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Mod GRF 1-29 & GHRP-6 Blend (10mg)

Mod GRF 1-29 & GHRP-6 (10mg)

(26 customer reviews)

$86.00

Mod GRF 1-29 & GHRP-6 blend is Synthesized and Lyophilized in the USA.

Discount per Quantity

Quantity 5 - 910 +
Discount 5%10%
Price $81.70$77.40
Orders over $200 receive:
FREE - 30ml bottle of bacteriostatic water
(Required for reconstitution)
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SKU: Mod-GRF-1-29-GHRP-6-10mg Category:

Description

Mod GRF (1-29) & GHRP-6 Peptide Blend

Mod GRF (1-29) & GHRP-6 are considered to be synergistic peptides. These peptides appear to increase the release of growth hormone (GH). The full structure of Growth Hormone Releasing Hormone (GHRH) contains 44 amino acids. Researchers have noticed that the first 29 amino acids (1-29) appear to contain the full biological activity of GHRH. This fraction is called Growth Hormone Releasing Factor (GRF 1-29).[1] GRF 1-29 appears to be biologically more active and has a longer duration of action as it evades metabolic clearance. Similarly, Growth Hormone Releasing Peptide-6 (GHRP-6) is under study as a stimulator of growth hormone release from the anterior pituitary gland.[2] According to the researchers: “These results provide evidence that the GH-stimulatory effects of GHRP-6 are achieved through activation of the PI second messenger system and thus support earlier findings that PKC and Ca2+ play central roles in mediating the effects of GHRP-6.”
A blend of Mod GRF (1-29) & GHRP-6 may lead to superior growth hormone release.

Modified GRF (1-29) Specifications

MOLECULAR FORMULA: C152H252N44O42

MOLECULAR WEIGHT: 3367.95 g/mol

SEQUENCE: H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2

 

GHRP-6 Specifications

MOLECULAR FORMULA: C46H56N12O6

MOLECULAR WEIGHT: 873.032 g/mol

SEQUENCE: L-histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysergamide, triacetate

 

Mod GRF (1-29) & GHRP-6 Research

Mod GRF (1-29) & GHRP-6 Peptides and Brain Function
Researchers have suggested that Mod GRF (1-29) and GHRP-6 exhibit potential within the context of neurodegenerative conditions. Studies in rodents reported that exposure to GHRP-6 appeared to help improve and solidify memory recall and learning behaviors, when compared to the rates of recall and learning in control groups. Research also suggests that growth hormone analogs, such as GHRP-6, may possibly assist spatial learning.[3] GHRP-6 has been associated with research in acute stroke, as it may provide improved aspects of brain function, such as spatial learning and problem-solving. Research suggests that GHRP-6 and other ghrelin analogs may induce greater blood supply to the brain, possibly inhibiting the development of new strokes and improve recovery following established strokes by reducing infarct size and promoting new tissue development. Mod GRF (1-29) & GHRP-6 blend may reduce apoptosis in brain cells, lower inflammation, and prevent structural and functional decline within the brain. Research is ongoing.

Mod GRF (1-29) & GHRP-6 Peptides and Cell Aging
The levels of growth hormone peak and then decline, and declining levels of growth hormone have been suggested by researchers to have an impact on cell-longevity and function. The synergy of Mod GRF (1-29) and GHRP-6 appear to naturally increase growth hormone levels and thereby might inhibit cell aging processes. This mitigation is considered a potential, due to the proposed ability of these peptides to boost cellular repair, reduce cellular damage due to oxidative stress, and reduce telomere shortening.

Mod GRF (1-29) & GHRP-6 Peptides and Tissue Repair
Mod GRF (1-29) & GHRP-6 in combination appears to increase tissue synthesis. GHRP-6 has been suggested by researchers to interact with CD36 receptors associated with angiogenesis, the growth of new blood vessels.[4] The researchers report that “In covalent competition binding studies with the GHRP-6 prototype hexarelin bearing a radiotracer, certain [aza-Glu]GHRP-6 azapeptides retained relatively high (2-27 μM) affinity for the CD36 scavenger receptor.” The growth of new blood vessels supports the development of new tissue and hastens repair to damages tissues. Animal study findings have suggested that GHRP-6 may thus impact tissue repair processes, increasing the synthesis of extracellular proteins like collagen, stimulating scar formation.

