growth Hormone.
BPC 157 and Fibroblast Activity
Most connective tissues like tendons, bones, skin, gastric mucose, muscles, etc., have some roaming cells known as Fibroblasts, which initiate the repairing process of the injured tissues by rushing towards the damaged area. They also split and multiply in cases where a higher quantity is required.
The BPC 157 peptide concentrations are also shown to impact the relocation of the fibroblasts, stating that the relocation of more Fibroblasts is achieved with the higher levels of BPC.
The previous studies have shown that the role of collagen fragments is managed by the stimulation of Fibroblasts functioning, which is thereby responsible for the deposition and maintenance of collagen. On Fibroblasts, the impact of GPC 157 has also been revealed by the expression and upregulation of the GH receptor gene, which means that GPC 157 can manipulate the functioning of the DNA.
Evidence has shown that the BPC 157 significantly accelerates fibroblasts’ migration and that fibroblast reproduction increases almost three times after exposure to BPC 157.
As a consequence of the finite supply of blood overall, the recovery of the tendons or the ligaments is not very great. Studies have shown that BPC 157 enhanced the healing of the transversely cut rodents’ Achilles tendon and also resulted in the restoration of the entire integrity of the tendon.
Similar observations were seen in the case of ligament injuries of rodents. The healing was enhanced after exposure to BPC 157, i.e., within three months of the surgical cut, the injury was healed.
BPC 157 Peptide Improves Brain Healing
A positive impact of BPC 157 was displayed on inflammation, hemorrhage, and edema, along with traumatic brain damage and numerous severe brain pathologies resulting from gastrointestinal/ liver lesions or Insulin and NSAID overdose.
BPC 157 Helps in Healing the Blood Vessel Damage
BPC 157 has shown a great potential for angiogenesis, i.e., forming the new blood vessels and guarding the endothelium. It has also been shown to inhibit and reverse the formation of blood clots due to the abdominal aorta’s anastomosis. BPC 157 has been shown to enhance the recovery process by utilizing different vasoactive routes.
Benefits of BPC 157 Peptide
Research has shown BPC 157 acquires major healing properties in numerous tissues like skeletal muscles, bones, tendons, and ligaments.
The impact of BPC 157 on numerous growth factors associated with angiogenesis has also been proposed via different studies on animal subjects.
Various studies also suggest that BPC 157 might be a promoter or a modifier of the body’s natural healing system.
BPC 157 peptide is also associated with other benefits like bone healing, repairing skin damage and muscle injury, and healing the sciatic nerve.
Side Effects of BPC 157
The most common ones exist in 2 forms, i.e., at the site of injection and from the substance itself, and include diarrhea, nausea, fatigue, headache, bowel movement changes, dizziness, fluctuation in weight, and appetite.
Here you can find a guide about how to buy BPC-157 Peptide.
Disclaimer: The products mentioned are not for human or animal consumption. All the information shared in this article is for educational purposes only.
Dr. Usman (BSc, MBBS, MaRCP) completed his studies in medicine at the Royal College of Physicians, London. He is an avid researcher with more than 30 publications in internationally recognized peer-reviewed journals. Dr. Usman has worked as a researcher and a medical consultant for reputable pharmaceutical companies such as Johnson & Johnson and Sanofi.