Fragment 176-191 & Mod GRF 1-29 & Ipamorelin Blend (12mg)

(23 customer reviews)


Discount per Quantity

5 - 95%$72.20
10 +10%$68.40
SKU: Fragment-176-191-Mod-GRF-1-29-Ipamorelin-12mg Category:


Fragment 176-191 SPECIFICATIONS

AKA: Frag 176-191

Molecular Formula: C78H125N23O23S2

Molecular Weight: 1817.1 g/mol

Sequence: Tyr-Leu-Arg-Ile-Val-Gin-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe

CAS Number: 66004-57-7

Reconstitution: Required


AKA: Modified GRF (1-29)

Molecular Formula: C152H252N44O42

Molecular Weight: 3367.95 g/mol

Sequence: H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2

PubChem: CID 56841945

CAS Number: 863288-34-0

Reconstitution: Required


Molecular Formula: C38H49N9O5

Molecular Weight: 711.85 g/mol

Sequence: Aib-His-D-2Nal-D-Phe-Lys-NH2

PubChem: CID 9831659

CAS Number: 170851-70-4

Reconstitution: Required

Potential of Fragment 176-191 & Mod GRF 1-29 & Ipamorelin Blend

Studies have proven that the highest output of growth hormone (GH) from the anterior pituitary gland can be attained through a combination of growth hormone-releasing hormone (GHRH) analog and agonist of growth hormone secretagogue receptor (GHSR). The combination of ipamorelin with modified GRF is one of the various combinations which help to achieve the above objective. Interestingly, more specific results can be achieved beyond the increase in GH synthesis through the refinement of the choice of GHRH analog, and GHSR agonist used.

Modified GRF, also an effective GHRH analog has effects beyond the improvement of GH release. It has benefited intestinal inflammation, wound healing, and cardiac function in animal models. The introduction of ipamorelin along with modified GRF triggers the highest expression of GH. Ipamorelin further improves bone growth and the stabilization of the cellular matrix. The above physiological outcomes are in addition to the improvement of bone development caused directly through increased GH release.

Research on Fragment 176-191 & Mod GRF 1-29 & Ipamorelin

The idea behind using a combination of these peptides is to have a potent HGH response minus all the side effects. Below is what research suggests about this peptide combination.

Improved Body Composition
The main benefit of this peptide blend is its ability to promote fat loss and increase muscle mass. The critical component among this peptide blend capable of achieving weight loss is the fragment 176-191. HGH fragment 176-191 is the main ‘lipolytic fragment.’ It acts on the beta-3 adrenergic receptors (ADRB3). This peptide leads to increased fat burning in fatty tissues and increases fat breakdown by triggering ‘thermogenesis’ (heat production) in skeletal muscles by acting on these receptors.
Researchers have noticed that knock-out mice without ADRB3 receptors cannot respond to the effects of fragment 176-191. Interestingly, researchers noticed that fragment 176-191 only led to weight loss in obese mice and did not affect lean mice. It led to a nearly 50% reduction in weight gain in obese mice noticed over three weeks.
Other elements of this blend, such as Mod GRF (1-29), improve body composition by increasing muscle mass. The increase in muscle mass is due to two mechanisms triggered by this peptide: muscle hypertrophy (increase in the size of muscle fibers) and muscle hyperplasia (increase in the number of muscle fibers).

Improved Bone and Joint Health
This blend can be useful in dealing with various bone and joint-related conditions associated with aging. These include conditions such as osteoporosis and joint osteoarthritis.
Researchers noticed that when HGH fragment 176-191 was used in conjunction with hyaluronic acid injections in conditions such as osteoarthritis, it could potentiate joint cartilage growth. The study noticed that using the peptide in animal models of osteoarthritis improved joint cartilage. The improvement was more marked when used in combination with hyaluronic acid.
In addition, peptides such as Mod GRF and Ipamorelin are proven to improve bone health by activating bone cells via GH-mediated pathways. The use of these peptides leads to increased activity, proliferation, and differentiation of bone-forming cells and leads to an increase in Bone Mineral Density (BMD). This is useful in conditions such as osteoporosis.

