What is Mod GRF (1-29) & GHRP-6 Blend?
Mod GRF (1-29) & GHRP-6 are two synergistic peptides. These peptides work together to increase the release of growth hormone (GH).
The full structure of Growth Hormone Releasing Hormone (GHRH) contains 44 amino acids. Researchers have noticed that the first 29 amino acids (1-29) contain the full biological activity of GHRH. This fraction is called Growth Hormone Releasing Factor (GRF 1-29). GRF 1-29 is biologically more active and has a longer duration of action as it evades metabolic clearance.
Similarly, Growth Hormone Releasing Peptide-6 (GHRP-6) is a potent stimulator of growth hormone release from the anterior pituitary gland. Also, it is a potent agonist of ghrelin and growth hormone receptors.
Using a blend of Mod GRF (1-29) & GHRP-6 leads to superior growth hormone release and better outcomes than using either of these peptides alone.
Modified GRF (1-29) Specifications
MOLECULAR FORMULA: C152H252N44O42
MOLECULAR WEIGHT: 3367.95 g/mol
CAS NUMBER: 863288-34-0
PUBCHEM: CID 56841945
MOLECULAR FORMULA: C46H56N12O6
MOLECULAR WEIGHT: 873.032 g/mol
CAS NUMBER: 87616-84-0
SEQUENCE: L-histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysergamide, triacetate
PUBCHEM: CID 9919153
Research on Mod GRF (1-29) & GHRP-6
1. Brain Health
Mod GRF and GHRP-6 can help improve mental health and improve neurodegenerative conditions. This could be particularly useful in conditions such as Alzheimer’s and Parkinson’s disease. Also, it improves overall mental well-being and vitality and can be used in conditions such as depressive disorders.
Additionally, GHRP-6 could help with memory improvement and better learning. Studies in rodents have identified that using GHRP-6 in rodents can help retain more memories and aid in turning short-term memories into long-term memories. Research also suggests that GH analogs, such as GHRP-6, can assist spatial learning. GHRP-6 could be useful in situations such as acute stroke. It improves the functional aspects of brain function, such as spatial learning, problem-solving, and creating thinking.
Research suggests that using GHRP-6 and other ghrelin analogs can improve the supply of blood to the brain. This prevents the development of new strokes and can improve recovery following established strokes by reducing infarct size and promoting new tissue development. Mod GRF (1-29) & GHRP-6 blend could help reduce apoptosis in brain cells, lower inflammation, and prevent age-related structural and functional decline in brain function.
2. Anti-Aging Properties
The levels of growth hormone peak during the early teenage years and decline after that. The aging process is a direct consequence of declining levels of growth hormone. Many anti-aging treatments and processes aim to naturally increase the levels of growth hormones in the body.
The synergy of Mod GRF and GHRP-6 function to naturally increase growth hormone levels and thereby reverse the aging processes. This reversal is mostly due to the ability of these peptides to boost cellular repair, reduce cellular damage due to oxidative stress, and reduce telomere shortening.
3. Triggers Wound Healing
Mod GRF (1-29) & GHRP-6 combination increases tissue synthesis and promotes wound healing. GHRP-6 interacts with CD36 receptors known to promote angiogenesis, which is the growth of new blood vessels. The growth of new blood vessels in wounds improves wound healing. Animal studies have shown that GHRP-6 improves wound closure, increases the synthesis of extracellular proteins like collagen, and stimulates scar formation. This ability of this peptide blend can be used in clinical practice to achieve superior aesthetic outcomes in cosmetic surgeries.
4. Reduces the Risk of Heart Disease
Oxidative stress results in increased Reactive Oxygen Species (ROS) that damage the heart tissues and can result in heart damage. Research suggests that GH analogs such as Mod GRF and GHRP-6 can reduce the levels of oxidative stress, lower the risk of heart attacks, and protect vulnerable but still viable cells. These peptides can also improve cardiovascular health by promoting a healthy lipid profile, including increased triglyceride breakdown.
5. Muscle Growth
Muscle growth is one of the most uses growth hormones. The growth hormone analogs such as Mod GRF (1-29) & GHRP-6 can increase muscle mass by two different mechanisms: muscle hypertrophy and hyperplasia. Muscle hypertrophy results in increased muscle mass due to the increased size of already present muscle fibers. Muscle hyperplasia increases muscle mass by increasing the number of muscle fibers. Therefore, growth hormone analogs can be used as performance-boosting supplements.
6. Bone Development
Growth hormone analogs mediate many of their effects on bone mass via Insulin-Like Growth Factor 1 (IGF-1). IGF-1 promotes the growth, differentiation, and survival of bone-forming cells. IGF-1 improves the mineralization of bones and increases bone mineral density. In addition, it also prevents the excessive hormone-induced loss of bones. This way, GH/IGF-1 interplay improves bone quality and reduces the risk of conditions such as osteoporosis.
To conclude, mod GRF and GHRP-6 blend can have various clinical and biological effects. This blend increases the levels of the GH/IGF-1 axis. It has cellular proliferating and cytoprotective activities. This blend has protective effects against cellular damage resulting from increasing inflammation and oxidative stress. Moreover, this blend increases cellular proliferation and improves healthy tissue healing.