Can You Take Too Much Melanotan?

by | Apr 20, 2022 | Research

Melanotan is a melatonin stimulating peptide. Melatonin is a naturally occurring hormone released from a part of the brain called the pineal gland.

Before answering whether you can take too much Melanotan, you need to understand what it is and how it works?
Let’s get to it.

What Is Melanotan, And How Does It Work?

Melanotan is a synthetically prepared peptide. The purpose of Melanotan was to produce a peptide chemically similar in structure to the body’s alpha-melanocyte-stimulating hormone (alpha-MSH). Alpha-MSH stimulates the body’s melanocortin receptors.

There are five types of melanocortin receptors, and each performs a specific function. MC-1 receptors help darken hair and skin. Melanotan mainly acts on MC-1 receptors. But the other melanocortin receptors are essential too. MC-3 receptors help in stimulating fat metabolism and appetite regulation. MC-4 receptors aid in regulating sexual function.

Melanotan partially binds to these receptors too. Therefore, it helps improve metabolism, fat burning, appetite regulation, and libido.

Your skin contains several layers of cells. Among these cells, one cell type is melanocytes. These cells release a pigment called melanin. Melanin is mainly produced as a response to sunlight. It acts as a means of protection against harmful sun radiation. Melanin imparts color to your skin.

Melanotan functions by acting on the MC-1 receptors. Once it attaches to the receptors, it signals the cells to increase melanin production. A higher level of melanin gives you darker skin and hair. It offers protection to your skin against sun-related damage and reduces the risk of skin cancer.

MT-1 vs. MT-2 – What’s The Difference?

There are two types of Melanotan: Melanotan 1 (MT-1) and Melanotan 2 (MT-2). The difference lies in their structure and how the body reacts to them. MT-1 is structurally identical to the protein naturally produced in the body. MT-2 has a slightly different structure.

The main differences among these peptides include:
● MT-1 is safer and has fewer side effects compared to MT-2.
● MT-2 has a longer half-life than MT-1.
● MT-1 is readily available but more expensive than MT-2
● MT-1 is FDA-approved for individuals who become sensitive to sunlight. MT-2 is not FDA-approved.
● MT-2 increases libido; MT-1 does not.

What Are The Benefits Of Melanotan?

One obvious benefit of Melanotan is its ability to impart color to the skin. Benefits of MT-2 include:
● Addiction: Melanotan helps reduce addictive behavior. It can help people rehabilitate from addictions such as alcohol or drugs.
● Metabolism: Melanotan helps reduce hunger and impulsive eating behavior. It can reduce the craving for fatty food. It can improve fat metabolism and body composition.
● Blood Sugar: Melanotan helps improve the regulation of blood sugar levels. It can help individuals with diabetes.
● Sexual Health: Melanotan can have beneficial effects on sexual health as well. It can improve libido and is helpful for men struggling with erectile dysfunction.

Benefits of MT-1 include:
● Photoprotection: MT-1 offers significant protection against that harmful radiation from the sun.
● Blood pressure: MT-1 may help reduce blood pressure and help individuals struggling with hypertension.
● Cognitive effects: Some research suggests that MT-1 has neuroprotective and cognition-improving properties. These properties can be helpful in conditions such as Alzheimer’s dementia.


You should note that most of the intended uses of Melanotan are for research purposes only. Melanotan for healthcare purposes should always be guided by a healthcare professional.
The initial dose of Melanotan should not exceed 500 mcg given as two divided doses. The maximum dose should not exceed 1 mg.

Can You Take Too Much Melanotan?

Yes, it is possible to take too much Melanotan. If the Melanotan dose exceeds 1 mg, you are more likely to experience side effects.

What Are The Side Effects Of Melanotan?

Melanotan is generally safe. The side effects are unlikely, especially when you take the recommended dose.

The potential side effects of Melanotan can include:
● Thickening of facial hair
● Flushing
● Vomiting
● Excessive darkening of the skin, especially skin moles
● Reduced appetite
● Increased libido and erection
● Lethargy
● Dizziness

Is It Possible to Overdose On Melanotan?

There is not a lot of research on the potential of Melanotan overdose. The potential features of Melanotan overdose could include:
● Body aches
● Excessive lethargy and fatigue
● Increased gastrointestinal side effects like vomiting and diarrhea
● Melanotan overdose can lead to an increase in heart rate and blood pressure
● It can also lead to priapism, a prolonged and painful erection. It is a medical emergency and requires medical attention.
● Melanotan overdose can cause muscle breakdown, a condition known as rhabdomyolysis. It can lead to kidney failure too.

Disclaimer: The products mentioned are not for human or animal consumption. All the information shared in this article is for educational purposes only.

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