Anti-aging Effects
The levels of growth hormone decline sharply following teenage years and continue to decline even more rapidly after the 40s. The signs of aging are the direct consequence of declining levels of GH. A blend of GH stimulating peptides, such as this one, can stimulate the natural increase in GH levels. An increase in GH levels is associated with an improvement in cell proliferation due to telomere shortening and a reduction in cellular death due to a decline in processes such as oxidative stress.

Other Health Benefits
Other potential health benefits of this peptide blend include:
● Improved cardiovascular health and quicker recovery following Myocardial Infarction (MI)
● Improved gut health
● Improved healing following injury or surgery and better aesthetic outcomes following cosmetic surgery procedures
● Improved mental health and might be helpful in neurodegenerative diseases such as Alzheimer’s dementia and Parkinson’s disease
● Better overall health, energy, and vitality levels
● Mental well-being
● Better thyroid health
● Enhanced recovery following injury and post-workout

Research has shown that fragment 176-191, a synthetic GHRH agonist is a strong catalyst for catabolism of adipocytes. Hence it is now possible to bring about targeted lipolysis by including fragment 176-191 with ipamorelin and Mod GRF 1-29. It is way more effective than most of the GHRH agonists in the burning of fat and hence is popularly called a “lipolytic fragment.” Thus inclusion of fragment 176-191 improves fat metabolism on the premise of increased GH release and modifies physiological metabolism in favor of lean body mass.

All orders ship same day if placed by 2pm PST.  Synthesized and lyophilized in the USA.
This product is strictly for research/laboratory use only.  Human or animal use and/or consumption is strictly prohibited by law.  Only qualified and licensed professionals should handle these products.  Any information found on Biotech Peptides is strictly for educational purposes only.  Refer to our terms and conditions for more details.

Additional information


Biotech Peptides

23 reviews for Fragment 176-191 & Mod GRF 1-29 & Ipamorelin Blend (12mg)

  1. Damian Riley

    Great service

  2. Charlotte Flores

    User friendly site, easy navigation and fast service. Ordered before and will surely order again

  3. Damian Riley

    My colleague and I have now ordered from this company multiple times and we have always been thrilled with the service.

  4. Briar Castillo

    I have not received my order yet, but the ordering and shopping experience was really fast and easy

  5. Daniel Harris

    I’ve been ordering my research peptides from Biotech Peptides for about a year now and I’ve had nothing but positive experiences and great results. I’ve had concerns with the validity of products from other sellers, but after a year of ordering here, there’s a strong rapport and trust which is important in this type of market.

  6. Shay Paz

    Keep up the good work

  7. Drew Owen

    Thanks for the discount code!Q

  8. Patrick Pan

    Fantastic company, great doing business with them

  9. Anita Hayes

    Satisfied with this company so far, would appreciate better packaging!

  10. Mila Atken

    Very nice company

  11. Jocasta Hanson

    I like getting peptides from here. just wish the vials were a bit bigger.

  12. Charlie Kofi

    Even though I paid for regular shipping I still got the peptides in much faster than anticipated. Everything was in order and in great condition as well.

  13. Micheal Hudson

    Idk if it’s just me, but the site through a phone looks a bit weird and hard to place orders. Wish they’d come up with an app.

  14. Peter Casey

    I shared this company with all of my coworkers and now everyone has switched to BP for research and we all order in bulk. Keep it up!

  15. Mckenna Dean

    This is my first time ordering from them and I am really excited. Hopefully the products live up to the reviews and reputation

  16. David Hipple

    Thanks for the free bac waters!

  17. David Hipple

    Amazed that I found such a great find. Biotech has been my peptide provider since August and It is refreshing to work with such a profound establishment.

  18. Freddie Krugger

    ordering is pretty standard and easy and they sent out a discount code right after.

  19. Eric Venseti

    It was my first time purchasing peptides with them. The reviews were too good to ignore. The peptides should be at my lab in the next day or two.

  20. k. ruth

    Found you guys from a google search. I decided to order a few peptides and was pleasently surprised about how smooth the check out process was. I recieved my peptides within a day. Most other places it would take days to get peptides shipped out.

  21. Robert Ehrig

    They gave me a full refund when my package went missing and I was no longer in need of the peptides.

  22. Ben Walker

    Found them from a google search. Have been looking for this peptide as other places are out. Glad I found it and they seem to have some peptides I have never heard of so that’s a plus.

  23. Autsin Menendez


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