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Adipotide FTPP (10mg)
$75.00
Adipotide FTPP peptides are Synthesized and Lyophilized in the USA.
Discount per Quantity
| Quantity | 5 - 9 | 10 + |
|---|---|---|
| Discount | 5% | 10% |
| Price | $71.25 | $67.50 |
Out of stock
Description
What is the Adipotide FTPP peptide?
Adipotide FTPP is a category of proapoptotic peptides intended to eliminate fat cells in the body[1]. They appear to cut off the blood supply specifically to the adipose tissues and not the vessels supplying blood to the rest of the body. Reports of studies performed in monkeys have suggested their ability to cause weight loss, which improves symptoms of insulin resistance and reduces the symptoms of type 2 diabetes.
Specifications
AKA: Adipotide
Molecular Formula: C152H252N44O42
Molecular Weight: 2611.41 g/mol
Sequence: Cys-Lys-Gly-Gly-Arg-Ala-Lys-Asp-CysโGly-Gly–(Lys-Leu-Ala-Lys-Leu-Ala-Lys)2
Reconstitution: Required
Adipotide FTPP Research
Adipotide FTPP and Cancer
Cancerous tissues are able to grow rapidly and become metastatic due to the abundant network of blood vessels. Suppose prohibitin, which has been found in several cancer types, is targeted. In that case, it may be possible to treat cancer in a more focused manner and avoid the associated side effects brought about due to damage to surrounding healthy tissues due to chemotherapy.
Adipotide and Glucose Tolerance
Glucose tolerance, a common parameter used to diagnose diabetes, is studied by performing a blood test and confirmed by testing fasting glucose levels. In another method, a specific amount of glucose is consumed by the patient and then blood sugar levels are estimated.
Metabolic syndromes such as diabetes have traditionally been controlled by diet and exercise. Both require immense patience and dedication as the outcomes can take months, if not years, to show significant improvement. Most patients with type 2 diabetes are prescribed metformin or sometimes insulin.
Research with adipotides has noted rapid weight-independent improvement in glucose tolerance in test subjects[2]. This highlights the observation that a reduction in white fat by adipotide FTPP may simultaneously reduce glucose tolerance irrespective of the patient’s weight. These outcomes help to elucidate the mechanisms responsible for diabetes in the first place and also propose the way for novel treatment options.
Although it is unclear whether adipotide FTPP peptide directly causes fat loss or simply decreases the appetite (an indirect factor) the former is more likely as changes in fat cell density and improved glucose tolerance have been observed even without associated weight loss.
Adipotide And Fat Loss
Phase I clinical trials were held in 2011 to investigate the fat-eliminating potential of adipotide. Research on rhesus monkeys showed the ability of this novel drug to induce apoptosis, specifically in the vessels supplying blood to the white adipose tissues[3]. The result being no blood cells and hence, the ensuing death of these fat cells. The eventual outcomes were rapid weight loss, decreased body mass index, and improved insulin sensitivity. Such changes were attributed in part to the ability of adipotide FTPP to bring about changes in the eating pattern of the monkeys, as the monkeys who demonstrated a positive weight loss also demonstrated a reduced appetite.
Research has suggested that adipotide is associated with prohibitin, a membrane protein receptor present in blood vessels of white fat tissues and some cancer cells. Adipotide FTPP testing may be used for identifying a fat-specific target for both therapeutic as well as diagnostic purposes if prohibitin is found to be expressed specifically in the vessels supplying blood to the adipose and cancerous tissues.
Future Adipotide FTPP Research
Anti-angiogenic molecules like adipotites target the blood vessels and are considered a potential treatment for cancer[4]. Most of the research with adipotides have been focused on their effects on fat loss and diabetes. They have been shown to target specifically the blood vessels of adipose tissues in which they induce apoptosis causing them to die. Studies report these peptides have minimal side effects in addition to low oral and good subcutaneous bioavailability in mice. However, the dosage cannot be directly extrapolated to humans.
References
- Kolonin, M. G., Saha, P. K., Chan, L., Pasqualini, R., & Arap, W. (2004). Reversal of obesity by targeted ablation of adipose tissue. Nature medicine, 10(6), 625โ632. https://doi.org/10.1038/nm1048
- Hossen, N., Kajimoto, K., Akita, H., Hyodo, M., & Harashima, H. (2013). A comparative study between nanoparticle-targeted therapeutics and bioconjugates as obesity medication. Journal of controlled release : official journal of the Controlled Release Society, 171(2), 104โ112. https://doi.org/10.1016/j.jconrel.2013.07.013
- Barnhart, K. F., Christianson, D. R., Hanley, P. W., Driessen, W. H., Bernacky, B. J., Baze, W. B., Wen, S., Tian, M., Ma, J., Kolonin, M. G., Saha, P. K., Do, K. A., Hulvat, J. F., Gelovani, J. G., Chan, L., Arap, W., & Pasqualini, R. (2011). A peptidomimetic targeting white fat causes weight loss and improved insulin resistance in obese monkeys. Science translational medicine, 3(108), 108ra112. https://doi.org/10.1126/scitranslmed.3002621
- Thuaud, F., Ribeiro, N., Nebigil, C. G., & Dรฉsaubry, L. (2013). Prohibitin ligands in cell death and survival: mode of action and therapeutic potential. Chemistry & biology, 20(3), 316โ331. https://doi.org/10.1016/j.chembiol.2013.02.006
All orders ship same day if placed by 2pm PST.
