AHK-Cu (Topical) (200mg)

(20 customer reviews)


AHK-Cu peptides are Synthesized and Lyophilized in the USA.

Discount per Quantity

Quantity5 - 910 +
Orders over $200 receive:
FREE - 30ml bottle of bacteriostatic water
(Required for reconstitution)
FREE - USPS priority shipping
SKU: AHK-Cu-200mg Category:


What is the AHK-Cu Peptide?

AHK-Cu is a tripeptide that contains a copper atom linked with iron. It is a short peptide in which the copper atom is attached between the histidine and alanine residues of the alanine-histidine-lysine tripeptide. The copper atom is linked to three nitrogen atoms in this molecule.
It is found in the blood of most mammals. It has been suggested to be significantly valuable in growth regulation, death, and vascular endothelial cells (these are the cells that make the innermost layer of blood vessels). AHK-Cu has been studied extensively in laboratory models and animals because of its potential in hair growth, effects on skin health, collagen synthesis, and hair loss prevention. It appears to regulate various cellular processes primarily by controlling the production of two compounds: Vascular Endothelial Growth Factor (VEGF) and Transforming Growth Factor beta (TGF-B).[1] ccording to the researchers “TGF-beta1 induction of angiogenesis requires a rapid and transient apoptotic effect mediated by VEGF/VEGFR2.” AHK-Cu, by enhancing levels of the Vascular Endothelial Growth Factor, may activate fibroblasts and endothelial cells. Fibroblasts lead to the production of two complex compounds; elastin and collagen. These two molecules may therefore affect skin texture, tone, and elasticity. Endothelial cells are responsible for the growth and health of blood vessels that supply nutrition to hair follicles and skin cells. The activation of endothelial cells in association with the fibroblasts leads to reduced fine lines and wrinkles and increased  skin elasticity, and improved wound healing. Some laboratory studies done on human skin cells indicate an increase in collagen type 1 production to the extent of as much as 300%. It is quite promising for the future applications of AHK-Cu in anti-aging skin-care products.


AKA: Topical



SEQUENCE: Ala-His-Lys-Cu


AHK-Cu Research

AHK-Cu has been of great interest to researchers due to its potential to promote hair growth and slow down the effects of aging on skin and hair. AHK-Cu primarily exhibits this apparent effect on fibroblasts. These cells function in maintaining and growing the Extracellular Matrix (ECM), which surrounds cells. Fibroblasts secrete various biological substances, such as Vascular Endothelial Growth Factor (VEGF). These factors lead to the formation of new blood vessels. Because of these attributes, AHK-Cu has been studied extensively by cosmeceutical industries to bring them to use in anti-aging formulations.

AHK-Cu and Wrinkles
Copper and its peptide derivates are often used in the formulation of skin creams and sunscreens because of their potential to enhance collagen production. A decline in the skin levels of collagen is the hallmark of the aging process. The body stops producing more collagen with increasing age, and the existing collagen reduces its structural and functional integrity. Collagen affects the skin in several ways, such as providing structure and making more taut. Also, it has an affinity for water, so it hydrates the skin cells and the Extracellular Matrix when it enters the skin.[2] These properties of collagen reduce the appearance of wrinkles and fine lines of the skin. This attribute helps in improving the appearance of sagging skin. Several scientific studies have suggested the positive effects of AHK-Cu in skin conditioning and making it look younger and healthier.

AHK-Cu and Hair Growth/Loss
AHK-Cu appears to control hair loss by two mechanisms. First, it may stimulate the secretion of the Vascular Endothelial Growth Factor (VEGF), leading to the growth of blood vessels in the area surrounding the hair follicles. These blood vessels supply nutrition to hair follicles and promote hair growth. A reduction in the supply of these nutrients, on the other hand, will lead to hair loss. Studies have suggested that AHK-Cu may also lead to the formation of new hair follicles by promoting new blood vessels and improving blood supply to existing hair follicles. By stimulating the growth of blood vessels, AHK-Cu would be able to keep hair healthy, strong, and long. The second mechanism by which AHK-Cu may prevent hair loss via down-regulating Transforming Growth Factor beta. This would reduce the effect of dihydrotestosterone (DHT) on hair loss.[3] he scientists concluded that “The present study proposed that AHK-Cu promotes the growth of human hair follicles, and this stimulatory effect may occur due to stimulation of the proliferation and the preclusion of the apoptosis of DPCs.” Dihydrosterone is the hormone primarily responsible for male pattern baldness and progressive hair-thinning in both men and women as they age. Reducing the effect of dihydropteroate can prevent hair loss by protecting the hair follicles from negative stress. By increasing the blood supply to an existing follicle, AHK-Cu may increase and enhance hair thickness and size, leading to stronger hair. Studies also suggest that AHK-Cu may extend the hair growth phase. Generally, the hair growth cycle has 3 phases: Anagen, Telogen, and Catagen phases. Among these, AHK-Cu may both extend and trigger Anagen hair growth phases, lasting 3-5 years. This would prolong the lifespan of hair and reduces hair fall. It is an interesting tripeptide with profound potential in slowing down age-related degenerating changes, specifically in hair and skin. The results observed by laboratory researchers has so far been promising. It is expected that AHK-Cu may be made available as an over-the-counter anti-aging topical treatment. Researchers consider it a virtually side-effect-free product.


