GHRP-2 (10mg)

(26 customer reviews)

$39.00

GHRP-2 peptides are Synthesized and Lyophilized in the USA.

Discount per Quantity

Quantity 5 - 910 +
Discount 5%10%
Price $37.05$35.10
Orders over $200 receive:
FREE - 30ml bottle of bacteriostatic water
(Required for reconstitution)
FREE - USPS priority shipping
SKU: GHRP-2-10mg Category:

Description

GHRP-2 Peptide

GHRP-2, or pralmorelin, (also available in 5mg) is a synthetic growth hormone secretagogue which interacts with the ghrelin/growth hormone secretagogue receptor.  It is a research peptide studied to evaluate growth hormone deficiency as well as secondary adrenal failure. Extensive research has also been performed to evaluate its role in the regulation of muscle development, appetite, the immune system, and sleep cycles.[1]

Specifications

Other Known Titles: Thymosin Beta 4

Molecular Formula: C45H55N9O6

Molecular Weight: 817.9 g/mol

Sequence: H-D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2

GHRP-2 Research

GHRP-2 and Muscle Structure
Research in yaks noted that GHRP-2 peptide appeared to stimulate the growth of muscles in two ways: enhanced protein synthesis and accumulation, and reduced protein degradation.[3] The study suggested that GHRP-2 may help to overcome natural growth limitation that occurs in yaks because of food deprivation, adverse environmental conditions, and disease. The researchers also posited that “GHRP-2 enhanced muscle protein deposition mainly by up-regulating the protein synthesis pathways.” The most significant observation has been the potential action of GHRP-2 in reducing muscle atrophy through repression of atrogin-1 and MuRF1- proteins, which regulate muscle degradation pathways.

GHRP-2 and the Heart
Studies in fetal heart cell culture lines have theorized that GHRP-2 and its analogs (GHRP-1 and GHRP-6) may help to protect cardiac cells by minimizing apoptosis or programmed cell death.[4] The peptide appears to protect cardiac muscles from reduced supply of blood and nutrients, which may ensue a cardiac arrest. Studies on Hexarelin, a GHRP-2 analog, have posited that these peptides associate with a specific receptor.

GHRP-2 and the Immune System
GHRP-2 peptide researchers suggest the peptide may enhance the functions of the thymus, an organ that helps protect and mature certain cells of the immune system, especially the T lymphocytes.[5] T lymphocytes are crucial for adaptive immunity and the physiological capacity to combat complex infections. However, the efficacy of the thymus diminishes, which may induce instances of tissue damage, to diminished immunity. In such cases, GHRP-2 appears to have the potential to rejuvenate the thymus, possibly promoting the number and diversity of T-cells, possibly boosting general immunity.

GHRP-2 and Pain Perception
Researchers initially hypothesized that GHRP-2 may decrease pain associated with osteoarthritis in animal models through the stimulation of growth hormone production and the repair of damaged tissues. However, it has been suggested since that GHRP-2 may induce pain relief prior to tissue repair, which may occur due to an action on opioid receptors. There are four known opioid receptors.[6] Other compounds studied for their impact on opioid receptors appear to typically mediate a universal action on all four receptors. The generic mode of action may create challenges as the receptors may have differential and diverse functions.  GHRP-2 appears to be a selective opioid receptor agonist, binding uniquely to the receptors implicated in pain perception, reward system linking, and sedation.

GHRP-2 and Sleep Cycles
GHRP-2 has been suggested to influence sleep cycles. The peptide may increase the duration of stages 3 and 4 of the sleep cycles by up to 50%, as reported by researchers, as well as potentially improve the duration of REM sleep by approximately 20%.[7] It may further diminish deviation in sleeping patterns from “normal sleep”. Research is ongoing.

Disclaimer: The products mentioned are not intended for human or animal consumption. Research chemicals are intended solely for laboratory experimentation and/or in-vitro testing. Bodily introduction of any sort is strictly prohibited by law. All purchases are limited to licensed researchers and/or qualified professionals. All information shared in this article is for educational purposes only.

 

