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CJC-1295 & Ipamorelin & GHRP-2 Blend
HPLC - CJC1295 & Ipamorelin & GHRP-2 Blend
Mass Spectrometry - CJC1295 & Ipamorelin & GHRP-2 Blend
Certificate of Analysis - CJC1295 & Ipamorelin & GHRP-2 Blend

CJC-1295 & Ipamorelin & GHRP-2 Blend (9mg)

(64 customer reviews)

$80.00

CJC-1295 & Ipamorelin & GHRP-2 blend is Synthesized and Lyophilized in the USA.

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Quantity 5 - 910 +
Discount 5%10%
Price $76.00$72.00
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SKU: CJC-1295-Ipamorelin-GHRP-2-6mg Category:

Description

CJC-1295 & Ipamorelin & GHRP-2 Peptide Blend

CJC-1295 is a Growth Hormone secretagogue, also known as DAC: GRF. It is an advanced version of GHRH (1-29), synthetically developed with the intention of producing better pharmacokinetics, potentially increasing Growth Hormone levels and Insulin-Like Growth Factor 1 (IGF-1). According to research, it exhibits the potential to increase the production level of Growth Hormone anywhere from 200-1000%. Moreover, the research developers commented that CJC-1295 may increase “mean plasma IGF-I concentrations by 1.5- to 3-fold.”[1] This apparent rise in growth hormone level has been reported to persist for about 6-8 days under study conditions. A longer half-life would ensure the increased level of growth hormone production even beyond the initial introduction of the peptide.
Ipamorelin is a pentapeptide and considered a Growth Hormone Secretagogue (GSH). It has been reported by researchers to exhibit similar action as Growth Hormone Releasing Peptides (GHRPs) and reportedly mimics the naturally occurring hunger hormone, ghrelin.[2] It has been researched within the context of improving vitality and health, and may exhibit potential anti-aging action on skin and organs. One of the most studied potential implications of Ipamorelin is on its selectivity and lack of action on the release of other hormones such as cortisol, prolactin, and aldosterone.
GHRP-2 (Growth Hormone Releasing Peptide) is a 2nd-generation Growth Hormone Secretagogue (GSH).[3] It appears to enhance the concentration of Growth Hormone in test models via up-regulating the natural Growth Hormone Releasing Hormone signal transduction pathway. It may also potentially suppress the impact of Somatostatin. Studies have suggested that GHRP-2 may be introduced in high concentrations to test models, without inducing desensitization which is considered inherent with other GHRPs. It may help maintain a high effective concentration of Growth Hormone in the blood. Studies also suggest that the peptide may stimulate appetite. According to scientists, “GHRP-2, like ghrelin, increases food intake, suggesting that GHRP-2 is a valuable tool for investigating ghrelin effects on eating behavior.”[3]

CJC-1295 Specifications

Molecular Formula: C152H252N44O42

Molecular Weight: 3647.954 g/mol

Sequence: H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-Lys(Mal)-NH2

PubChem: CID 56841945

Reconstitution: Required

Other: DOES NOT CONTAIN DAC

Ipamorelin Specifications

Molecular Formula: C38H49N9O5

Molecular Weight: 711.85 g/mol

Sequence: Aib-His-D-2Nal-D-Phe-Lys-NH2

PubChem: CID 9831659

CAS Number: 170851-70-4

Reconstitution: Required

GHRP-2 Specifications

Molecular Formula: C45H55N9O6

Molecular Weight: 817.9 g/mol

Sequence: H-D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2

PubChem: CID 6918245

CAS Number: 158861-67-7

Reconstitution: Required

CJC-1295 & Ipamorelin & GHRP-2 Blend Research

The synergistic combination of CJC-1295, Ipamorelin, and GHRP-2, may potentially exhibit an amplifier and booster effect on Growth Hormone (GH) production. This combination may enhance GH levels through increasing the activity of cells that secrete GH (Somatotrophs) along with increasing the strength of the pulse of GH. Altogether, it may possibly induce a steady and enhanced release of GH.

