Oxytocin, which is also known as the Love Hormone, is a constitutionally developing peptide hormone and neuropeptide made in the hypothalamus and liberated by the posterior pituitary gland. Biologically, it is liberated during the birth of a child and helps in stimulating the uterine contractions during labor assisting in delivering a baby. After the baby is born, this hormone plays a significant role in social bonding between the mother and the child and also stimulates lactation in the mother. This “bonding activity” is the one due to which the “Love Hormone Connotation” has risen.

Oxytocin is comparatively a small 9 residue peptide that consists of a single disulphide bond and it is the 1st synthetic peptide to be developed for human utilisation. In 1906, Dale was the one to originally isolate this peptide. In the early 1950s, Victor du Vigneaud did the successful sequencing and then afterwards synthesized it. In 1955, for the work conducted on Oxytocin, Victor du Vigneaud was also awarded the Nobel Prize. Oxytocin is a peptide that is sustained and is found overall in the vertebrate species.

During Childbirth, Syntocinon or Pitocon, the Synthetic Oxytocin, is prescribed regularly to induce and augment labour. Rapid heartbeat and unusual bleeding are sometimes observed as the side effects. In 1998 it was evaluated by the Journal of the American Medical Association that in the US, 16% of the labors are induced and an additional 16% of labors that initiate instinctively are supplemented with the inducing drugs. Just post-birth, Oxytocin is also applied to avert postpartum hemorrhage if the contraction of the uterus is not continued and the bleeding is not stopped. Oxytocin can rupture the uterus if it is delivered in too much quantity and top rapidly.

The Nasal Spray formulation of Oxytocin is sometimes, although rarely, provided to the mothers having difficulty with milk let-down in the initial few days of nursing.

Because of the impersonating roles of Oxytocin in childbirth and nursing, researchers have observed Oxytocin for many years, primarily as a pregnancy hormone. In addition to this, it can also be used to induce termination or complete a miscarriage.

In many recent studies, scientists have revealed numerous effects of Oxytocin in both men and women. Oxytocin has shown much more pleiotropic effects than the realisation of the scientists. A wider role of Oxytocin was suspected by the scientists when they observed that the receptor reaching high concentrations in the laboring uterus is also found in other tissues like the reproductive tract, heart, and brain, in both women and men. In addition to this, many researchers also suspect that there are one or more than one Oxytocin receptors that are still unidentified. In the brain, Oxytocin is shown to play a large and unexplored role. In addition to being a hormone that is circulated in the bloodstream, it is also a neurotransmitter that travels in the brain’s nerve cells and at another place also. Cells of the hypothalamus make oxytocin and transfer it to the pituitary gland and also to the different regions of the brain. Moreover, oxytocin is not only produced by the cells of the hypothalamus but the heart, testicles, ovaries, and blood vessel walls have also shown to make their own oxytocin. Some research studies have also shown that oxytocin might help benefit people with Anxiety, Autistic Spectrum Disorder (ASD), and Irritable Bowel Syndrome (IBS).

Oxytocin is The Love Hormone?

Oxytocin is not only associated with childbirth and lactating mothers but the researchers in 2012 have also shown that people who are in the initial stages of romantic attachment have higher levels of oxytocin than those who are non attached and single and the levels have been shown to persist for at least 6 months. The release of oxytocin is stimulated during sexual activities. Some studies have shown that in women the reason behind this might be the increased uterine motility to help sperm reach their destination.

In addition to the effects of oxytocin in the uterus and lactation, it has also been shown to impact social, cognitive, and emotional behaviours when released in certain parts of the brain. Some research studies have shown the impacts of oxytocin on pro-social behaviours and emotional responses that contribute to trust, relaxation, and psychological stability. In the research studies in several species, it has been observed that brain oxytocin reduces stress responses, including anxiety.

Disclaimer: The products mentioned are not for human or animal consumption. All the information shared in this article is for educational purposes only.

Semax enhance memory and protect the brain?

Semax Stimulates Neurogenesis. Scientists observed Semax at dosage of 50 ug/kg body weight of rats to upregulate BDNF protein by 1.4 fold along with 1.6 fold increase of trkB tyrosine phosphorylation. There is also a simultaneous improvement of exon III BDNF and trkB...

Ipamorelin Cost: What to Know in 2021

What Is Ipamorelin? Originally developed by Novo Nordisk, Ipamorelin is a synthetic and a very selective agonist of the GHS receptor used for treating postoperative ileus. Ipamorelin was a derivative of the growth hormone-releasing peptide-1, which is itself derived...

Ipamorelin vs GHRP-2

Ipamorelin and GHRP-2 are synthetic peptides which both enhance the secretion of growth hormone. Owing to the identical physiological role, they are often mistaken to be one and same. On the contrary, both the molecules are very distinctly different from each other...