References

  1. Phung LT, Inoue H, Nou V, Lee HG, Vega RA, Matsunaga N, Hidaka S, Kuwayama H, Hidari H. The effects of growth hormone-releasing peptide-2 (GHRP-2) on the release of growth hormone and growth performance in swine. Domest Anim Endocrinol. 2000 Apr;18(3):279-91. doi: 10.1016/s0739-7240(00)00050-3. PMID: 10793268.
  2. Laferrère B, Abraham C, Russell CD, Bowers CY. Growth hormone releasing peptide-2 (GHRP-2), like ghrelin, increases food intake in healthy men. J Clin Endocrinol Metab. 2005 Feb;90(2):611-4. doi: 10.1210/jc.2004-1719. PMID: 15699539; PMCID: PMC2824650.
  3. Hu R, Wang Z, Peng Q, Zou H, Wang H, Yu X, Jing X, Wang Y, Cao B, Bao S, Zhang W, Zhao S, Ji H, Kong X, Niu Q. Effects of GHRP-2 and Cysteamine Administration on Growth Performance, Somatotropic Axis Hormone and Muscle Protein Deposition in Yaks (Bos grunniens) with Growth Retardation. PLoS One. 2016 Feb 19;11(2):e0149461. doi: 10.1371/journal.pone.0149461. PMID: 26894743; PMCID: PMC4760683.
  4. Titterington JS, Sukhanov S, Higashi Y, Vaughn C, Bowers C, Delafontaine P. Growth hormone-releasing peptide-2 suppresses vascular oxidative stress in ApoE-/- mice but does not reduce atherosclerosis. Endocrinology. 2009 Dec;150(12):5478-87. doi: 10.1210/en.2009-0283. Epub 2009 Oct 9. PMID: 19819949; PMCID: PMC2795722.]
  5. Chao YN, Sun D, Peng YC, Wu YL. Growth Hormone Releasing Peptide-2 Attenuation of Protein Kinase C-Induced Inflammation in Human Ovarian Granulosa Cells. Int J Mol Sci. 2016 Aug 19;17(8):1359. doi: 10.3390/ijms17081359. PMID: 27548147; PMCID: PMC5000754.
  6. Zeng P, Li S, Zheng YH, Liu FY, Wang JL, Zhang DL, Wei J. Ghrelin receptor agonist, GHRP-2, produces antinociceptive effects at the supraspinal level via the opioid receptor in mice. Peptides. 2014 May;55:103-9. doi: 10.1016/j.peptides.2014.02.013. Epub 2014 Mar 4. PMID: 24607724.
  7. Sigalos JT, Pastuszak AW. The Safety and Efficacy of Growth Hormone Secretagogues. Sex Med Rev. 2018 Jan;6(1):45-53. doi: 10.1016/j.sxmr.2017.02.004. Epub 2017 Apr 8. PMID: 28400207; PMCID: PMC5632578.
All orders ship same day if placed by 12 PST.
This product is strictly for research/laboratory use only.  Human or animal use and/or consumption is strictly prohibited by law.  Only qualified and licensed professionals should handle these products.  Any information found on Biotech Peptides is strictly for educational purposes only.  Refer to our terms and conditions for more details.

Additional information

Brand

Biotech Peptides

26 reviews for GHRP-2 (10mg)

  1. Isabella Gelbero

    I am overall pleased with the whole process

  2. Jasper Hall

    The packaging: well packed, clean and sealed. If these three things are off I’d recommend finding another vendor. Given the fragile nature of peptides, I was highly impressed with the level of professionalism when I received my order.

  3. Brian McCready

    I ordered yesterday, and the items were here this morning. The turnaround time is excellent

  4. Joe Moors

    My order got stuck in customs. Took a few weeks to get cleared but I finally received it. Could’ve been smoother but I understand thats out of your control.

  5. Sarah Diaz

    Very professional, they took their time with me and answered any questions I had. They assured me the products will not be damaged and get to me within the next 24 hours. They did. I had worries with the temperature and making sure no product was spoiled or ruined but they all looked good to me.

  6. Cody Raybourn

    Smooth sailing with them, keep it up

  7. Matthew Brugner

    Great turnaround time, good prices, would like to see how they keep up with supplies

  8. Aspen Sanders

    I was really scared to get into peptides at first, but Danni from CS took me under their wing and put all of my fears at ease. Now every time I need any info, I call and they solve it right away

  9. Sherwin Rodriguez

    I find the blog part of the website to be informative and interesting. They’re always short, to the point, and current.

  10. Isreal Revivo

    Amazing product

  11. Erick Smith

    I’ve seen amazing results with this product and I can whoheartedly say it is worth every penny

  12. Erick Smith

    I’ve seen amazing results with this product and I can whoheartedly say it is worth every penny

  13. Jeanne Gee Tran

    Always a pleasure doing business with Biotech

  14. Jon Jiang

    My favorite supplier, always quick to help and never fail at providing quality.

  15. Demitri Yermakov

    Been shopping with them a few months. Everything always checks out. Have had an instance or two where shipping was late but again not something they can control.

  16. Arthur Gibbs

    LOVE THEIR PEPTIDE QUALITY, HAVE NOT COME ACCROSS ONES LIKE THEIRS. MY SUGGESTION WOULD BE TO CREATE GROUP BUNDLES AND DEALS FOR PRODUCTS BOUGHT TOGTHER.

  17. Simon Irving

    Everything is so simple with them. I have seen a bunch of people on other sites struggling to get a response or solve a problem, only receiving an automated message back. With Biotech everything is so easy and drama-free. Totally recommend

  18. Edward Owen

    In my opinion they’re one of the top 3 peptide companies.

  19. ronald jones

    I have been working with this company since they first started and really happy that they have maintained the best customer service and top of the line products.

  20. Caleb Wood

    Have ordered with them multiple times in the last few months. I can report that I have not had any complaints or concerns. Packaging is fine, no breaks or damaged peptides. Bac waters and promotional codes are frequently sent out as well.

  21. john samir

    I like the Bac water they send! Works well!

  22. David Nguyen

    Peptides are great. Research is really taking off and showing results I have not seen before with other company peptides.

  23. Bruce Whitney

    They work well and are the purest I have worked with thus far.

  24. Jesse Saywell

    Not only is their products the best I have ever come across but the way they train their employees is out of this world. Always receive the best service and no long wait for calls or emails. They have well trained staff that that are quick on their feet to solve issues too.

  25. Leo Hoffman

    Blogs are up to date with some valuable information about peptides! I like that it also has a link to the specific peptide as well; Makes it easier to find and purchase.

  26. Brady Basso

    Biotech is in my top 5 suppliers. I Like using a variety of peptide suppliers and they are one of the few I gear towards buying from.

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