GHK-Cu (200mg)

(8 customer reviews)


GHK-Cu peptides are Synthesized and Lyophilized in the USA.

Discount per Quantity

Quantity 5 - 910 +
Discount 5%10%
Price $176.70$167.40
Orders over $200 receive:
FREE - 30ml bottle of bacteriostatic water
(Required for reconstitution)
FREE - USPS priority shipping
SKU: GHK-Cu-200mg Category:


GHK-Cu Peptide

GHK-Cu (copper tripeptide) is a naturally occurring plasma peptide. The research impacts of these carrier peptides appear to deliver copper to the skin extracellular matrix to bring about enzymatic wound-healing pathways as well as a possible increase in endogenous collagen and decorin production. GHK-Cu (Copper Peptide) is a tripeptide that scientists assert is naturally present in blood plasma. Scientific studies carried out in different research laboratories worldwide have explored the various biological roles played by tripeptides. GHK-Cu exhibits some potential to influence various biological pathways, including an apparent induction of tissue repair, attraction of immune cells, antioxidant and anti-inflammatory characteristics, activation of collagen and glycosaminoglycan synthesis in skin fibroblasts, and possible promotion of blood vessel growth. Recent studies indicate its potential role in stem cell biology and anti-tumor defense as well.


Molecular Formula: C14H24N6O4

Molecular Weight: 340.38 g/mol

Sequence: Gly-His-LysCu.xHAc

GHK-Cu Peptide Research

Studies have observed that 2% GHK-Cu gel yielded positive results in research models of diabetes when examined in the context of rapid tissue healing. The study findings posit that the peptide appeared to enhance the percentage of ulcer closure from 60.8% to 98.5% and decrease the infection rate from 34% to 7%.[1] 

GHK-Cu and Fibroblasts
Recent research has suggested the molecular mechanisms of the copper-peptide. Pollard et al. posited that GHK-Cu might restore the function of fibroblasts damaged by radiation and thus may help to accelerate cell repair and regenerative processes.[5] The researchers posited that “An early increase in basic fibroblast growth factor and vascular endothelial growth factor production by GHK-Cu-treated irradiated fibroblasts may improve wound healing.” Further studies in the copper peptide GHK-Cu have supported this hypothetical activity of copper peptide GHK-Cu within fibroblasts. Abdulghani et al. noted that a compound containing GHK-Cu appeared to improve collagen in research models of photodamage.[2] The peptide was observed to induce greater results than the control group exposed to a solution of Vitamin C and Retinoic Acid.

Leyden et al. conducted a 12-week study of the possible impacts of GHK-Cu peptide.[3] The study reported significant improvement in skin laxity and a reduction in depth of creases and wrinkles along the skin surface. It appeared to increase skin density and thickness compared to placebo.

Finkley et al. conducted a parallel 12-week study.[4] Experts observed in the study that GHK-Cu compound appeared to have induced dermal Keratinocyte proliferation, as was observed in the histological analysis of biopsies. Copper peptide GHK-Cu and its analogs were observed to potentially stimulate hair follicle development as well. Research is ongoing.

GHK-Cu and Nerve Regeneration
In 2005, Ahmed et al. suggested that tripeptide may also promote nerve regeneration.[6] In the study, GHK-Cu appeared to increase the production rate of nerve growth factor expression of integrins and increased the regeneration rate of myelinated nerve fibers.

GHK-Cu and Stem Cells
In 2009, research findings from a group of researchers from the Seoul National University (Republic of Korea) highlighted that the copper-peptide GHK-Cu appeared to stimulate the proliferation of Keratinocytes and increased the expression of integrins. The researchers also reported the presence of p63 protein in the epidermal stem cells. P63 is considered to be a significant marker of stem cell and anti-senescence protein. The authors concluded that GHK-copper may help restore the proliferative potential of epidermal stem cells and increase their potential to repair tissue.

GHK-Cu and Cancer Cells
In 2010, Hong Y. et al. (Department of Colorectal Surgery, Singapore General Hospital, Singapore) observed the potential of GHK-Cu to reverse the synthesis of a group of genes that play a role in the metastatic spreading of colon cancer.[7] GHK-Cu peptide was observed to yield results within the study conditions at a low concentration. The researchers also concluded that “Gly-His-Lys and securinine could reverse the differential expressions of these genes significantly, suggesting that they have combinatorial … effect on the metastasis-prone [cases].”

