[email protected]
MY ACCOUNT         |         Cart
GHRP-6 (5mg)
Certificate of Analysis - GHRP-6 5MG
HPLC - GHRP-6 5MG
Mass Spectrometry - GHRP-6 5MG

GHRP-6 (5mg)

(22 customer reviews)

$21.00

GHRP-6 peptides are Synthesized and Lyophilized in the USA.

Discount per Quantity

Quantity 5 - 910 +
Discount 5%10%
Price $19.95$18.90
Orders over $200 receive:
FREE - 30ml bottle of bacteriostatic water
(Required for reconstitution)
FREE - USPS priority shipping
Add to wishlist
SKU: GHRP-6-5mg Category:

Description

What is the GHRP-6 peptide?

GHRP-6 peptide is studied for its potential as a powerful stimulant that helps release natural growth hormone (GH) from the anterior pituitary gland. In addition, it may also act as a ghrelin/growth hormone receptor agonist and is amongst the ghrelin analogs developed in recent decades. It has been observed to deliver a positive influence on cardiac muscle cells, scar formation, memory formation, sex motivation, and the neurons associated with Parkinson’s disease. The peptide is orally and sublingually active and moderately to highly specific in its action.

GHRP-6 Specifications

Molecular Formula: C46H56N12O6

Molecular Weight: 873.032 g/mol

Sequence: His-D-Trp-Ala-Trp-D-Phe-Lys

PubChem: CID 9919153

CAS Number: 87616-84-0

Reconstitution: Required

GHRP-6 Research

GHRP-6 Peptide and Parkinson’s
A study conducted in 2018 highlighted the prevalence of ghrelin receptors in substantia nigra, a part of the brain known to get affected in Parkinson’s disease.[1] Further, the scientists suggested that they “found a dramatic decrease in the expression of GHSR in PD-specific induced pluripotent stem cell (iPSC)-derived dopaminergic (DAnergic) neurons generated from patients carrying parkin gene (PARK2) mutations”. Patients genetically predisposed to the disease also showed a significant reduction in ghrelin receptors in their substantia nigra. It was observed that genetically modulated rats also exhibit Parkinson’s symptoms when an antagonist is administered. Therefore, agonists like GHRP-6 may be potentially beneficial in the treatment of Parkinson’s disease. Scientists hypothesize that the peptide associated with receptors present in the substantia nigra decreases neuronal apoptosis and thus may subside or ameliorate the onset of this disease.

GHRP-6 and Brain Tissue Protection
The role of the GHRP-6 peptide in the amelioration of stroke has been studied using appropriate animal models. The timely administration of the peptide appears to protect the brain tissue from reduced blood supply (following a stroke) and may help in recovery from memory lapses due to stroke.[2] At a molecular level, the peptide and its analogs may prevent apoptosis of neurons of the central nervous system which would prevent genetic reprogramming and inflammation.

GHRP-6 and Memory
Scientists have been investigating the role of physical activity in learning and memory formation. It has been observed that physical activity such as exercise helps to enhance cognitive learning, particularly when it is done immediately following a learning activity. However, the precise mechanism remains unknown. Initially, exercise was thought to help cognition through improved blood circulation in the brain and increased growth hormone production. Studies on rodent models have highlighted how GHRP-6 may help to consolidate newly created memories and transform short-term memories into long-term storage.[3] Significant scientific observations further posit the beneficial role of ghrelin/GHRP-6 in spatial learning tasks. Growth hormone secretagogues such as ghrelin may bring about exercise-induced cognitive improvements. Hence, the role of GH may be possibly indirect and perhaps secondary to these peptides.

GHRP-6 and Cardiac Issues
The GHRP-6 peptide was observed to inhibit free radical-mediated cytotoxicity of cardiac cells in porcine models.[4] The researchers commented that “Levels of oxidative stress markers suggested that GHRP6 prevented myocardial injury via a decrease in reactive oxygen species and by the preservation of antioxidant defence systems.” It may be used to develop medicines to protect the viable cardiac tissues from damage after cardiac arrest. Such a medication would be helpful not only in reducing the chances of death but also in overcoming any long-term adverse effects caused by cardiac arrest.

