GHRP-6 (10mg)

(22 customer reviews)

$29.00

GHRP-6 peptides are Synthesized and Lyophilized in the USA.

Discount per Quantity

Quantity5 - 910 +
Discount5%10%
Price$27.55$26.10
Orders over $200 receive:
FREE - 30ml bottle of bacteriostatic water
(Required for reconstitution)
FREE - USPS priority shipping
SKU: GHRP-6-10mg Category:

Description

What is the GHRP-6 Peptide?

GHRP-6 peptide is studied for its potential as a powerful stimulant that helps release natural growth hormone (GH) from the anterior pituitary gland. In addition, it may also act as a ghrelin/growth hormone receptor agonist and is amongst the ghrelin analogs developed in recent decades. It has been observed to deliver a positive influence on cardiac muscle cells, scar formation, memory formation, sex motivation, and the neurons associated with Parkinson’s disease. The peptide is orally and sublingually active and moderately to highly specific in its action.

Specifications

Molecular Formula: C46H56N12O6

Molecular Weight: 873.032 g/mol

Sequence: His-D-Trp-Ala-Trp-D-Phe-Lys

PubChem: CID 9919153

CAS Number: 87616-84-0

Reconstitution: Required

Research

GHRP-6 and Memory
Scientists have been investigating the role of physical activity in learning and memory formation. It has been observed that physical activity such as exercise helps to enhance cognitive learning, particularly when it is done immediately following a learning activity. However, the precise mechanism remains unknown. Initially, exercise was thought to help cognition through improved blood circulation in the brain and increased growth hormone production. Studies on rodent models have highlighted how GHRP-6 may help to consolidate newly created memories and transform short-term memories into long-term storage. Significant scientific observations further posit the beneficial role of ghrelin/GHRP-6 in spatial learning tasks. Growth hormone secretagogues such as ghrelin may bring about exercise-induced cognitive improvements. Hence, the role of GH may be possibly indirect and perhaps secondary to these peptides.

GHRP-6 and Brain Tissue Protection
The role of the GHRP-6 peptide in the amelioration of stroke has been studied using appropriate animal models. The timely administration of the peptide appears to protect the brain tissue from reduced blood supply (following a stroke) and may help in recovery from memory lapses due to stroke.[1] At a molecular level, the peptide and its analogs may prevent apoptosis of neurons of the central nervous system which would prevent genetic reprogramming and inflammation.

GHRP-6 Peptide and Parkinson’s
A study conducted in 2018 highlighted the prevalence of ghrelin receptors in substantia nigra, a part of the brain known to get affected in Parkinson’s disease.[2] Patients genetically predisposed to the disease also showed a significant reduction in ghrelin receptors in their substantia nigra. It was observed that genetically modulated rats also exhibit Parkinson’s symptoms when an antagonist is administered. The researchers concluded that “These findings suggest that the down-regulation of GHSRs in SNc-DA neurons induced the initial dysfunction of DA neurons, leading to extrapyramidal disorder under PD.” Therefore, agonists like GHRP-6 may be potentially beneficial in the treatment of Parkinson’s disease. Scientists hypothesize that the peptide associated with receptors present in the substantia nigra decreases neuronal apoptosis and thus may subside or ameliorate the onset of this disease.

GHRP-6 Peptide and Cardiac Issues
The GHRP-6 peptide was observed to inhibit free radical-mediated cytotoxicity of cardiac cells in porcine models.[3] It may be used to develop medicines to protect the viable cardiac tissues from damage after cardiac arrest. Such a medication would be helpful not only in reducing the chances of death but also in overcoming any long-term adverse effects caused by cardiac arrest.

GHRP-6 and Sex Motivation, Mood
Studies on male rats have observed the role of ghrelin receptors in the central nervous system in modulating sexual behavior and motivation. Increased amounts of ghrelin have appeared to stimulate sexual impulses. GHRP-6 and its modified counterpart (which may antagonize the ghrelin receptor) have suggested that ghrelin receptors in specific brain areas may influence sexual and reward-seeking conduct. There is also data to suggest that ghrelin may influence mood as part of its impact on motivation. The peptide and its analogs appear to help improve brain function associated with lifting moods, stress relief, and overcoming depression in murine models.[4] GHRP-6 may therefore have the potential to treat stress, depression, anxiety, and related mood disorders.

GHRP-6 and Scarring, Skin Appearance
GHRP-6 researchers hypothesize the peptide may have to potential to aid in the survival of diverse kinds of cells by decreasing programmed cell death. The peptide is also associated with the CD36 receptor and may help to promote blood vessel growth, particularly in wounds. Experiments with GHRP-6 and rat models also suggest it may be effective in faster wound closure in rats. It appears to help in rapid wound healing and the formation of extracellular matrix proteins such as collagen, promoting the overall correct organization of tissue around a scar and thus reducing the appearance of scar marks. Hypertrophic scars, like keloids, occur due to improper deposition of matrix proteins. Scientists suggest that GHRP-6 may block this aberrant wound healing process, and would be potentially useful for people who delay surgery to avoid such painful after-effects and aesthetic changes. Studies in GHRP-6 have reported minimal to moderate side effects, low oral bioavailability, and excellent subcutaneous bioavailability in murine models of study.[5] The researchers also noted that “Our observation that GHRP-6 intravenous administration proved to be safe in a dose scale-up clinical trial in healthy human volunteers is significantly important.” The dosage (per kg) required in mice does not match up to that required for humans.