Mod GRF (1-29) & GHRP-6 Peptides and Heart Disease
Oxidative stress is considered to result in increased Reactive Oxygen Species (ROS) that may result in cardial damage. Research suggests that growth hormone analogs such as Mod GRF (1-29) and GHRP-6 may reduce the levels of oxidative stress and protect vulnerable but viable cells. These peptides may also improve cardiovascular function by building a stronger lipid profile, including increased triglyceride breakdown.

Mod GRF (1-29) & GHRP-6 Peptides and Muscle Cell Growth
Muscle growth is one of the most studied effects of growth hormones. Growth hormone analogs such as Mod GRF (1-29) & GHRP-6 have been studied for their potential to increase muscle mass via two different mechanisms: muscle hypertrophy and hyperplasia. Muscle hypertrophy results in increased muscle mass due to the increased size of already present muscle fibers. Muscle hyperplasia increases muscle mass by increasing the number of muscle fibers.

Mod GRF (1-29) & GHRP-6 Peptides and Bone Development
Growth hormone analogs appear to mediate action on bone mass via Insulin-Like Growth Factor 1 (IGF-1).[5] IGF-1 is suggested by researchers to promote the growth, differentiation, and survival of bone-forming cells. IGF-1 appears to improve the mineralization of bones and increases bone mineral density. In addition, it may also prevent the excessive hormone-induced loss of bones. This way, GH/IGF-1 interplay may improve bone quality and reduce the risk of conditions such as osteoporosis.

Disclaimer: The products mentioned are not intended for human or animal consumption. Research chemicals are intended solely for laboratory experimentation and/or in-vitro testing. Bodily introduction of any sort is strictly prohibited by law. All purchases are limited to licensed researchers and/or qualified professionals. All information shared in this article is for educational purposes only.

 

References

  1. Youn YS, Lee KC. Site-specific PEGylation for high-yield preparation of Lys(21)-amine PEGylated growth hormone-releasing factor (GRF) (1-29) using a GRF(1-29) derivative FMOC-protected at Tyr(1) and Lys(12). Bioconjug Chem. 2007 Mar-Apr;18(2):500-6. doi: 10.1021/bc060173z. Epub 2007 Jan 23. PMID: 17243755.
  2. Lei T, Buchfelder M, Fahlbusch R, Adams EF. Growth hormone releasing peptide (GHRP-6) stimulates phosphatidylinositol (PI) turnover in human pituitary somatotroph cells. J Mol Endocrinol. 1995 Feb;14(1):135-8. doi: 10.1677/jme.0.0140135. PMID: 7772238.
  3. Subirós N, Pérez-Saad HM, Berlanga JA, Aldana L, García-Illera G, Gibson CL, García-Del-Barco D. Assessment of dose-effect and therapeutic time window in preclinical studies of rhEGF and GHRP-6 coadministration for stroke therapy. Neurol Res. 2016 Mar;38(3):187-95. doi: 10.1179/1743132815Y.0000000089. Epub 2016 Apr 19. PMID: 26311576.
  4. Sabatino D, Proulx C, Pohankova P, Ong H, Lubell WD. Structure-activity relationships of GHRP-6 azapeptide ligands of the CD36 scavenger receptor by solid-phase submonomer azapeptide synthesis. J Am Chem Soc. 2011 Aug 17;133(32):12493-506. doi: 10.1021/ja203007u. Epub 2011 Jul 21. PMID: 21692501.
  5. Svensson J, Lall S, Dickson SL, Bengtsson BA, Rømer J, Ahnfelt-Rønne I, Ohlsson C, Jansson JO. The GH secretagogues ipamorelin and GH-releasing peptide-6 increase bone mineral content in adult female rats. J Endocrinol. 2000 Jun;165(3):569-77. doi: 10.1677/joe.0.1650569. PMID: 10828840.
All orders ship same day if placed by 12 PST.
This product is strictly for research/laboratory use only.  Human or animal use and/or consumption is strictly prohibited by law.  Only qualified and licensed professionals should handle these products.  Any information found on Biotech Peptides is strictly for educational purposes only.  Refer to our terms and conditions for more details.