  1. Ferrari G, Cook BD, Terushkin V, Pintucci G, Mignatti P. Transforming growth factor-beta 1 (TGF-beta1) induces angiogenesis through vascular endothelial growth factor (VEGF)-mediated apoptosis. J Cell Physiol. 2009 May;219(2):449-58. doi: 10.1002/jcp.21706. PMID: 19180561; PMCID: PMC2749291.
  2. Patt, Leonard M., and A. Procyte. “Neova® DNA Repair Factor Nourishing Lotion Stimulates Collagen and Speeds Natural Repair Process.” skin 1 (2009): 2.
  3. Pyo HK, Yoo HG, Won CH, Lee SH, Kang YJ, Eun HC, Cho KH, Kim KH. The effect of tripeptide-copper complex on human hair growth in vitro. Arch Pharm Res. 2007 Jul;30(7):834-9. doi: 10.1007/BF02978833. PMID: 17703734.
All orders ship same day if placed by 2pm PST.
This product is strictly for research/laboratory use only.  Human or animal use and/or consumption is strictly prohibited by law.  Only qualified and licensed professionals should handle these products.  Any information found on Biotech Peptides is strictly for educational purposes only.  Refer to our terms and conditions for more details.

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Biotech Peptides

20 reviews for AHK-Cu (Topical) (200mg)

  1. Joseph Hoffman

    In my recent experience with this company, I was very surprised by the level of customer service and certainly a fine example of how things should be handled. I had a recent mix-up which turned out to be my fault and yet customer service called me personally, spent 15 min with me and corrected the issue.

  2. Ashley Tuminella

    I just wanted to say thanks to Taylor for helping me out! Was having a hard time checking out as there seemed to have been a glitch in their system. Taylor was able to take my order and payment over the phone!

  3. Ross Treadway

    Just got my orders. Wanted to say my experience so far is good. This is a new company I’m trying out so fingers crossed it stays this way.

  4. Anthony Do

    Very good products

  5. Serena J. Suh

    Wonderful company, I’ve been ordering in bulk from them every two weeks now. I appreciate the frequent buy discount! Been with them for 9 months now!

  6. Savannah Nay

    The site is easy to navigate and easy to the eye. I love how simple the packaging is. Vials arrived safely and faster than I thought! Then I realized it’s a local company which makes things so much better! Was scared the products could get damaged with long shipping but, doesn’t seem to be a problem with them!!

  7. Bryan Green

    Just ordered from them for the first time, was recommeneded to them by someone I used to work with.

  8. Kai Khamsy

    I’m impressed with the quality and purity of the peptide. Also impressed with how they’re synthesized in the US.

  9. Scott Thorton

    One of the fastest working companies I have come across. Put in an order in the morning and got an email by 2/3 that it was already shipped! WOW. Recieved the peptides within 24 hours.

  10. Jack Taylor

    Now. This product is pretty high up there price wise. I have noticed that they are the cheapest find for this specific one though. I could confidently say the quality is much better as well.

  11. Ava Lee

    I enjoy getting their promotional codes that they send out during holidays. I remember receiving one after my first purchase and it does help bring the cost down a little.

  12. Charlie Green

    No issues with customs. I am located in Canada for right now and even the shipping cost was not too bad.

  13. Joe T.

    Best quality in every way! Staff is spectacular as well.

  14. Cody Wann

    I had no issues when recieving my order. I did not have any issues with customs and recieved them when anticipated!

  15. ronald hawkins

    Customer service is always amazing. I have had times where packages were lost, showed up damaged or broken due to shipping and each time they have been super helpful in just fixing the problem and not giving extra headache about reshipment.

  16. Lenny Doyle

    I have been ordering peptides for a while now. Have had one issue with payment and Dani was the rep I spoke with. There was an issue an issue with my card and I received an email from them a few hours after I had placed my order. Dani was able to sort it all out for me so that I could still get my peptides in time.

  17. Cam Erickson

    Priced fairly for the quality.

  18. Samuel Fernandez

    Peptides speak for themselves!

  19. Yvette Marie

    They came recommended by my mentor. They swear their peptides are the purest on the market. They also raved about how they see a difference in their research results after only a few uses as well.

  20. Kenny Helton

    Overall everything was good, peptides are good and can’t complain about the customer service.

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