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Sermorelin & Ipamorelin Blend (10mg)
HPLC - Sermorelin & Ipamorelin Blend
Mass Spectrometry - Sermorelin & Ipamorelin Blend
Certificate of Analysis - Sermorelin & Ipamorelin Blend

Sermorelin & Ipamorelin Blend (10mg)

(41 customer reviews)

$81.00

Sermorelin & Ipamorelin Blends are Synthesized and Lyophilized in the USA.

Discount per Quantity

Quantity 5 - 910 +
Discount 5%10%
Price $76.95$72.90
Orders over $200 receive:
FREE - 30ml bottle of bacteriostatic water
(Required for reconstitution)
FREE - USPS priority shipping
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SKU: Sermorelin-Ipamorelin-10mg Category:

Description

Sermorelin Specifications

Molecular Formula: C149H246N44O42S

Molecular Weight: 3357.9 g/mol

Sequence: Tyr-Ala-Asp-Ala-lle-Phe-DL-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2

PubChem: CID 16129620

CAS Number: 86168-78-7

Reconstitution: Required

Ipamorelin Specifications

Molecular Formula: C38H49N9O5

Molecular Weight: 711.85 g/mol

Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH2

PubChem: CID 20754357

CAS Number: 170851-70-4

Reconstitution: Required

What is the Sermorelin & Ipamorelin Blend?

Combinatorial use of Sermorelin & Ipamorelin peptides can possibly induce the maximal release of growth hormone. Sermorelin is a newly developed growth hormone-releasing hormone (GHRH) analog. It not only appears to maintain the benefits of natural GHRH but also may help to avoid a few undesirable effects. Sermorelin may be a better alternative than GHRH in its mechanism of action, as it appears to act via a negative feedback mechanism. This action typically means that production will be automatically ceased in the case of excess. This process would reduce the adverse effects of GH excess in the body.

Similarly, Ipamorelin is the most specific and targeted analog of ghrelin/growth hormone secretagogue according to recent studies.[1] Researchers note that “ipamorelin is the first GHRP-receptor agonist with a selectivity for GH release similar to that displayed by GHRH. The specificity of ipamorelin makes this compound a very interesting candidate for future clinical development.” It appears to be a selective peptide agonist of the ghrelin hormone. Its reported primary action is to increase the circulating levels of GH in both animals and humans. Upon combination, these peptides may act synergistically to induce maximal production of the growth hormone. The synergy would amplify the benefits of GH on brain health, muscle growth, cardiac balance, and metabolism.

Sermorelin has been reported by researchers to have multiple beneficial effects on different body systems. Research suggests that Sermorelin may effectively reduce seizure activity in the body by activating GABA receptors.[2] Its negative feedback mechanism of action also makes it a potential preferred candidate over GH in growth disorders. The targeted influence of Sermorelin may bring about improved growth hormone effects on the heart.[3] A study conducted in pigs reported that the peptide decreases cell death of cardiomyocytes, promotes healing post-cardiac injury, angiogenesis, and may also subside inflammation.[4] It has been suggested to reduce the scar size by increasing extracellular matrix production. Newer studies have also suggested an improved diastolic function under the effect of Sermorelin. Recent findings highlight the presence of a variant of the ghrelin receptor in cardiac tissues.[5] Researchers note that “Although the mechanisms underlying the effects of ghrelin on the cardiovascular system have not been fully elucidated, some evidence suggests that its beneficial effects are mediated through both direct actions on cardiovascular cells and regulation of autonomic nervous system activity.” The variant form has been observed to regulate cardiac output. Therefore, using ghrelin and ghrelin analogs may reduce the risk of cardiac arrhythmias and promote healing after cardiac injury. Not only this, but Sermorelin use has now been advocated for its potential in valvular heart diseases and cardiac failure treatments.

