AKA: BPC 157
Molecular Formula: C62H98N16O22
Molecular Weight: 1419.5355 g/mol
Sequence: L-Valine,glycyl-L-alpha-glutamyl-L-prolyl-L-prolyl-Lprolylglycyl-L-lysyl-L-prolyl-L-alanyl-L-alpha-aspartyl-L-alpha-aspartyl-L-alanylglycyl-L-leucyl-;glycyl-L-alpha-glutamyl-L-prolyl-L-prolyl-L-prolylglycyllysyl-L-prolyl-L-alanyl-L- alpha-aspartylL-alpha-aspartyl-L-alanylglycyl-L-leucyl-L-valine
PubChem: CID 108101
AKA: Thymosin Beta 4
Molecular Formula: C212H350N56O78S
Molecular Weight: 4963.506 g/mol
PubChem: CID 16132341
CAS Number: 77591-33-4
Potential of BPC-157 & TB-500 Peptide Blend in Wound Repair
BPC-157 and TB-500 have been well studied to promote wound healing although they use different biochemical pathways. However, research has shown that in combination, the two molecules exhibit synergistic effects in the healing process.
BPC-157 & TB-500 peptide blend – Cellular Migration
Fibroblasts and immune cells are crucial for the regulation and execution of successful healing of wounds. Both fibroblasts and immune cells migrate to the site of tissue injury whereby fibroblasts promote the formation of an extracellular matrix. The movement of these cells is dependent on the protein axin. BPC-157 and TB-500 influence wound healing through their regulation of axin protein. BP-157 is known to promote the transcription of axin gene and thereby increase the expression of the protein. TB-500 enhances the functionality of axin by associating with it. Axin thus gets localized to those areas where it is most crucial to form axin filaments which are further required for fibroblast and immune cell migration. Thus, BPC-157 & TB-500 peptide blend synergize to enhance the expression and function of actin and promote faster migration of cells to the areas of damage.
Growth Hormone is involved in the Synergism
Growth hormone is a key mediator in the synergism between BPC-157 and TBS-500 for effective wound healing. Both molecules interact with the growth hormone during the healing process. BPC-157 induces a higher production of growth hormone receptors on the surface of fibroblasts thereby increasing the lifespan of these cells. This in turn promotes the regeneration of soft tissues. TB-500 further improves the localization of actin and filament formation. It ensures that the actin reserve is well maintained for use by fibroblasts in their extended lifespans. Thus, the combination of BPC-157, TBS-500, collagen and growth hormones can form an effective alternate treatment regimen for faster wound healing with the potential to replace the existing treatment of choice. Only buy BPC-157 & TB-500 (blend) if you are a licensed researcher.