GHRP-6 and Sex Motivation, Mood
Studies on male rats have observed the role of ghrelin receptors in the central nervous system in modulating sexual behavior and motivation. Increased amounts of ghrelin have appeared to stimulate sexual impulses. GHRP-6 and its modified counterpart (which may antagonize the ghrelin receptor) have suggested that ghrelin receptors in specific brain areas may influence sexual and reward-seeking conduct.[5] There is also data to suggest that ghrelin may influence mood as part of its impact on motivation. The peptide and its analogs appear to help improve brain function associated with lifting moods, stress relief, and overcoming depression in murine models.[6] GHRP-6 may therefore have the potential to treat stress, depression, anxiety, and related mood disorders.

GHRP-6 and Scarring, Skin Improvement
GHRP-6 researchers hypothesize the peptide may have the potential to aid in the survival of diverse kinds of cells by decreasing programmed cell death. The peptide is also associated with the CD36 receptor and may help to promote blood vessel growth, particularly in wounds. Experiments with GHRP-6 and rat models also suggest it may be effective in faster wound closure in rats. It appears to help in rapid wound healing and the formation of extracellular matrix proteins such as collagen, promoting the overall correct organization of tissue around a scar and thus reducing the appearance of scar marks. Hypertrophic scars, like keloids, occur due to improper deposition of matrix proteins.[7] Scientists suggest that GHRP-6 may block this aberrant wound healing process, and would be potentially useful for people who delay surgery to avoid such painful after-effects and aesthetic changes. Studies in GHRP-6 have reported minimal to moderate side effects, low oral bioavailability, and excellent subcutaneous bioavailability in murine models of study. The dosage (per kg) required in mice does not match up to that required for humans.[8]

References

  1. Suda, Y., Kuzumaki, N., Sone, T., Narita, M., Tanaka, K., Hamada, Y., Iwasawa, C., Shibasaki, M., Maekawa, A., Matsuo, M., Akamatsu, W., Hattori, N., Okano, H., & Narita, M. (2018). Down-regulation of ghrelin receptors on dopaminergic neurons in the substantia nigra contributes to Parkinson’s disease-like motor dysfunction. Molecular brain, 11(1), 6. https://doi.org/10.1186/s13041-018-0349-8
  2. Subirós, N., Pérez-Saad, H. M., Berlanga, J. A., Aldana, L., García-Illera, G., Gibson, C. L., & García-Del-Barco, D. (2016). Assessment of dose-effect and therapeutic time window in preclinical studies of rhEGF and GHRP-6 coadministration for stroke therapy. Neurological research, 38(3), 187–195. https://doi.org/10.1179/1743132815Y.0000000089
  3. Huang, C. C., Chou, D., Yeh, C. M., & Hsu, K. S. (2016). Acute food deprivation enhances fear extinction but inhibits long-term depression in the lateral amygdala via ghrelin signaling. Neuropharmacology, 101, 36–45. https://doi.org/10.1016/j.neuropharm.2015.09.018
  4. Berlanga, J., Cibrian, D., Guevara, L., Dominguez, H., Alba, J. S., Seralena, A., Guillén, G., López-Mola, E., López-Saura, P., Rodriguez, A., Perez, B., Garcia, D., & Vispo, N. S. (2007). Growth-hormone-releasing peptide 6 (GHRP6) prevents oxidant cytotoxicity and reduces myocardial necrosis in a model of acute myocardial infarction. Clinical science (London, England : 1979), 112(4), 241–250. https://doi.org/10.1042/CS20060103
  5. Hyland, L., Rosenbaum, S., Edwards, A., Palacios, D., Graham, M. D., Pfaus, J. G., Woodside, B., & Abizaid, A. (2018). Central ghrelin receptor stimulation modulates sex motivation in male rats in a site dependent manner. Hormones and behavior, 97, 56–66. https://doi.org/10.1016/j.yhbeh.2017.10.012
  6. Huang, H. J., Chen, X. R., Han, Q. Q., Wang, J., Pilot, A., Yu, R., Liu, Q., Li, B., Wu, G. C., Wang, Y. Q., & Yu, J. (2019). The protective effects of Ghrelin/GHSR on hippocampal neurogenesis in CUMS mice. Neuropharmacology, 155, 31–43. https://doi.org/10.1016/j.neuropharm.2019.05.013
  7. Mendoza Marí, Y., Fernández Mayola, M., Aguilera Barreto, A., García Ojalvo, A., Bermúdez Alvarez, Y., Mir Benítez, A. J., & Berlanga Acosta, J. (2016). Growth Hormone-Releasing Peptide 6 Enhances the Healing Process and Improves the Esthetic Outcome of the Wounds. Plastic surgery international, 2016, 4361702. https://doi.org/10.1155/2016/4361702
  8. Fernández-Mayola, M., Betancourt, L., Molina-Kautzman, A., Palomares, S., Mendoza-Marí, Y., Ugarte-Moreno, D., Aguilera-Barreto, A., Bermúdez-Álvarez, Y., Besada, V., González, L. J., García-Ojalvo, A., Mir-Benítez, A. J., Urquiza-Rodríguez, A., & Berlanga-Acosta, J. (2018). Growth hormone-releasing peptide 6 prevents cutaneous hypertrophic scarring: early mechanistic data from a proteome study. International wound journal, 15(4), 538–546. https://doi.org/10.1111/iwj.12895
All orders ship same day if placed by 12 PST.
This product is strictly for research/laboratory use only.  Human or animal use and/or consumption is strictly prohibited by law.  Only qualified and licensed professionals should handle these products.  Any information found on Biotech Peptides is strictly for educational purposes only.  Refer to our terms and conditions for more details.