Sermorelin & Ipamorelin peptide blends appear to have specific GH-related advantages. These effects are reported to be more pronounced in comparison with other GH-releasing peptides. When taken in combination, studies on both of these peptides report numerous potential benefits. These include increased bone density, improved mental wellness and clarity, and quicker recovery from workout injuries. Animal studies have suggested that in addition to cardiac wellbeing, Sermorelin may positively influence the central nervous system to improve sleep quality. This effect of Sermorelin on the sleep cycle is mediated via its production of orexin.[6] Orexin is a potent neurotransmitter with a proven effect on the sleep cycle. Adding to the fact that most of the healing and growth occurs during sleep, Sermorelin may play a two-way role in sleep disorders associated with defective growth.

Ipamorelin is another revolutionary discovery. It is not a hormone in itself. Instead, it appears to act by molecular mimicry of ghrelin, mainly triggering the pituitary gland to produce its natural growth hormones. This mechanism of action of Ipamorelin appears to eliminate the multitude of side effects that comes with the use of synthetic growth hormones. Ipamorelin has been suggested to influence the growth hormone effects selectively. It is mainly studied for its potential to increase bone density and bone mass. Ipamorelin has been commonly studied in HIV patients for strengthening their immune systems. It also has been reported to improve the health of skin, hair, and nails in experimental studies. Ipamorelin has been associated with improved bone health, insulin balance in diabetes, and bowel movement (especially post-surgery).

References

  1. Raun K, Hansen BS, Johansen NL, et al. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. 1998;139(5):552-561. doi:10.1530/eje.0.1390552.
  2. Tang S, Luo Z, Qiu X, et al. Interactions between GHRH and GABAARs in the brains of patients with epilepsy and in animal models of epilepsy. Sci Rep. 2017;7(1):18110. Published 2017 Dec 22. doi:10.1038/s41598-017-18416-5.
  3. Kanashiro-Takeuchi RM, Szalontay L, Schally AV, et al. New therapeutic approach to heart failure due to myocardial infarction based on targeting growth hormone-releasing hormone receptor. Oncotarget. 2015;6(12):9728-9739. doi:10.18632/oncotarget.3303.
  4. Bagno LL, Kanashiro-Takeuchi RM, Suncion VY, et al. Growth hormone-releasing hormone agonists reduce myocardial infarct scar in swine with subacute ischemic cardiomyopathy. J Am Heart Assoc. 2015;4(4):e001464. Published 2015 Mar 31. doi:10.1161/JAHA.114.001464.
  5. Tokudome T, Otani K, Miyazato M, Kangawa K. Ghrelin and the heart. Peptides. 2019;111:42-46. doi:10.1016/j.peptides.2018.05.006.
  6. Shepherd BS, Johnson JK, Silverstein JT, et al. Endocrine and orexigenic actions of growth hormone secretagogues in rainbow trout (Oncorhynchus mykiss). Comp Biochem Physiol A Mol Integr Physiol. 2007;146(3):390-399. doi:10.1016/j.cbpa.2006.11.004.
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Additional information

Brand

Biotech Peptides

41 reviews for Sermorelin & Ipamorelin Blend (10mg)

  1. Charlotte Wood –

    I didn’t have to once reach out to them because they haven’t given me a reason too. Everything from payment to shipping to quality has been excellent.

  2. August Gutierrez –

    Never had a problem. Products are always as described. Fast delivery

  3. Skye Gordon –

    This is my 3rd order. Very good

  4. Ozzy Kent –

    A really exceptional level of customer care for a product of this kind. Previously, I’d had to wait more than three weeks for peptides from a different provider, but these people were on another level.

  5. Kamari Clark –

    The products I’ve purchased from here have always arrived on schedule and have been of the highest quality.

  6. David Mooney –

    I never wanted to experiment with other companies as I was content with the one I was working with for the past few years. I was recommended this company and decided to bite the bullet and try them out. I am glad I did. Will be switching over to Biotech Peptides!

  7. Sheila Worley –

    The only bad thing I can ever think of when it comes to you is that I wish i got updates for when some peptides come back in stock.

  8. Ashley Peeples –

    Lovely staff

  9. Chad Anderson –

    good quality peptides

  10. Chang Liu –

    喜歡他們的網站。很棒的肽選擇 我很欣賞他們的銷售和他們發出的頻繁折扣

  11. Avani Ross –

    Good company. Have never had a broken vile in my peptides in the past year I have been buying with them.