CJC-1295 & Ipamorelin & GHRP-2: Muscle Mass
The primary context of research on this blend focuses on its potential to promote an increase in muscle mass, along with an apparent increase in cellular proliferation and tissue growth.[4] One study which involved murine models with a gene ablation of GHRH (referred to as GHRHKO), commented that the introduction of CJC-1295 might exhibit tissue-specific action. When GHRHKO murine models were introduced to CJC-1295 at intervals of 24 hours, they appeared to exhibit normal weight and length. However, when the intervals were increased to 48 and 72 hours, the murine models appeared to have reached a higher body weight and length compared to those that were given a placebo, but they still did not achieve full growth normalization. In terms of bone growth, it appears that the femur and tibia lengths may have also achieved normal dimensions in the murine models introduced to the peptide every 24 and 48 hours, but not at 72 hours. Additionally, the relative lean mass and subcutaneous fat mass was found to maintain control levels in all groups associated with the peptide. Another observation the researchers made that stands out is that CJC-1295 may have led to an increase in total pituitary RNA and GH mRNA. This posits that there may have been a proliferation of somatotroph cells, which are cells in the pituitary gland that are considered to be responsible for producing growth hormone. This proliferation was further supported through immunohistochemistry images. The findings from this study suggest that more frequent introduction of CJC-1295 may maintain normal body composition and growth in GHRHKO murine models. However, its potential appears to be reduced when intervals are every 48 or 72 hours.

CJC-1295 & Ipamorelin & GHRP-2: Bone Density
These peptides have been studied in laboratory conditions within the context of various bone-related degenerative diseases such as osteoporosis. The consistent theory proposed in these studies was the potential positive impact of Ipamorelin on bone mineral density.[5] It has been hypothesized to act through GH-mediated pathways on the osteoblasts (bone-forming cells), possibly leading to increased proliferation, development, and differentiation of the osteoblasts. In one study, murine models were subjected to either Ipamorelin or a control substance. The progress of the murine models in relation to Ipamorelin’s possible action on bone mineral density was tracked in real-time using dual X-ray absorptiometry (DXA) at sites such as the femur and L6 vertebrae. Following the study period, the femurs of the murine models were analyzed using mid-diaphyseal peripheral quantitative computed tomography (pQCT) scans. The results seem to suggest that the peptide may have led to an increase in body weight and a possible rise in the total tibial and vertebral BMC (bone mineral content) when observed through DXA, compared to the control group. However, when the total BMC was adjusted for the increase in body weight, the researchers reported that there didn’t appear to be a significant change. An increase might have been observed in the tibial area bone mineral density (BMD, which is the ratio of BMC to area), but the total and vertebral area BMDs seem to have remained consistent. The pQCT measurements possibly indicated that the increase in the cortical BMC could be due to an expansion in the cross-sectional bone area, while the cortical volumetric BMD appears to have remained consistent. Both the femur and vertebrae L6 volumes may have seen an increase, but there didn’t seem to be a change in the volumetric BMDs. The observations potentially support the supposition that the rise in cortical and total BMC might be due to enhanced bone growth resulting in increased bone dimensions, while the volumetric BMD remained unchanged.

CJC-1295 & Ipamorelin & GHRP-2: Anti-aging
The natural production of GH declines with maturation. Declining GH levels appears to have widespread impact, and the maintenance or increase in declining levels of GH has been the primary focus of numerous research studies. Research has suggested that this combination of peptides exhibits some potential to counter age-related degenerative symptoms. The peptides may also reportedly improve skin elasticity by promoting the synthesis of collagen. This blend of peptides may improve cellular turnover and prevent free radical damage to the tissues by reducing oxidative stress. More specifically, research suggests that GHRP-2 in particular may exhibit antioxidative potential. Researchers report that GHRP-2 exhibits a possible affinity for CD36, which is posited to be a scavenger receptor for oxidized low-density lipoprotein (OxLDL). The peptide’s hypothetical binding capability may contribute to the possible hindering of cellular uptake of OxLDL, a complex that appears to have proatherogenic properties. In a study that involved murine models with a specific genetic profile (ApoE(-/-)), researchers introduced GHRP-2 to the models over a span of 12 weeks. The results appeared to suggest that GHRP-2 may lead to a rise in circulating IGF-I levels, potentially ranging between 1.2 to 1.6 times the baseline levels. Moreover, there was a reported reduction, by around 66%, in the levels of circulating interferon-gamma. While it seems that the introduction of GHRP-2 didn’t result in any significant changes in the area covered by atherosclerotic plaques, it possibly led to a reduction in the production of superoxide in the aorta, as suggested by dihydroethidium staining. Additionally, GHRP-2 may have caused a significant decrease, by about 92%, in the aortic gene expression of 12/15-lipoxygenase. It also appears to have reduced the aortic expression of both interferon-gamma and macrophage migration inhibitory factors. When examining aortic smooth muscle cells in culture, it was observed that GHRP-2 might counteract the generation of peroxides induced by OxLDL. It also seems to have prevented the down-regulation of the IGF-I receptor and possibly inhibited apoptosis. In the context of macrophages, GHRP-2 was hypothesized to reduce lipid accumulation when exposed to OxLDL.[6]