Additional information

Brand

Biotech Peptides

22 reviews for GHRP-6 (5mg)

  1. Samantha Singh –

    Will surely buy again

  2. Finn Campbell –

    Your products, prices and overall service is exceptional

  3. Brian S. Brian S. Casselberry –

    Their peptides last a while. Still have it since December. Because the order was made in the midst of the holiday season, there was some delay but I expected that.

  4. Jason Van Camp –

    A wide variety of peptides may be delivered quickly. Over the last year, I’ve had no problems with them and have used them regularly.

  5. Virginia O. –

    The bank transfer proceeded without a hitch, and I got my peptides in a timely manner. In addition, customer care was quick to respond.

  6. Jenna Cooley –

    Been buying their products for 2 months now. Since they’re based in southern Cali we always get products in super fast!

  7. Sarah Watkins –

    I once got an order that had its box torn in one of the corners. It was just a small tear and everything was inside. I assume the tear was the shipping company’s fault, but the company still sent me some freebies for the trouble.

  8. Ben Smith –

    I feel like they are a bit pricey, but honestly, I also think when it comes to peptides it’s better to splurge on quality

  9. Joud Ahmed –

    Biotech has proven to me time and time again that their peptides are of the highest quality and that their care of the products is unlike any other company.

  10. Kim Jasper –

    Hapy with this product. Definitely need to order other peptides from here 🙂

  11. Mark Miller –

    Started with them when they first came about, Quality and service has remained the same.

  12. Alex Pons –

    Bought from them 5 times in the last 4 months. Everything is always up to par. No damages to the vials, no issues with qulaity.

  13. Vincint Herrera –

    Products always performed to the highest level of quality

  14. Phil S –

    Recieved everything in a timly matter and with no visible damages on the vials. Vials also were not spoiled.

  15. Zane S. –

    It’s always a pleasure doing business with you guys

  16. Jane Winters –

    Exactly what I was looking for. Other places seemed to have it out of stock, they did not!

  17. A. Merced –

    The company is always consistent with their products. I do wish they had some bundle package as I keep buying a few together that have excess products.

  18. AJ Chang –

    Jamie was the customer service rep I had the pleasure of working with. I recently started at a lab where peptides are high in need and decided to check out if Biotech could offer me any type of deals or discount code I could use with every purchase. Jamie assured me it’s no problem and they do this with customers with needs such as mine. So far so good, the code they gave me checks out and prices are actually not as bad as others I have seen within the past week.

  19. W. Arias –

    Fair prices for good quality research peptides. 10/10

  20. Gorden Greer –

    Love that its USA made!

  21. Bryce Blythers –

    10/10

  22. Jake Dinh –

    Blogs are informative and help keep me up to date with new information

Add a review

Related products