Receptor Grade IGF-1 LR3 (100mcg)

(3 customer reviews)


Discount per Quantity

5 - 95%$25.65
10 +10%$24.30
Orders over $150 receive:
FREE - 30ml bottle of bacteriostatic water
(Required for reconstitution)
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SKU: Receptor-Grade-IGF-1-LR3-100mcg Category:



Molecular Formula:C990H1528N262O300S7

Molecular Weight: 9,111 da


CAS Number: 946870-92-4

Reconstitution: Required

What is Receptor Grade IGF-1 LR3 peptide?

Receptor Grade IGF-1 LR3 peptide is a prime research reagent which is used in studies for cellular growth, IGF receptors and IGF binding proteins. It is more powerful than rH IGF-1 and Media Grade IGF-1 LR3 in-vitro because of the significant improvement in its biological activity (since it exhibits a stronger affinity for the IGF receptor). This enhanced biological activity is the distinguishing factor between Receptor Grade IGF-1 LR3 and Media Grade (standard) IGF-1 LR3. Media grade IGF-1 LR3 is routinely used in commercial cell culture as compared to mammalian cell culture. It is also used as a research reagent (at an economical cost) for studies where biological potency is not crucial. Receptor Grade IGF-1 LR3 should be the reagent of choice to achieve optimum results when performing any animal study, in-vitro cell-based assays as well as commercial production. Growth of mammalian cells in the presence of low concentrations of Long R3 IGF-1 results in better productivity as compared to standard concentrations of insulin and/or standard IGF-1. IGF-1 LR3 is more capable of inducing the type 1 IGF receptor and thereby promotes an elevated level of intracellular signaling, cellular proliferation, and apoptosis inhibition.
Receptor Grade IGF-1 LR3 is therefore biologically more potent than standard IGF-1 LR3, in-vitro.
Hence, Receptor Grade IGF-1 LR3 is capable of delivering superior results in comparison to standard IGF-1 LR3.

IGFB Binding and the Increased Biological Activity of IGF-1 LR3

The peptide brings about a more pronounced effect than IGF-1 by resisting the association of IGFB. The prolonged duration of action helps to mediate the same biological effects while using smaller doses of the receptor. Certain IGF-1 derivatives, including the GPE derivative, comprising of only the last three N-terminal amino acids of the IGF-1 protein, have demonstrated therapeutic effects in neurological damages such as stroke. However, the majority of the research aimed to unravel the effects of IGF-1 derivatives have been executed in non-human animal models or cell culture.

Insulin Like Growth Factor Receptor Interactions
IGF-1 interacts with at least two cell surface receptors: IGF-1 receptor (IGF-1R) and the insulin receptor. The IGF-1R is referred to as the “physiologic” receptor due to its significantly higher affinity (approximately 100 times higher) for IGF-1 as compared to the insulin receptor. Association of IGF-1 and IGF-1R leads to changes in metabolism, prevention of cell death (apoptosis), promotion of cell growth (hypertrophy), differentiation and cell division (hyperplasia), normal development, and even malignant growth. IGF-1R has been involved in diverse types of cancer such as prostate, breast, and lung cancer. IGF-1 also stimulates insulin receptors and activates them, thereby promoting the uptake of glucose from the bloodstream by cells. IGF-1 displays a three-fold influence on muscle cells. At the onset, IGF-1 promotes an increase in the number of muscle cells which is also known as hyperplasia. Secondly, IGF-1 strongly influences the life span of satellite cells of the skeletal muscles. Satellite cells provide nutritional support to muscle cells, thereby helping them to operate efficiently. IGF-1 thus helps to build muscle tissue by improving the lifespan of these cells. Finally, IGF-1 promotes the differentiation of myoblasts. In other words, it encourages the commitment of stem cell progeny from non-specific pluripotent stem cells to dedicated muscle tissue. To conclude, IGF-1 improves muscle development by enhancing the rate at which generic stem cells are transformed into muscle cells.
Buy Receptor Grade IGF-1 LR3 peptide, ONLY if you are a licensed researcher.

All orders ship same day if placed by 2pm PST.  Synthesized and lyophilized in the USA.
This product is strictly for research/laboratory use only.  Human or animal use and/or consumption is strictly prohibited by law.  Only qualified and licensed professionals should handle these products.  Any information found on Biotech Peptides is strictly for educational purposes only.  Refer to our terms and conditions for more details.

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Biotech Peptides USA

3 reviews for Receptor Grade IGF-1 LR3 (100mcg)

  1. Alex Morales

    This is the best. I always get my stuff on time and they are always very professional

  2. Noah Young

    Zero issues with Biotech so far

  3. Anders Tim

    As a returning customer of years, I find the products outstanding with great customer service, always delivered on time and the results from what I test is second to none.

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