GHRP-2 (10mg)

(26 customer reviews)

$29.00

Discount per Quantity

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5 - 95%$27.55
10 +10%$26.10
SKU: GHRP-2-10mg Category:

Description

What is GHRP-2 Peptide?

GHRP-2 (also known as pralmorelin) is a synthetic growth hormone secretagogue that interacts with the ghrelin/growth hormone secretagogue receptor. It was the first growth hormone secretagogue to be introduced commercially, amongst several others. It is a peptide that is now sold as a test peptide to evaluate growth hormone deficiency as well as secondary adrenal failure. GHRP-2 has also been evaluated in stage II clinical trials for the assessment of short stature. Extensive research has also been performed to evaluate its role in the regulation of muscle development, appetite, the immune system, and sleep cycles. GHRP-2 remains orally and sublingually active and hence does not require an intravenous introduction for its physiological efficacy.

SPECIFICATIONS

AKA: Pralmorelin

Molecular Formula: C45H55N9O6

Molecular Weight: 817.9 g/mol

Sequence: H-D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2

PubChem: CID 6918245

CAS Number: 158861-67-7

Reconstitution: Required

GHRP-2 in Medical Research Studies

1. GHRP-2 Peptide, May Protect the Heart
Studies in fetal heart cell culture lines have shown that GHRP-2 and its analogs (GHRP-1 and GHRP-6) can help to protect cardiac cells by minimizing apoptosis or programmed cell death. The peptides thus help to protect cardiac muscles from reduced supply of blood and nutrients, which ensues a cardiac arrest. The use of Hexarelin, a GHRP-2 analog, has shown that these peptides associate with a specific receptor. Identification of new tissue-specific receptors thus may lead to the discovery of novel pathways for newer drugs, as well as improve our knowledge of the human physiology and mechanisms to avoid dysfunction.

2. Protect and Enhance Muscle Structure
Research in yaks shows that GHRP-2 can stimulate the growth of muscles in two ways: enhanced protein synthesis and accumulation, as well as reduced protein degradation. The study demonstrated that GHRP-2 helps to overcome natural growth limitation that occurs in yaks because of food deprivation, adverse environmental conditions (such as cold), and disease. The most significant observation has been the role of Pralmorelin in reducing muscle atrophy through repression of atrogin-1 and MuRF1- proteins, which regulate muscle degradation pathways. Therefore, GHRP-2 may be employed for conditions associated with decreased catabolism, commonly observed in chronic illnesses such as autoimmune diseases and cancer, among others.
The peptide helps to stimulate muscle protein deposition through the activation of growth hormone and insulin-like growth factor-1. The combinatorial effect of enhanced synthesis and decreased protein degradation helps increase lean body mass even under unfavorable physiological conditions.

3. Stimulates Appetite
Pralmorelin improves appetite and thereby the intake of food. This holds relevance in the backdrop of chronic diseases where appetite stimulation is an important part of overall health care. The ability of the peptide to easily and reliably stimulate the appetite could be beneficial for chronically ill patients and help to improve long-term outcomes.

4. Improves the Immune System
GHRP-2 has been shown to enhance the functions of the thymus, an organ that helps protect and mature certain cells of the immune system, especially the T lymphocytes. T lymphocytes are crucial for adaptive immunity and our physiological capacity to combat complex infections. However, the efficacy of the thymus diminishes with age, which causes many age-related problems ranging from insufficient tissue repair to poor immunity. This often leads to an inability to ward off infections, guard against cancer, and perform normal tissue functions. In such cases, GHRP-2 has demonstrated the capacity to rejuvenate the thymus, thereby promoting the number and diversity of T-cells, thus boosting the body’s general immunity.

5. May Affect Pain Perception
It was initially thought that GHRP-2 decreases pain associated with osteoarthritis in animal models through the stimulation of growth hormone production and the repair of damaged tissues. However, it has been observed that GHRP-2 causes pain relief before tissue repair and this happens due to its action on opioid receptors.
There are four known opioid receptors. Most opioid pain medications, unfortunately, mediate a universal action on all four receptors. The medicines’ generic mode of action can create challenges as the receptors have differential and diverse functions. Some of the receptors influence pain; some affect sensations such as wakefulness and breathing, while still others impact addiction. GHRP-2, on the other hand, is a selective opioid receptor agonist, binding uniquely to the receptors responsible for pain relief, addiction, and sedation. This observation indicates that selective opioid agonists can help to avoid unwanted effects like respiratory distress and addiction.