This product is strictly for research/laboratory use only.ย Human or animal use and/or consumption is strictly prohibited by law.ย Only qualified and licensed professionals should handle these products.ย Any information found on Biotech Peptides is strictly for educational purposes only.ย Refer to our terms and conditions for more details.
Dr. Usman (BSc, MBBS, MaRCP) completed his studies in medicine at the Royal College of Physicians, London. He is an avid researcher with more than 30 publications in internationally recognized peer-reviewed journals. Dr. Usman has worked as a researcher and a medical consultant for reputable pharmaceutical companies such as Johnson & Johnson and Sanofi.
Additional information
| Brand | Biotech Peptides |
|---|
32 reviews for Adipotide FTPP (10mg)
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Ava Martinez –
Solid company. Noticed they had stuff gone for a while. I had ordered some products that ended up being out of stock and they let me know they would send them out once they had them in. Got the products within 2 weeks so kind of long but eventually got them.
Melanie Cruz –
Legitimate peptide supplier!
Amelia Diaz –
As always great fast reliable service. See these guys for all your research needs.
Sam Ridley –
Definitely recommend Biotech peptides, the team is always happy to help with any issues or queries and is also reachable by phone if needed.
Chee Baisho –
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Bailey Sparks –
I purchased 30 vials of this blend but the billing descriptor had me confused so I accidentally filed a chargeback. Thankfully someone called me and we were able to get it sorted out and clear up the confusion.
Patricia Paiz –
Had one problem with the consistency of one product after it was diluted and I was offered a replacement. The replacement was sent out Friday and was in my mailbox Monday morning.
Jenny Nagasaki –
First class service and products.
Daniella Tiiu –
My order got lost in customs and they were quick to help try and find it for me. No luck with that but they were able to replace the order and have another sent out.
Susan Onuoha –
Excellent!
Mickael Dobre –
Very quick delivery. I received my Adipotide the next day. Probably due to the fact that the products ship out of San Diego where I’m from.
Liza Perkins –
The holiday specials make this a real bargain. I even got to use a past discount code on top of the peptide being on sale.
Naomi Sarian –
Finally found a supplier that accepts credit cards. I don’t understand why so many others do not accept credit cards. I cant imagine how much business they’re missing out on.
Rossina Koshy –
We don’t have good suppliers out here in Canada, so I like to order from Biotech Peptides. Never had a problem with customs and peptides always get in on time.
Shane Ramirez –
gran calidad
Jorri Navarro –
This place is the first place I have shopped from where I didn’t have an issue. I’m a first-time customer and have been seeing them pop up on my google search. I decided to give them a try. Really happy I did. Took many methods of payment as well. Had placed my order in the morning and was notified that it was shipped that same afternoon. Fast and efficient, can’t ask for more!
Carolyn Rider –
Products are pure, no packages I have gotten have been spoiled or broken which is a major plus.
Craig Osborne –
Had a few issues with payment. Both times they called me within an hour of me placing my order and we were able to correct it and got my stuff in time as well! they even threw in a discount code for me as well.
Vanessa Lopez –
Biotech does an exceptional job at taking care of their products and assuring it gets to us safely.
Kaleb Sharlls –
No complaints with Biotech! Admire their work they put in to get packages over to me safely. Everything is always packed in a way to protect the small vials/containers. Haven’t had a break ever and been shopping with them since last April.
Oliver Walsh –
I love dealing with the company. If there is ever an issue, which is rare, it is such a quick fix and the job gets done.
Damian Riley –
We enjoy working with Biotech. They satisfy all our companies needs and have proven to be reliable and carry high quality peptides which suit the needs of all our researchers. They typically have had all the peptides we have needed in stock and have notified us of there were any that were out of stock.
Charlotte Flores –
Really happy my package was delivered without a problem out of the country. Have had all sorts of issues with customs before so it was a nice change of events.
Alison Segal –
They constantly send me 10% offs for about every holiday or end of the month. Absoultly love it
Rob Delgado –
Peptides are as advertised and good quality. Prices are not bad and they are constantly sending discount codes or deals as a promotion.
JS Winters –
I guess there was an issue with my credit card. Taylor called me up and let me know what was going on and they were able to take my payment over the phone which was nice as I was no where near a computer. Was still able to get all my peptides in time as well.
Chantel Edwards –
They have anazing quality for what it is prcied at!
Nolan reed –
Super convinent that my information is kept for the next purchace I make. Checking out is always fast and they remember the peptides I last purchaced as well.
Dustin M –
Service is above average, call center always picks up and is able to assist me with my questions about the products or shipping. Was not too long of a wait to get ahold of someone either.
Vic Pugh –
I have previously shopped here before. They remain consistent with the quality of peptides.
Ethan Bouhadana –
Site is easy to use and full of useful information! Didn’t have a hard time at all navigating it. My products came in pretty quickly as well.
Marshall Anderson –
Ordering process is easy and not a big hassle. I have shopped with them before and they made it pretty simple for any user. Some info is saved which is nice to remember past orders or credit card number! But nothing to difficult from start to finish.