Mod GRF 1-29 & GHRP-2 Blend (10mg)

(31 customer reviews)

$84.00

Mod GRF 1-29 & GHRP-2 blend is Synthesized and Lyophilized in the USA.

Discount per Quantity

Quantity 5 - 910 +
Discount 5%10%
Price $79.80$75.60
Orders over $200 receive:
FREE - 30ml bottle of bacteriostatic water
(Required for reconstitution)
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SKU: Mod-GRF-1-29-GHRP-2-10mg Category:

Description

Modified GRF 1-29 & GHRP-2 Peptide Blend

Mod GRF 1-29 is a synthetic peptide analog of Growth Hormone Releasing Hormone (GHRH). It is a modified version of the first twenty-nine amino acids of the naturally occurring GHRH. This modification has been suggested to provide better stability and also evade metabolic clearance. It may lead to natural growth hormone production and increased levels of IGF-1 (Insulin-Like Growth Factor-1).[1]

GHRP-2 (Growth Hormone Releasing Peptide) is a second-generation GHRP, a type of Growth hormone Secretagogues. Other examples include GHRP-6, Ipamorelin, Hexarelin, etc. It has been studied for its potential to increase growth hormone production by amplifying the natural Growth Hormone-Releasing Hormone (GHRH) signal transduction pathway, and potentially suppressing the action of Somatostatin.[2] GRHP-2 has been suggested to hold a lesser effect on gastric motility.

Various analogs of growth hormone have been studied regarding their potential to increase endogenous production of the hormone. Still, none of them have been suggested to induce significant impact, primarily attributed to a purported short-term activity. However, Modified GRF (1-29), or Mod GRF (1-29) is a growth hormone analog that may have the potential to provide a prolonged increase in the peak and basal growth hormone levels. Like the natural Growth Hormone Release Hormone (GHRH), this peptide appears to act by binding to the growth hormone-releasing hormone receptors occurring in the pituitary gland. A negative feedback mechanism by Somatostatin appears to regulate any effect of Mod GRF (1-29) on growth hormone release. It may prevent excessive levels of hormone secretion and sustain a natural pattern of growth hormone concentration.

Modified GRF 1-29 Specifications

Molecular Formula: C152H252N44O42

Molecular Weight: 3367.95 g/mol

Sequence: H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2

GHRP-2 Specifications

Molecular Formula: C45H55N9O6

Molecular Weight: 817.9 g/mol

Sequence: H-D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2

Mod GRF 1-29 & GHRP-2 Blend Research

Researchers suggest that GHRP-2 acts by releasing a pulse of growth hormone, and Mod GRF (1-29) appears to release and amplify this pulse.[3]

Mod GRF (1-29) & GHRP-2 and Body Mass
Increasing muscle growth is one of the widely studied potentials of Growth Hormone Analogs.[4] They appears to increase muscle growth by increasing the size of already present muscle cells and increasing the number of muscle fibers. Being both growth hormone analogs, Mod GRF (1-29) and GHRP-2 may exhibit impact on growth hormone production and muscle cell activities.

Mod GRF (1-29) & GHRP-2 and Tissue Repair
An increase in growth hormone levels may support cellular repair and reduce cellular damage. It may enhance collagen production and fibroblast proliferation, which in turn supports repair activities in damaged tissues. In addition, studies in these peptides suggest they may help to mitigate oxidative stress.

Mod GRF (1-29) & GHRP-2 and Blood Sugar Level Regulation
GHRH analogs appear to play a role in blood-glucose-level regulation by enhancing cell survival and cellular proliferation of pancreatic islets in diabetes. They appear to up-regulate the release of Insulin-Like Growth Factors.[5] The researchers report “short term [exposure] of GHRH [appeared to reverse] age-related decreases in GH and IGF-I.” Studies have suggested a profound increase in islet size and insulin expression in rats under the influence of GHRH. In addition to the high blood sugar levels that characterize diabetes, dyslipidemias may also significantly increase the morbidity associated with diabetes. Research in GHRH analogs has suggested its potential reducing in the triglyceride-rich lipoproteins in the blood.

Mod GRF (1-29) & GHRP-2 and Bone Mineral Density
GHRH analogs, through their Insulin-Like-Growth Factor 1(IGF-1) mediated actions may enhance proliferation, differentiation, and survival of bone-forming cells.[6] Research into the activities of this peptide blend has indicated some potential to increase bone mineral density and mineralization. Studies in the peptide blend also suggests that it may play a protective role against hormone-induced bone loss, such as that seen in osteoporosis.