Further research on this peptide combination includes:
● An exploration of the blend’s potential in strengthening cardiovascular system and faster recovery following an ischemic injury (myocardial infarction)
● Possible impact in improving recovery and tissue repair following lab-induced injury
● Potential impact on immune function
● Potential impact on cognitive and memory function, particularly in relation to degenerative disorders such as dementia
● Potential impact in sleep cycles

References

  1. Teichman SL, Neale A, Lawrence B, Gagnon C, Castaigne JP, Frohman LA. Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. J Clin Endocrinol Metab. 2006 Mar;91(3):799-805. doi: 10.1210/jc.2005-1536. Epub 2005 Dec 13. PMID: 16352683.
  2. Raun K, Hansen BS, Johansen NL, Thøgersen H, Madsen K, Ankersen M, Andersen PH. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. 1998 Nov;139(5):552-61. doi: 10.1530/eje.0.1390552. PMID: 9849822.
  3. Laferrère B, Abraham C, Russell CD, Bowers CY. Growth hormone releasing peptide-2 (GHRP-2), like ghrelin, increases food intake in healthy men. J Clin Endocrinol Metab. 2005 Feb;90(2):611-4. doi: 10.1210/jc.2004-1719. PMID: 15699539; PMCID: PMC2824650.
  4. Alba M, Fintini D, Sagazio A, Lawrence B, Castaigne JP, Frohman LA, Salvatori R. Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse. Am J Physiol Endocrinol Metab. 2006 Dec;291(6):E1290-4. doi: 10.1152/ajpendo.00201.2006. Epub 2006 Jul 5. PMID: 16822960.
  5. Svensson J, Lall S, Dickson SL, Bengtsson BA, Rømer J, Ahnfelt-Rønne I, Ohlsson C, Jansson JO. The GH secretagogues ipamorelin and GH-releasing peptide-6 increase bone mineral content in adult female rats. J Endocrinol. 2000 Jun;165(3):569-77. doi: 10.1677/joe.0.1650569. PMID: 10828840.
  6. Titterington JS, Sukhanov S, Higashi Y, Vaughn C, Bowers C, Delafontaine P. Growth hormone-releasing peptide-2 suppresses vascular oxidative stress in ApoE-/- mice but does not reduce atherosclerosis. Endocrinology. 2009 Dec;150(12):5478-87. doi: 10.1210/en.2009-0283. Epub 2009 Oct 9. PMID: 19819949; PMCID: PMC2795722
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Biotech Peptides

64 reviews for CJC-1295 & Ipamorelin & GHRP-2 Blend (9mg)

  1. Hanna Byrne –

    Great company

  2. Harris Chase –

    I have shopped here several times and so far I have only had great experiences with this company

  3. Aurora Clark –

    I am very happy with my first order and will definitely order again. I got everything in when expected. They had a tracking number sent out and everything once the order was fully processed. I’d say They processed it within 12 hours of placing the order. Took another day to get the peptides in.

