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GHRP-6 (5mg)
GHRP-6 (5mg) COA
GHRP-6 (5mg) LC
GHRP-6 (5mg) MS

GHRP-6 (5mg)

(22 customer reviews)

$21.00

GHRP-6 peptides are Synthesized and Lyophilized in the USA.

Discount per Quantity

Quantity 5 - 910 +
Discount 5%10%
Price $19.95$18.90
Orders over $200 receive:
FREE - 30ml bottle of bacteriostatic water
(Required for reconstitution)
FREE - USPS priority shipping
SKU: GHRP-6-5mg Category:

Description

GHRP-6 Peptide

GHRP-6 PEPTIDE is studied for its potential as a growth hormone-releasing hormone agonist, speculated to facilitate growth hormone release from the anterior pituitary gland. In addition, it may also act as a ghrelin/growth hormone receptor agonist and is amongst the ghrelin analogs developed in recent decades. It has been suggested to deliver a positive influence on cardiac muscle cells, fibrosis, and possible neurological impacts.

Specifications

Molecular Formula: C46H56N12O6

Molecular Weight: 873.032 g/mol

Sequence: His-D-Trp-Ala-Trp-D-Phe-Lys

GHRP-6 Peptide Research

GHRP-6 PEPTIDE AND Neurological dysfunction
A study conducted in 2018 highlighted the prevalence of ghrelin receptors in substantia nigra, a part of the brain considered to be impacted in the pathology Parkinson’s Disease.[1] Further, the scientists noted that they “found a dramatic decrease in the expression of GHSR in PD-specific induced pluripotent stem cell (iPSC)-derived dopaminergic (DAnergic) neurons generated from [research models] carrying parkin gene (PARK2) mutations”. Genetically predisposed cases are posited to exhibit a significant reduction in ghrelin receptors in their substantia nigra. It was observed that genetically modulated rats may exhibit Parkinson’s symptoms when an antagonist is present. Scientists hypothesize that the peptide associated with receptors present in the substantia nigra may potentially decrease neuronal apoptosis and thus may subside or ameliorate the onset of this disease.

GHRP-6 PEPTIDE AND BRAIN TISSUE
The role of the GHRP-6 peptide in ameliorating stroke has been evaluated in animal model research. Exposure to GHRP-6 may potentially mitigate the reduction of blood supply to brain tissues following a stroke, and may participate in memory recall functions which may be imperiled during a stroke.[2] At a molecular level, the peptide and its analogs may prevent apoptosis of neurons of the central nervous system, preventing genetic reprogramming and inflammation.

GHRP-6 AND Cognitive Function
Scientists have been investigating the role of physical activity in cognitive functions encompassing learning and memory formation. It has been hypothesized that physical activity may support such functions. However, the precise mechanism has remained elusive. Initially, researchers suggested that physical activity facilitated improved blood circulation in the brain and thereby may have increased growth hormone production. Studies on rodent models have posited that GHRP-6 may support the transfer of short-term memories into long-term storage.[3] Significant scientific observations further posit the active role of ghrelin/GHRP-6 in spatial learning tasks.

GHRP-6 AND CARDIAC TISSUES
The GHRP-6 peptide was suggested to potentially inhibit free radical-mediated cytotoxicity of cardiac cells in porcine models.[4] The researchers commented that “Levels of oxidative stress markers suggested that GHRP6 prevented myocardial injury via a decrease in reactive oxygen species and by the preservation of antioxidant defense systems.” Research is ongoing in this area.