  12. patrick R. –

    The peptides speak for themselves. Truly the best peptides I have come by thus far after a year of using them for my research.

  13. Jason F. –

    Products came in one peice. No breaks or anything.

  14. Jazz White –

    Very pleased that their storage life is long if you store them properly. Have had issues with peptides from other companies where even when you follow exact directions they still were not usable after a few weeks.

  15. Trever Chan –

    Great options, peptides are always stocked up as well.

  16. Adan Corral –

    Peptides are always pure and of the highest quality thanks to this well-known supplier. Every lab I deal with or any scientist I know that is interested in peptides I recommend Biotech to them.

  17. Tyrone Lee –

    As a result of going to Europe, we had a little delay in receiving our order. I’m pleased to say that the peptides were not damaged in the process of extraction. Well-protected in its box

  18. Cody Buring –

    Please please please change your carrier company. They are ruining your business

  19. Zion Fuller –

    I placed a bulk order and it arrived intact. All of it

  20. Omar Zahid –

    Only place I get peptides from. Peptides are always of the highest quality!

  21. Emel N –

    Compraré de nuevo. Estoy muy satisfecho con la calidad

  22. Macchio Rissone –

    This blend is so simple, yet so powerful and effective. My research turned out great. Thank you!

  23. Cam Turkzadeh –

    I love your blog. Very informative and accurate

  24. James Mann –

    Having been purchasing peptides from Biotech a while now and quality remains the same!

  25. Steven Reyes –

    I love the bac water that comes with the minimum order. I know it might not seem much for some, but small gestures like this are what makes the difference between suppliers, in my opinion

  26. Nate Boyd –

    They have the best peptides I’ve ever done research with

  27. Noah Ashman –

    I have never had any issues with them for almost 2 years now. Very good company

  28. Iram Nandolia –

    Found from a google search. Got a discount code after first order, peptides seem great

  29. Kevin Somoza –

    I am very impressed with this company and the quality of their products

  30. Issac Hamilton –

    If my next few orders go just as well as the first ones, I might switch to Biotech as my permanent supplier soon

  31. Edwin Gramajo –

    We have been working for them for a little over a year now. Best service we have ever had.

  32. Neeti Jain –

    They didn’t have a peptide I wanted in stock at some point, but I checked in a few days later and they had restocked. They sent me the package with same day delivery, free of extra delivery charges, to make up for being out of stock which was nice because they must have remembered me emialing about this or made a note of it. Never had that from any other peptide site.

  33. Niegel Guzman –

    Peptides came packaged nicely.

  34. Gerald Otems –

    Company speaks for itself. Great return time, nice customer service, and pretty good deals. Very up to date with their information but also stay to their word about replacing products if need be.

  35. Mckay Scates –

    Make my life so easy with the way they run things. I make big orders for out lab and I had contacted them months ago to set up some sort of deal since we were buying in bulk on a bi-weekly basis. We have never had an issue with them regarding shipping, price, products, or even just keeping their word to our deal. Of course when they’re out of stock of certain products (which has happened) they do call to let us know as well! But they have not yet left us wondering where our products were.

  36. Karl Hyatt –

    I like using Biotech peptide products rather than some other places. They get all the products to the buyer in a safe but quick manner. Feel like I have had less breaks or missing products with them than some other places I have shopped from in the past.

  37. Devynn Polivka –

    I think there was a glitch with the site. It kept adding products to my cart that I did not have. Left the site and came back the next day and didn’t have that problem.

  38. Shannon Koenig –

    Got a nice little discount for my first purchase

  39. Dalton Evans –

    Was recommended to them by my old lab professor. Very happy with the results in my project.

  40. Jonas Prater –

    Blend is great! Goes well with my research. Glad to see they have it in stock since my last supplier has been out of stock for a while now.

  41. Jeff Darnaby –

    Can’t complain much, wish their sales had more options however!

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