  4. Declan Walker –

    Their service is very prompt and reliable

  5. Finley Alvarez –

    I have always been one hundred percent satisfied with the product. I wouldn’t recommend any other company for anyone who wants to buy

  6. Sage Bennet –

    Amazing product and easy processing

  7. Harper Mendosa –

    Products are always just as good as they are advertised to be. I have never been let down so far

  8. Jaxon Ball –

    I’m a long time researcher and have ordered from a number of online suppliers in the USA. Biotech’s professionalism is unmatched. Fast shipping, credit cards accepted, and very well packaged. This may not seem like a big ordeal but I’ve previously received my orders from other suppliers in padded envelopes. How stupid do you have to be to ship such fragile goods in an envelope? My order was neatly packaged in a sturdy box.

  9. Joseph Yates –

    TWO THUMBS UP – JOSEPH YATES

  10. Sallow Samuel –

    I’m a big fan of the blends. So convenient vs individual vials.

  11. Roman Ford –

    They had lightening fast shipping and processing. I will say I wasn’t expecting the packaging. it came in great condition but I thought the peptides would be more secure in there.

  12. Theo Fensby –

    There was some sort of mixup and I received the wrong blend but customer service was quick to correct my order and had a replacement sent out the next day.

  13. Reuben Zouch –

    This is my favorite peptide stack at the moment. 10/10

  14. Leo Zelly –

    I was referred to Biotech by a friend, and Ive placed multiple orders in the last few months. No hiccups so far.

  15. Naomi Sanchez –

    Shipping was fast and the process was quick and easy

  16. Sherry Todd –

    Made me a happy customer! 🙂

  17. Viniamin Tokarchuk –

    I’m not crazy about your guys’ prices, but I guess the quality of products is worth it

  18. Drew Erhart –

    They are a wonderful new company. Been using them for about 5 months now and i’m satisifed with Biotech peptides service, quality, and attention to customers needs.

  19. Robert Marsh –

    My experience with Biotech has been great. Ordered them a few times already since I’ve discovered them. I do agree that they would benefit from different packaging.

  20. Jessica Miller –

    Was recommended to Biotech from a former colleague of mine. I was looking for a new peptide provider as the one I had previously donw work with began to sell low quality prodcuts that were effecting my research. I decided to give them a try. After a month they seem to be holding up to their advertisement of top tier quality. I have not dealth with the customer service yet but the payment process was also simple and easy as well. In short, I’ll keep testing them out but so far so good.

  21. Richard Wilson –

    It is always a pleasure doing business with Biotech Peptides. I have truly come to trust the company as they have constantly proven to be reliable, resourceful, knowledgable, and trustworthy. My company has been ordering from them on a weekly basis since June of 2021. I must say we have not ran into payment issues within this time. We have not had to contact them with regards to faulty or bad products. Orders have come in when quoted and deliverd in one piece.

  22. Steve Anderson –

    Packaging could be a bit better but in the past 15 months I have not had any vials break or come in ruined so I guess it seems to be working when it comes to my orders at least. Would appreiciate even more of a protective shipping style.

  23. terry stewart –

    This company is a gem for me. As I spend the majority of my day dealing with different companies and ordering products for our lab, they have never once given me an issue. They are readily avilable and easy to get a hole of so none of that waiting around and listening to an automated service with annoying music. Amazing team and amazing work ethic by the whole company.

  24. Teddy Griffon –

    Swicthed over to biotech recently and could not be happier with the peptides.

  25. Fred k. –

    Their team is always professional and ready with solutions!

  26. Henry Aaron –

    Peptides came in broken, it was frustrating to have to deal with getting new ones in. I dealth with Jamie and thankfully they had a new order sent out that same morning and they got it shipped overnight! Service wise great, transportation wise needs a new carrier.

  27. Patrick Haywood –

    Biotech Peptides has met the expectations of the lab I work for. We’ve developed a strong working connection with them since we purchase from them many times a week.

  28. John Feeny –

    Got some free bac water when I didn’t meet the minimum! Thanks!!

  29. Eric Collins –

    Maybe I dealth with somone who was knew, but the person I talked to a day ago didn’t know some stuff about the peptide we were talking about. Whatever the case, peptides are great but I’d ask for danni next time!