GHRP-6 AND Reproductive activity
Studies on male rats have hypothesized the positive correlation of ghrelin receptors in the central nervous system in modulating arousal and mating impulses. GHRP-6 peptide and its modified counterpart (which has been suggested to antagonize the ghrelin receptor) may influence brain areas that facilitate reward-seeking conduct.[5] There is also data to suggest that ghrelin may influence mood. The peptide and its analogs appear to impact brain function associated with mood, stress hormone secretion, and reward behavior in murine models.[6]

GHRP-6 AND Fibrosis, skin cells
GHRP-6 researchers hypothesize the peptide may contribute to cell survival by decreasing programmed cell death (apoptosis). The peptide has been associated with the CD36 receptor and researchers suggest that it may stimulate blood vessel growth, particularly in areas of damaged tissue. Experiments with GHRP-6 peptide and rat models suggest it may hasten natural repair processes. It appears to support the formation of extracellular matrix proteins such as collagen, and the overall correct organization of tissue around a scar, thus reducing fibrosis. Hypertrophic scars, like keloids, may occur due to improper deposition of matrix proteins.[7] Scientists suggest that GHRP-6 may block this aberrant process.[8]

Disclaimer: The products mentioned are not intended for human or animal consumption. Research chemicals are intended solely for laboratory experimentation and/or in-vitro testing. Bodily introduction of any sort is strictly prohibited by law. All purchases are limited to licensed researchers and/or qualified professionals. All information shared in this article is for educational purposes only.

 

References

  1. Suda, Y., Kuzumaki, N., Sone, T., Narita, M., Tanaka, K., Hamada, Y., Iwasawa, C., Shibasaki, M., Maekawa, A., Matsuo, M., Akamatsu, W., Hattori, N., Okano, H., & Narita, M. (2018). Down-regulation of ghrelin receptors on dopaminergic neurons in the substantia nigra contributes to Parkinson’s disease-like motor dysfunction. Molecular brain, 11(1), 6. https://doi.org/10.1186/s13041-018-0349-8
  2. Subirós, N., Pérez-Saad, H. M., Berlanga, J. A., Aldana, L., García-Illera, G., Gibson, C. L., & García-Del-Barco, D. (2016). Assessment of dose-effect and therapeutic time window in preclinical studies of rhEGF and GHRP-6 coadministration for stroke therapy. Neurological research, 38(3), 187–195. https://doi.org/10.1179/1743132815Y.0000000089
  3. Huang, C. C., Chou, D., Yeh, C. M., & Hsu, K. S. (2016). Acute food deprivation enhances fear extinction but inhibits long-term depression in the lateral amygdala via ghrelin signaling. Neuropharmacology, 101, 36–45. https://doi.org/10.1016/j.neuropharm.2015.09.018
  4. Berlanga, J., Cibrian, D., Guevara, L., Dominguez, H., Alba, J. S., Seralena, A., Guillén, G., López-Mola, E., López-Saura, P., Rodriguez, A., Perez, B., Garcia, D., & Vispo, N. S. (2007). Growth-hormone-releasing peptide 6 (GHRP6) prevents oxidant cytotoxicity and reduces myocardial necrosis in a model of acute myocardial infarction. Clinical science (London, England : 1979), 112(4), 241–250. https://doi.org/10.1042/CS20060103
  5. Hyland, L., Rosenbaum, S., Edwards, A., Palacios, D., Graham, M. D., Pfaus, J. G., Woodside, B., & Abizaid, A. (2018). Central ghrelin receptor stimulation modulates sex motivation in male rats in a site dependent manner. Hormones and behavior, 97, 56–66. https://doi.org/10.1016/j.yhbeh.2017.10.012
  6. Huang, H. J., Chen, X. R., Han, Q. Q., Wang, J., Pilot, A., Yu, R., Liu, Q., Li, B., Wu, G. C., Wang, Y. Q., & Yu, J. (2019). The protective effects of Ghrelin/GHSR on hippocampal neurogenesis in CUMS mice. Neuropharmacology, 155, 31–43. https://doi.org/10.1016/j.neuropharm.2019.05.013
  7. Mendoza Marí, Y., Fernández Mayola, M., Aguilera Barreto, A., García Ojalvo, A., Bermúdez Alvarez, Y., Mir Benítez, A. J., & Berlanga Acosta, J. (2016). Growth Hormone-Releasing Peptide 6 Enhances the Healing Process and Improves the Esthetic Outcome of the Wounds. Plastic surgery international, 2016, 4361702. https://doi.org/10.1155/2016/4361702
  8. Fernández-Mayola, M., Betancourt, L., Molina-Kautzman, A., Palomares, S., Mendoza-Marí, Y., Ugarte-Moreno, D., Aguilera-Barreto, A., Bermúdez-Álvarez, Y., Besada, V., González, L. J., García-Ojalvo, A., Mir-Benítez, A. J., Urquiza-Rodríguez, A., & Berlanga-Acosta, J. (2018). Growth hormone-releasing peptide 6 prevents cutaneous hypertrophic scarring: early mechanistic data from a proteome study. International wound journal, 15(4), 538–546. https://doi.org/10.1111/iwj.12895
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This product is strictly for research/laboratory use only.  Human or animal use and/or consumption is strictly prohibited by law.  Only qualified and licensed professionals should handle these products.  Any information found on Biotech Peptides is strictly for educational purposes only.  Refer to our terms and conditions for more details.