6. Improves Sleep Quality
GHRP-2 has been observed to influence the sleep cycle in several ways. The peptide increases the duration of stages 3 and 4 of the sleep cycles by about 50% as well as improves the duration of REM sleep by approximately 20%. It further diminishes deviation in sleeping patterns from “normal sleep” significantly. Overall, the improvement in sleep leads to betterment in cognitive function, blood pressure, healing, and energy levels. These findings are relevant for adults but specifically for the elderly population, where sleep quality gets affected due to age. GHRP-2 can thus be useful in the improvement of sleep quality and help attain all the benefits of a complete night’s sleep in a shorter duration.
Studies have shown the peptide to have minimal to moderate side effects, low oral bioavailability, and excellent subcutaneous bioavailability in murine models. Per kg dosage in mice does not scale up to the requirement for human use.

All orders ship same day if placed by 2pm PST.  Synthesized and lyophilized in the USA.
This product is strictly for research/laboratory use only.  Human or animal use and/or consumption is strictly prohibited by law.  Only qualified and licensed professionals should handle these products.  Any information found on Biotech Peptides is strictly for educational purposes only.  Refer to our terms and conditions for more details.

Additional information

Brand

Biotech Peptides

26 reviews for GHRP-2 (10mg)

  1. Isabella Gelbero

    I am overall pleased with the whole process

  2. Jasper Hall

    The packaging: well packed, clean and sealed. If these three things are off I’d recommend finding another vendor. Given the fragile nature of peptides, I was highly impressed with the level of professionalism when I received my order.

  3. Brian McCready

    I ordered yesterday, and the items were here this morning. The turnaround time is excellent

  4. Joe Moors

    My order got stuck in customs. Took a few weeks to get cleared but I finally received it. Could’ve been smoother but I understand thats out of your control.

  5. Sarah Diaz

    Very professional, they took their time with me and answered any questions I had. They assured me the products will not be damaged and get to me within the next 24 hours. They did. I had worries with the temperature and making sure no product was spoiled or ruined but they all looked good to me.

  6. Cody Raybourn

    Smooth sailing with them, keep it up

  7. Matthew Brugner

    Great turnaround time, good prices, would like to see how they keep up with supplies

  8. Aspen Sanders

    I was really scared to get into peptides at first, but Danni from CS took me under their wing and put all of my fears at ease. Now every time I need any info, I call and they solve it right away

  9. Sherwin Rodriguez

    I find the blog part of the website to be informative and interesting. They’re always short, to the point, and current.

  10. Isreal Revivo

    Amazing product

  11. Erick Smith

    I’ve seen amazing results with this product and I can whoheartedly say it is worth every penny

  12. Erick Smith

    I’ve seen amazing results with this product and I can whoheartedly say it is worth every penny

  13. Jeanne Gee Tran

    Always a pleasure doing business with Biotech

  14. Jon Jiang

    My favorite supplier, always quick to help and never fail at providing quality.

  15. Demitri Yermakov

    Been shopping with them a few months. Everything always checks out. Have had an instance or two where shipping was late but again not something they can control.

  16. Arthur Gibbs

    LOVE THEIR PEPTIDE QUALITY, HAVE NOT COME ACCROSS ONES LIKE THEIRS. MY SUGGESTION WOULD BE TO CREATE GROUP BUNDLES AND DEALS FOR PRODUCTS BOUGHT TOGTHER.

  17. Simon Irving

    Everything is so simple with them. I have seen a bunch of people on other sites struggling to get a response or solve a problem, only receiving an automated message back. With Biotech everything is so easy and drama-free. Totally recommend

  18. Edward Owen

    In my opinion they’re one of the top 3 peptide companies.

  19. ronald jones

    I have been working with this company since they first started and really happy that they have maintained the best customer service and top of the line products.

  20. Caleb Wood

    Have ordered with them multiple times in the last few months. I can report that I have not had any complaints or concerns. Packaging is fine, no breaks or damaged peptides. Bac waters and promotional codes are frequently sent out as well.

  21. john samir

    I like the Bac water they send! Works well!

  22. David Nguyen

    Peptides are great. Research is really taking off and showing results I have not seen before with other company peptides.

  23. Bruce Whitney

    They work well and are the purest I have worked with thus far.

  24. Jesse Saywell

    Not only is their products the best I have ever come across but the way they train their employees is out of this world. Always receive the best service and no long wait for calls or emails. They have well trained staff that that are quick on their feet to solve issues too.

  25. Leo Hoffman

    Blogs are up to date with some valuable information about peptides! I like that it also has a link to the specific peptide as well; Makes it easier to find and purchase.

  26. Brady Basso

    Biotech is in my top 5 suppliers. I Like using a variety of peptide suppliers and they are one of the few I gear towards buying from.

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