Receptor Grade IGF-1 LR3 (100mcg)

(20 customer reviews)

$27.00

Discount per Quantity

QuantityDiscountPrice
5 - 95%$25.65
10 +10%$24.30
Orders over $200 receive:
FREE - 30ml bottle of bacteriostatic water
(Required for reconstitution)
FREE - USPS priority shipping
SKU: Receptor-Grade-IGF-1-LR3-100mcg Category:

Description

IGF-1 LR3 RECEPTOR GRADE SPECIFICATIONS

Molecular Formula:C990H1528N262O300S7

Molecular Weight: 9,111 da

Sequence: MFPAMP LSSLF VNGPR TLCGA ELVDA LQFVC GDRGF YFNKP TGYGS SSRRA PQTGIV DECCFR SCDLRR LEMY CAPLK PAKSA

CAS Number: 946870-92-4

Reconstitution: Required

What is Receptor Grade IGF-1 LR3 peptide?

Receptor Grade IGF-1 LR3 peptide is a prime research reagent used in studies for cellular growth, IGF receptors, and IGF binding proteins. It is more powerful than rH IGF-1 and Media Grade IGF-1 LR3 in-vitro because of the significant improvement in its biological activity (since it exhibits a stronger affinity for the IGF receptor). This enhanced biological activity distinguishes between Receptor Grade IGF-1 LR3 and Media Grade (standard) IGF-1 LR3. Media grade IGF-1 LR3 is routinely used in commercial cell culture compared to mammalian cell culture. It is also used as a research reagent (at an economical cost) for studies where biological potency is not crucial. Receptor Grade IGF-1 LR3 should be the reagent of choice to achieve optimum results when performing any animal study, in-vitro cell-based assays, and commercial production. Growth of mammalian cells in the presence of low concentrations of Long R3 IGF-1 results in better productivity than standard concentrations of insulin and/or standard IGF-1. IGF-1 LR3 is more capable of inducing the type 1 IGF receptor, promoting an elevated level of intracellular signaling, cellular proliferation, and apoptosis inhibition.
Receptor Grade IGF-1 LR3 is therefore biologically more potent than standard IGF-1 LR3, in-vitro.
Hence, Receptor Grade IGF-1 LR3 can deliver superior results compared to standard IGF-1 LR3.

IGFB Binding and the Increased Biological Activity of IGF-1 LR3

The peptide brings about a more pronounced effect than IGF-1 by resisting the association of IGFB. The prolonged duration of action helps mediate the same biological effects while using smaller doses of the receptor. Certain IGF-1 derivatives, including the GPE derivative, comprising only the last three N-terminal amino acids of the IGF-1 protein, have demonstrated therapeutic effects in neurological damages such as stroke. However, the majority of the research aimed to unravel the effects of IGF-1 derivatives has been executed in non-human animal models or cell cultures.

Insulin-Like Growth Factor Receptor Interactions
IGF-1 interacts with at least two cell surface receptors: the IGF-1 receptor (IGF-1R) and the insulin receptor. The IGF-1R is referred to as the “physiologic” receptor due to its significantly higher affinity (approximately 100 times higher) for IGF-1 as compared to the insulin receptor. The association of IGF-1 and IGF-1R leads to changes in metabolism, prevention of cell death (apoptosis), promotion of cell growth (hypertrophy), differentiation and cell division (hyperplasia), normal development, and even malignant growth. IGF-1R has been involved in diverse types of cancer, such as prostate, breast, and lung cancer. IGF-1 also stimulates insulin receptors and activates them, thereby promoting glucose uptake from the bloodstream by cells. IGF-1 displays a three-fold influence on muscle cells. At the onset, IGF-1 promotes an increase in the number of muscle cells, also known as hyperplasia. Secondly, IGF-1 strongly influences the life span of satellite cells of the skeletal muscles. Satellite cells provide nutritional support to muscle cells, thereby helping them to operate efficiently. IGF-1 thus helps to build muscle tissue by improving the lifespan of these cells. Finally, IGF-1 promotes the differentiation of myoblasts. In other words, it encourages the commitment of stem cell progeny from non-specific pluripotent stem cells to dedicated muscle tissue. To conclude, IGF-1 improves muscle development by enhancing the rate at which generic stem cells are transformed into muscle cells.

All orders ship same day if placed by 2pm PST.  Synthesized and lyophilized in the USA.
This product is strictly for research/laboratory use only.  Human or animal use and/or consumption is strictly prohibited by law.  Only qualified and licensed professionals should handle these products.  Any information found on Biotech Peptides is strictly for educational purposes only.  Refer to our terms and conditions for more details.

Additional information

Brand

Biotech Peptides USA

20 reviews for Receptor Grade IGF-1 LR3 (100mcg)

  1. Alex Morales

    Biotech Peptides is my number one supplier. I always get my stuff on time and they are always very professional

  2. Noah Young

    Zero issues with Biotech so far

  3. Anders Tim

    As a returning customer over the past year, I find the products outstanding with great customer service, always delivered on time and the results from what I test is second to none.

  4. Charles Gill Charles Gill

    Had some issues regarding shipment. The guy working customer service was awesome and fixed it right away. Got the product on time even with the issues! Will defiantly be buying from here again.

  5. Grace Chamberlain

    From their reviews so far I see that they’re great. I just want to compliment how easy it is to buy the products and how simple the site was.

  6. Ti We

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  7. Rory Dean

    I’ve seen a lot of buzz around this company and their pure products lately and I ordered it myself. Hopefully, it lives up to the expectations

  8. Joy Kim

    They’re great, I just wish they had an easier way to let me know peptides are back in stock instead of having to check everyday.

  9. Alex Mitrushi

    Orders came in without a hitch. Easy process. Great stuff

  10. Heather Knauss

    love the service representatives, cant find better prices either

  11. Patrick O’Brian

    Been buying from them since July, so been with them almsot a year. Great stuff, they never disapoint.

  12. Hanna Byrne

    First timer with biotech. They were recommened to me by a work friend. Seem to have the best prices around AND good quality peptides so giving them a try.

  13. Oliver Walsh

    My company is very satisfied with Biotech. Good products, fast delivery and send out.

  14. James

    using them a year now, only had one vial broken out of maybe a 100 that I have recieved.

  15. Silas Allen

    I believe the products and service speak for themselves. Products are the real deal.

  16. Finley Alvarez

    great stuff!

  17. Steve Krulin

    They carry a lot of of different peptides. Good variety.

  18. Penny Turner

    All their products are of the highest purtiy. Have not had a terrible experince with them.

  19. Andy Vosseler

    Restocks don’t happen as frequently as I’d like. I have had to wait weeks once for a few peptides I needed for my research which set me back.

  20. Alec Beltran

    Taylor is great, My order got lost in the mail and they were able to overnight me my entire order again with no extra charges!

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