Additional information

Brand

Biotech Peptides

22 reviews for GHRP-6 (5mg)

  1. Samantha Singh –

    Will surely buy again

  2. Finn Campbell –

    Your products, prices and overall service is exceptional

  3. Brian S. Brian S. Casselberry –

    Their peptides last a while. Still have it since December. Because the order was made in the midst of the holiday season, there was some delay but I expected that.

  4. Jason Van Camp –

    A wide variety of peptides may be delivered quickly. Over the last year, I’ve had no problems with them and have used them regularly.

  5. Virginia O. –

    The bank transfer proceeded without a hitch, and I got my peptides in a timely manner. In addition, customer care was quick to respond.

  6. Jenna Cooley –

    Been buying their products for 2 months now. Since they’re based in southern Cali we always get products in super fast!

  7. Sarah Watkins –

    I once got an order that had its box torn in one of the corners. It was just a small tear and everything was inside. I assume the tear was the shipping company’s fault, but the company still sent me some freebies for the trouble.

  8. Ben Smith –

    I feel like they are a bit pricey, but honestly, I also think when it comes to peptides it’s better to splurge on quality

  9. Joud Ahmed –

    Biotech has proven to me time and time again that their peptides are of the highest quality and that their care of the products is unlike any other company.

  10. Kim Jasper –

    Hapy with this product. Definitely need to order other peptides from here 🙂

  11. Mark Miller –

    Started with them when they first came about, Quality and service has remained the same.

  12. Alex Pons –

    Bought from them 5 times in the last 4 months. Everything is always up to par. No damages to the vials, no issues with qulaity.

  13. Vincint Herrera –

    Products always performed to the highest level of quality

  14. Phil S –

    Recieved everything in a timly matter and with no visible damages on the vials. Vials also were not spoiled.

  15. Zane S. –

    It’s always a pleasure doing business with you guys

  16. Jane Winters –

    Exactly what I was looking for. Other places seemed to have it out of stock, they did not!

  17. A. Merced –

    The company is always consistent with their products. I do wish they had some bundle package as I keep buying a few together that have excess products.

  18. AJ Chang –

    Jamie was the customer service rep I had the pleasure of working with. I recently started at a lab where peptides are high in need and decided to check out if Biotech could offer me any type of deals or discount code I could use with every purchase. Jamie assured me it’s no problem and they do this with customers with needs such as mine. So far so good, the code they gave me checks out and prices are actually not as bad as others I have seen within the past week.

  19. W. Arias –

    Fair prices for good quality research peptides. 10/10

  20. Gorden Greer –

    Love that its USA made!

  21. Bryce Blythers –

    10/10

  22. Jake Dinh –

    Blogs are informative and help keep me up to date with new information

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