Disclaimer: The products mentioned are not intended for human or animal consumption. Research chemicals are intended solely for laboratory experimentation and/or in-vitro testing. Bodily introduction of any sort is strictly prohibited by law. All purchases are limited to licensed researchers and/or qualified professionals. All information shared in this article is for educational purposes only.



  1. Mulder GD, Patt LM, Sanders L, Rosenstock J, Altman MI, Hanley ME, Duncan GW. Enhanced healing of ulcers in patients with diabetes by treatment with glycyl-l-histidyl-l-lysine copper. Wound Repair Regen. 1994 Oct;2(4):259-69. doi: 10.1046/j.1524-475X.1994.20406.x. PMID: 17147644
  2. Abdulghani, AA, Sherr S, Shirin S, Solodkina G, Tapia EM,Gottlieb AB. Effects of creams containing vitamin C, a copper-binding peptide cream and melatonin compared with tretinoin on the ultrastructure of normal skin – A pilot clinical, histologic, and ultrastructural study. Disease Manag Clin Outcomes. 1998;1:136-141
  3. Leyden J, Stephens T, Finkey MB, Appa, Y, Barkovic S, Skin Care Benefits of Copper Peptide Containing Facial Cream. Amer Academy Dermat Meeting, February 2002, Abstract P68, P69
  4. Finkley MB, Appa Y, Bhandarkar S. Copper Peptide and Skin. Cosmeceuticals and Active Cosmetic, 2nd Edition, P. Eisner and H.I. Maibach (Eds.) Marcel Dekker, New York. 2005:549-563
  5. Pollard JD, Quan S, Kang T, Koch RJ. Effects of copper tripeptide on the growth and expression of growth factors by normal and irradiated fibroblasts. Arch Facial Plast Surg. 2005 Jan-Feb;7(1):27-31. doi: 10.1001/archfaci.7.1.27. PMID: 15655171.
  6. Ahmed MR, Basha SH, Gopinath D, Muthusamy R, Jayakumar R. Initial upregulation of growth factors and inflammatory mediators during nerve regeneration in the presence of cell adhesive peptide-incorporated collagen tubes. J Peripher Nerv Syst. 2005 Mar;10(1):17-30. doi: 10.1111/j.1085-9489.2005.10105.x. PMID: 15703015.
  7. Hong Y, Downey T, Eu KW, Koh PK, Cheah PY. A ‘metastasis-prone’ signature for early-stage mismatch-repair proficient sporadic colorectal cancer patients and its implications for possible therapeutics. Clin Exp Metastasis. 2010 Feb;27(2):83-90. doi: 10.1007/s10585-010-9305-4. Epub 2010 Feb 9. PMID: 20143136.
All orders ship same day if placed by 12 PST.
This product is strictly for research/laboratory use only.  Human or animal use and/or consumption is strictly prohibited by law.  Only qualified and licensed professionals should handle these products.  Any information found on Biotech Peptides is strictly for educational purposes only.  Refer to our terms and conditions for more details.

Dr. Usman

Dr. Usman (BSc, MBBS, MaRCP) completed his studies in medicine at the Royal College of Physicians, London. He is an avid researcher with more than 30 publications in internationally recognized peer-reviewed journals. Dr. Usman has worked as a researcher and a medical consultant for reputable pharmaceutical companies such as Johnson & Johnson and Sanofi.

Additional information


Biotech Peptides

8 reviews for GHK-Cu (200mg)

  1. Micthell Maynard

    Packaging could use some work but everything came in pretty good condition.

  2. Allen Cho

    Company is new and fresh. I can tell they have their stuff togther as the customer service is great. The representatives know all about the products and can answer any questions I have had thus far.

  3. Carl Fitzgerald

    I notice they were out of stock of one of the peptides I need for my research a few days before I had to order more. Thankfully they had a restock of it that morning!

  4. Lucy Wong

    Biotech has been my peptide supplier since the beginning of the year. I enjoy their frequent sales and promo codes they send out. Prices are not the cheapest but they’re also not the most expensive!

  5. Daniel Salinas

    Peptides are fantastic!

  6. Scott Gleason

    If you do a lot of research with peptides, I highly recommend Biotech. They have great deals and are willing to work with you on price if you buy in bulk and buy consistently

  7. Joe McKay

    Had a small issue where my peptides were not sent all togther. Just called and requested that all peptides come in one box rather then 2.

  8. Maddy Siomara

    Got my peptide within a day with no cracks or issues.

Add a review