Mod GRF (1-29) & GHRP-2 and Cardioprotection
Various studies have suggested the role of GHRH analogs in promoting the repair of cardiac tissue, improvement in heart ejection fraction, and reducing the infarct size following myocardial infarction.[7] The scientists suggest that “GHRH-A improved cardiac diastolic hemodynamics, including end-diastolic pressure, end-diastolic pressure–volume ratio, and stroke work, compared to placebo.” Some laboratory studies reported a decrease in infarct size and attenuation of cardiac hypertrophy in mice. It also appears to protect the myocardial tissue from oxidative stress induced by reactive oxygen species following ischemia.

Disclaimer: The products mentioned are not intended for human or animal consumption. Research chemicals are intended solely for laboratory experimentation and/or in-vitro testing. Bodily introduction of any sort is strictly prohibited by law. All purchases are limited to licensed researchers and/or qualified professionals. All information shared in this article is for educational purposes only.

 

References

  1. Valcavi R, Jordan V, Dieguez C, John R, Manicardi E, Portioli I, Rodriguez-Arnao MD, Gomez-Pan A, Hall R, Scanlon MF. Growth hormone responses to GRF 1-29 in patients with primary hypothyroidism before and during replacement therapy with thyroxine. Clin Endocrinol (Oxf). 1986 Jun;24(6):693-8. doi: 10.1111/j.1365-2265.1986.tb01666.x. PMID: 3098458.
  2. Phung LT, Inoue H, Nou V, Lee HG, Vega RA, Matsunaga N, Hidaka S, Kuwayama H, Hidari H. The effects of growth hormone-releasing peptide-2 (GHRP-2) on the release of growth hormone and growth performance in swine. Domest Anim Endocrinol. 2000 Apr;18(3):279-91. doi: 10.1016/s0739-7240(00)00050-3. PMID: 10793268.
  3. Waelbroeck M, Robberecht P, Coy DH, Camus JC, De Neef P, Christophe J. Interaction of growth hormone-releasing factor (GRF) and 14 GRF analogs with vasoactive intestinal peptide (VIP) receptors of rat pancreas. Discovery of (N-Ac-Tyr1,D-Phe2)-GRF(1-29)-NH2 as a VIP antagonist. Endocrinology. 1985 Jun;116(6):2643-9. doi: 10.1210/endo-116-6-2643. PMID: 2859987.
  4. Sinha DK, Balasubramanian A, Tatem AJ, Rivera-Mirabal J, Yu J, Kovac J, Pastuszak AW, Lipshultz LI. Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males. Transl Androl Urol. 2020 Mar;9(Suppl 2):S149-S159. doi: 10.21037/tau.2019.11.30. PMID: 32257855; PMCID: PMC7108996.
  5. Corpas E, Harman SM, Piñeyro MA, Roberson R, Blackman MR. Growth hormone (GH)-releasing hormone-(1-29) twice daily reverses the decreased GH and insulin-like growth factor-I levels in old men. J Clin Endocrinol Metab. 1992 Aug;75(2):530-5. doi: 10.1210/jcem.75.2.1379256. PMID: 1379256.
  6. Dubreuil P, Abribat T, Broxup B, Brazeau P. Long-term growth hormone-releasing factor administration on growth hormone, insulin-like growth factor-I concentrations, and bone healing in the Beagle. Can J Vet Res. 1996 Jan;60(1):7-13. PMID: 8825987; PMCID: PMC1263793.
  7. Rieger AC, Bagno LL, Salerno A, Florea V, Rodriguez J, Rosado M, Turner D, Dulce RA, Takeuchi LM, Kanashiro-Takeuchi RM, Buchwald P, Wanschel ACBA, Balkan W, Schulman IH, Schally AV, Hare JM. Growth hormone-releasing hormone agonists ameliorate chronic kidney disease-induced heart failure with preserved ejection fraction. Proc Natl Acad Sci U S A. 2021 Jan 26;118(4):e2019835118. doi: 10.1073/pnas.2019835118. PMID: 33468654; PMCID: PMC7848727.
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This product is strictly for research/laboratory use only.  Human or animal use and/or consumption is strictly prohibited by law.  Only qualified and licensed professionals should handle these products.  Any information found on Biotech Peptides is strictly for educational purposes only.  Refer to our terms and conditions for more details.

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Biotech Peptides

31 reviews for Mod GRF 1-29 & GHRP-2 Blend (10mg)

  1. Genesis Ashley

    Was very unhappy with where I was getting my peptides from until I found Biotech. Keep up the good work.