Additional information

Brand

Biotech Peptides

26 reviews for Mod GRF 1-29 & GHRP-6 (10mg)

  1. Chris Dumitrescu –

    Easy people to work with, super fast shipping, testing of the products is pretty good for my small research setup, I would recommend them to anyone in the research field.

  2. Leah Jenner –

    Was purchasing somewhere else and recently swicthed over. No regrets so far!

  3. Taryn Alvarado –

    so far so good. no complaints, ordered on mondayand received the order wednesday afternoon.

  4. Emily Roy –

    Biotech Peptides has been my go-to supplier for about a year now following a string of bad luck with other suppliers. Their merchandise and service have met and exceeded my expectations.

  5. Daniel Salinas –

    Awsome quality and CS for a new company!

  6. Samatha Ross –

    Awesome i found a place so near to where my lab is! Shipping is just easy and fast. no worries about temp and if the peptides would go bad.

  7. Eunice Kim –

    Though they are not local, we received products the next day. I belive they’re based in california, we’re in Texas.

  8. Rick S –

    Happy they do international shipping! Have a hard time with some companies as they don’t want to deal with international shipping. It’s nice that they offer it. Heard the products are good! Once they’re in I’ll see for myself.

  9. Alex Noren –

    Satisifed with the transaction. I like the fact that my payment option is saved so that i’m in and out pretty quickly. Noticed my past purchaces are also listed so nice touch.

  10. Billy Mankin –

    Biotech employees are the best to deal with! Straight forward and to the point. Questions answered and problem fixed within 10 minutes of calling. Wonderful!

  11. Astrid Duncan –

    I have had a few broken vilas here and there while product was out in transit. They are gracious enough to resend the product if this happens and I am glad they do. In fact I got the new order within a day of reporting the incident.

  12. Ignatiy Leyton –

    Service proves time and time again to be the best. Taylor fixes any problems I have ever come across and has never had any trouble with doing so.

  13. Frank Mason –

    Have had a few broken vials and containers before. I always just shoot taylor an email letting them know when happened and how the package was receieved. They never ask me proof and send my order again no questions asked.

  14. Jake Thomas –

    Peptides came in when promised. Nothing looked broken or ruined during transit.

  15. chen roy –

    I’ve never had a problem with any thing I’ve purchased from Biotech. I can’t say enough good things about this company’s online ordering service and customer service.

  16. randy m. cadden –

    Found you from a google search, was searching for a new peptide source and stumbled upon your peptides. I’ve been working with them for the past 2 weeks and am amazed at the quality of them! Bonus is they’re priced great!

  17. Colby Holden –

    I was really satisfied with the goods. Because so many establishments are so hit-or-miss, I consider myself a lucky client. Every time Biotech comes through, there are no issues.

  18. Carlo dixon –

    Love the business, the customer service, and the product quality. Better packaging would be my sole recommendation! That could be in need of an upgrade.

  19. Marlo Tornel –

    I have no complaints so far. Everything went smoothly and I did not have to reach out.

  20. Nima Mofrad –

    This blend is also amazing for the half-life of the peptide. Everything is enhanced

  21. Jesus Gomez –

    Desde que uso BP mi investigación nunca ha sido mejor

  22. Raegan Renee –

    Love that they take many forms of payment! The card I use doesn’t always get accepted everywhere

  23. Steve Silvers –

    This company is highly efficient and as a person who hates wasting time I really appreciate that about them

  24. Rob Pepper –

    The company I represent is very pleased with Biotechs peptides, service, and prices. We have had issues before and they have been handled swiftly and without frustration. We as the consumer feel well taken care of and are looking forward to doing more business with Biotech.

  25. Collin brown –

    Have never let me down or disappointed me with the quality of peptides. This is my go to and I highly recommend trying it

  26. Garrete Pelton –

    Very good overall experience. The best I’ve had out of all the companies I’ve bought from so far

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