  30. Alex Kovacs –

    Fast response time!

  31. Parker stone –

    Peptides do what they’re supposed to. High quality for not that high of a price.

  32. Nate Gomez –

    Got free shipping and bac water with my first purchase!

  33. Brandon Ogdon –

    I swear by Biotech. Not only is it high quality but for the price its even better. Other places I know cost way more for the same quality of peptides.

  34. Alie Epple –

    The combinations of products here is impressive. Not a lot of places have this big of a variety. Also have a bunch of topical options!

  35. Nicol Horton –

    I think you guys need to had some cooling pack with the peptides since it’s summer!

  36. Jordan Weil –

    Research has has a noticable change since I started using Biotech peptides.

  37. Spencer Fuhr –

    Been a customer for about a year now. Never had a negative experince with them. Always great at sending out products on time and have the best quality around.

  38. Axle Kondzielawa –

    Site is easy to use and I like that my info is saved so check out is easy when it’s time to repurchase.

  39. Amy Chien –

    Blend is amazing, hard to find a good one this pure.

  40. Kyle Yang –

    Love the option of same day shipping. Ordered in the morning and had all my stuff by the end of the day!

  41. Diego Yong –

    It is clear to me that they invest a lot in training their CS, because those people have answers for every question one might have. They are very well trained, well-spoken and give you instant peace pf mind on any issue might appear along the way.

  42. Christian Allen –

    Jamie assisted me with ordering this peptide in bulk. Stress free process and got everything in on time with no extra hassle

  43. Vincent M. –

    Got all my orders in on time and got everything in great condition. No breaks or heat damage.

  44. Arnold Brooks –

    Selection of peptides have grown! Happy cause I had to buy a few from other sites as they didn’t have it. Now I get everything from here

  45. Cody Guo –

    They got super fast shipping even when you just get the standard option

  46. Jairo Madrigal –

    Straight to the point and fast e-mails. Don’t have to waste time going back and forth for days like I’ve experinced other places.

  47. Trent Brannigan –

    I got my peptides in the same day I ordered them! Came to find out if you order before a certain time they can potentially get it to you the same day so that was a nice surprise.

  48. Aaron Maynard –

    Waited a little longer than usual for these to restock, pushed my research schedule back.

  49. Nick Remsburg –

    Jamie was able to help me fix the address for my order. I had put the wrong address and qith two emails Jamie handled it!

  50. Gabe Coleman –

    Fast delivery time, I got an e-mail saying they were shipped out the day before it arrived.

  51. Ivan Lopez –

    Restocks are faster what they used to be.

  52. Chris Pereya –

    Ecstatic that they take many modes of payment, like to switch it up a lot and got frustrated when places took only a few specific cards.

  53. Joowon Lee –

    Had no issues getting them acorss country within 48 hours!

  54. Joey Auer –

    Delivery was on time! Just wish they had a better way to protect the peptides with the summer heat, just my personal prefrence.

  55. Micheal Calderon –

    Been with them going on over a year now! Happy they expanded and have more peptides as I love their peptides but had to find the others elsewhere and they’re not as high quality as the ones here.

  56. David Egen –

    Found them off a google search! Glad I did, peptides are reasonably priced compared to some other places right now!

  57. Turner Potts –

    Peptides got here in no time and I didn’t even pay for express shipping.

  58. Cam Gardner –

    My number one place to get Peptide from!

  59. Conor Chidester –

    Delivery was quick! Got it within 2 days with regular shipping

  60. Horace Bob –

    Peptides are doing wonders for my research. I do also love the pricing. Sometimes ai like to get a variety of peptides to work with but it can be tough with the high prices. Here I don’t mind at all! it’s reasonably enough for me!

  61. Ben Baker –

    The peptides did wonders for my research, good products do make a difference.

  62. Elle Scott –

    Always refreshing to have a person answer the phone and solve the issues rather than a machine.

  63. Micheal Jewell –

    Been with them for a year now, very happy with the service and the products! Purity always checks out.I also appreciate the discount codes they send out here and there to make it a better deal.

  64. Derek Ude –

    Best supplier out there right now.

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