References

  1. Subirós N, Pérez-Saad HM, Berlanga JA, Aldana L, García-Illera G, Gibson CL, García-Del-Barco D. Assessment of dose-effect and therapeutic time window in preclinical studies of rhEGF and GHRP-6 coadministration for stroke therapy. Neurol Res. 2016 Mar;38(3):187-95. doi: 10.1179/1743132815Y.0000000089. Epub 2016 Apr 19. PMID: 26311576.
  2. Suda Y, Kuzumaki N, Sone T, Narita M, Tanaka K, Hamada Y, Iwasawa C, Shibasaki M, Maekawa A, Matsuo M, Akamatsu W, Hattori N, Okano H, Narita M. Down-regulation of ghrelin receptors on dopaminergic neurons in the substantia nigra contributes to Parkinson’s disease-like motor dysfunction. Mol Brain. 2018 Feb 20;11(1):6. doi: 10.1186/s13041-018-0349-8. PMID: 29458391; PMCID: PMC5819262.
  3. Berlanga J, Cibrian D, Guevara L, Dominguez H, Alba JS, Seralena A, Guillén G, López-Mola E, López-Saura P, Rodriguez A, Perez B, Garcia D, Vispo NS. Growth-hormone-releasing peptide 6 (GHRP6) prevents oxidant cytotoxicity and reduces myocardial necrosis in a model of acute myocardial infarction. Clin Sci (Lond). 2007 Feb;112(4):241-50. doi: 10.1042/CS20060103. PMID: 16989643.
  4. Huang HJ, Zhu XC, Han QQ, Wang YL, Yue N, Wang J, Yu R, Li B, Wu GC, Liu Q, Yu J. Ghrelin alleviates anxiety- and depression-like behaviors induced by chronic unpredictable mild stress in rodents. Behav Brain Res. 2017 May 30;326:33-43. doi: 10.1016/j.bbr.2017.02.040. Epub 2017 Feb 27. PMID: 28245976.
  5. Berlanga-Acosta J, Abreu-Cruz A, Herrera DGB, Mendoza-Marí Y, Rodríguez-Ulloa A, García-Ojalvo A, Falcón-Cama V, Hernández-Bernal F, Beichen Q, Guillén-Nieto G. Synthetic Growth Hormone-Releasing Peptides (GHRPs): A Historical Appraisal of the Evidences Supporting Their Cytoprotective Effects. Clin Med Insights Cardiol. 2017 Mar 2;11:1179546817694558. doi: 10.1177/1179546817694558. PMID: 28469491; PMCID: PMC5392015.
All orders ship same day if placed by 2pm PST.
This product is strictly for research/laboratory use only.  Human or animal use and/or consumption is strictly prohibited by law.  Only qualified and licensed professionals should handle these products.  Any information found on Biotech Peptides is strictly for educational purposes only.  Refer to our terms and conditions for more details.

Additional information

Brand

Biotech Peptides

22 reviews for GHRP-6 (10mg)

  1. Callum Morton

    Loved this product. Fast delivery and great services.

  2. Asher Carter

    Love the range of products and their results

  3. Yurek V.

    Overall very happy with my experinece

  4. Nick Johnston

    I was given a 20% off code by one of the customer service reps. Much appreciated! Email them if you need help they always assist.

  5. Stephen Lee

    Arrived in 3 days. The peptides come lyophilized, in a dry powder form. Dont forget you need bacteriostatic water to mix I made that mistake the first time.

  6. Krys Lee

    I have been shopping here for a while and I can honestly say this is the absolute best peptide supplier in business

  7. Sawyer Myers

    I honestly never knew that a company can be so nice to its customer. I really feel amazing every single time I order from you guys

  8. Kyle Galvan

    Pretty solid peptide company

  9. Ky Borromeo

    Acabo de hacer mi primer pedido y estoy muy contento de recibirlo.

  10. Gina Lynn

    I wish I could see more stacks on your website. I’ve been researching a while and I’ve seen so many combinations I’d love to see here. I could buy them separately, sure, but they cost so much more than blends

  11. Farah Zeidan

    Finally found my go-to peptide supplier

  12. Kevin W.

    I have ordered from this company many times and my expectations are always met. Just ordered this product and I can’t wait to experiment with it knowing that the products are always top quality.

  13. Jerolyn C.

    I wish you guys had more coupon codes or vouchers for big purchases. It would be a big help for loyal customers such as myself

  14. Ajinkya Josh

    Impressed by how quickly and safley the peptide came. I only did one small order as this was my first purchase. I would order again.

  15. Jane Winters

    All in all, I would recommend them to anyone looking for amazing quality peptides.

  16. R.J Basset

    9/10. One point off for the so so packaging.

  17. Jarrod Dettmer

    No issues with shipment. Had a small hiccup with payment as my card declinded but they called me right away and got it handeled.

  18. moe kester

    Based all the way north in Canada. Happy to report all peptides came in safley! Not only that but I had no issues with customs.

  19. paul t. lewis

    Trustworthy site and amazingly pure peptides!

  20. John Hochman

    Their prices are average and peptides are okay. Good enough to do the job properly and be legitimate peptide as well. Like I said prices are okay, have seen better and have seen worse.

  21. Matty Toczynski

    Good Products

  22. Je Hong

    Shipping was fast and happy there was a fragile sign on the package so carrier is extra careful with it

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