  2. Colson Monroe

    I’ve now ordered 4 times and the consistency is definitely there. The research peptide industry is a bit dodgy to be honest but I really have trust in Biotech. I havent been let down yet. Thank you!!!

  3. Wesley Thatcher

    great product and great shipping times

  4. Paul Levine

    wow! very fast delivery.

  5. Lyle Hope

    I couldn’t have asked for a smoother process. The product got here sooner than expected, it was properly packaged, and I’m ecstatic with the results. I’ll be a customer for as long as these guys are around!

  6. Lathan Ellis

    Defintely ordering again

  7. Adam Stachowiak

    Have ordered from them a few times now. Have shown the same consistency in service and quality of the product!

  8. Joe Samaniego

    I am based in Canada. Was kind of worried as I have had issues when using companies from the states. the peptides tend to get ruined and damaged and it becomes a whole ordeal. They sold me with their policy about refunding or resending products if anything was to go wrong. Luckily nothing went wrong with this batch. I’m still in disbelief. Will definitely buy again and if anything happens in the future will see if they stand by their word.

  9. Cari Morales

    Everything came as advertised. No missing vials, no broken products. My only complaint is I wish they were packaged differently.

  10. Allie Thompson

    They made everything pretty convenient! Got all my products in except one. They told me to check in a few days cause it was out of stock.

    update: The adipodite came in approximately a week after the initial package.

  11. Yu Wu

    I accidentally bumped into this website. Have been a faithful buyer ever since. Better than the rest

  12. Chirag Bharati

    Very good, was able to send their stuff all the way to India, This is amazing as it is hard to send overseas. Have had a horrible experince before. they took good care of everything and packed it safly.

  13. Anthony Hinojosa

    I’ve ordered in bulk with them on and off for the past year. I switch off them and another company when either are out of stock of the peptides I need. I’m noticing better results with the biotech peptides. Just wish they were able to keep in stock more frequently then they are out of stock.

  14. Andrew Sinclair

    They are great and sending out frequent promo codes or discounts. Sale options aren’t half bad either.

  15. Trey Philips

    Got everything delivered on time and in perfect condition!

  16. Mila Atken

    They charged me twice the last time I ordered. Thankfully they are eays to get in contact with so Taylor was able to sort the issue out. I guess I may have double clicked when finishing up so their system messed up with payment. Whatever the case, it was handled quickly and already saw my refund. Refund took a few days per usual.

  17. Rufus Otokar

    May have been a glitch in their system but it was not letting me purchase anything. Anytime I tried to buy from my cart i’d get an error page. Checked back a few hours later as it was getting frustrating anf the problem seemed to clear up. Got my order in and it should be here on time.

  18. Annie Haas

    Danny has helped me find lost pacages and then proceded to send me a new one anyway. Best service!

  19. Liam Anderson

    Helpful team! Jamie was the representative I dealth with and they were able to fix a little problem I had with my order.

  20. Justin Garcia

    Products that are both safe and clean. The most effective peptides I’ve found thus far. The only company I’ll ever do business with will be this one. Their blog page is also a excellent source for more information

  21. Sue Gy

    Noticed one of my peptides was not performing as it should and I contacted them as I assumed that with the summer heat approaching the temp may have affected the peptide. They were able to send me a new batch of vials with no issues or extra charges.

  22. Shari Ishi

    Peptides came in great condition. I was worried about the heat and travel time but peptides check out!

  23. Brad Bradshaw

    The peptides were in excellent condition, and they even included a complimentary bottle of bacteriostatic water. It was a pleasant surprise to see that they also provided same-day shipment!

  24. Issac Green

    Prices are a bit high, not gonna lie, especially with the economic situation nowadays, but they are still priced better than some other places.

  25. Harlan Haws

    This blend produced amazing spikes in GH levels in the research I conducted.

  26. Khan F

    Couldn’t think of a better supplier, honestly. Every time someone asks me, I always recommend Biotech

  27. Jet Peveto

    Their CS is very helpful whenever you have to ask questions. They are very nice and well-trained and they always know how to help. Very reliable company and service

  28. Rick Rufus

    The best place to buy in bulk

  29. Tony Schmidt

    Everyone in my lab has switched to Biotech Peptides in last year or so. They have great quality products and affordable sales and offers, especially when buying in bulk

  30. Loni Grant

    Out of all the suppliers I bought from, you have the best quality and the best priced blends

  31. Walden Harlan

    This is my first time ordering from them and everything went smoothly. It’s your standard process but products came in much quicker than I’m used to.

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