Gonadorelin (GnRH) (10mg)

(22 customer reviews)

$77.00

Discount per Quantity

QuantityDiscountPrice
5 - 95%$73.15
10 +10%$69.30
SKU: Gonadorelin-10mg Category:

Description

What Is Gonadorelin peptide?

Gonadorelin (GnRH) is a decapeptide gonadotropin-releasing hormone agonist. It stimulates the synthesis and release of luteinizing hormone and follicle-stimulating hormone. It is used in human medicine to treat infertility, irregular menstrual cycles, and hypogonadism. It is also used as a diagnostic tool to assess pituitary function. Ongoing research has uncovered potential uses for gonadorelin in treating breast, prostate, and Alzheimer’s disease.

SPECIFICATIONS

AKA: Growth Hormone Releasing Factor, Somatocrinin, Somatoliberin

Sequence: Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly

Molecular Formula: C55H75N17O13

Molecular Weight: 1182.311 g/mol

PubChem: 638793

CAS Number: 9034-40-6

Reconstitution: Required

Gonadorelin Research

Gonadorelin Research and Breast Cancer Prevention
Studies show that the higher the lifetime exposure to estrogen, the more likely a woman will develop breast cancer. Women who start menstruating at a young age, start estrogen-based contraceptives, start hormone replacement therapy during menopause, or have late-onset menopause are at risk of developing breast cancer. Fortunately, with oral contraceptives, your risk decreases when you stop taking the pill, and eventually, the increased risk returns to baseline. Of course, contraception is a double-edged sword because its use increases the risk of breast cancer but reduces the risk of ovarian cancer.
Some breast cancer cells require estrogen to grow, and minimizing estrogen production or blocking estrogen receptors is an established method for treating certain forms of breast cancer. Gonadorelin’s studies show that it can be used to control ovarian cancer Estrogen production and its potential to prevent breast cancer. This concept is based on the idea that some women are at increased risk of developing breast cancer in the postmenopausal year due to genetic and environmental factors— the use of ears. Gonadorelin is a safe and inexpensive way to use in these situations, making it an attractive way to reduce the burden of cancer. Studies show that ten years of use of gonadorelin can reduce the risk of breast cancer by up to 50%, and 15 years of use of gonadorelin can reduce the risk by 70%.
However, the benefits of gonadorelin go beyond breast cancer prevention. However, studies have shown that adjuvant anti-estrogen therapy reduces disease progression by 50% if the cancer is estrogen-sensitive. Unfortunately, treatment is currently available Cancer cells tend to develop resistance to them over time, so their effectiveness is limited. This resistance usually results from increased expression of estrogen receptors, which is the cause. It is impossible to block all estrogen receptors without serious side effects. Gonadorelin may avoid this problem primarily by reducing the expression of estrogen. It directly reduces the growth of estrogen-sensitive cancers and increases receptor efficacy, Blocks the substance, and prolongs its lifespan.
Studies of postmenopausal women with hyperandrogenism (too much estrogen) have shown that long-term GnRH treatment lowers total estrogen levels and reduces the risk of developing breast cancer. This occurs without serious side effects and therefore provides an alternative to previous treatments, surgical removal of the ovaries.

Gonadorelin – a Breakthrough in Prostate Cancer
The use of GnRH in men with prostate cancer began in 1979 and was known as medical castration. However, this treatment eventually led to interesting discoveries. Some androgens are formed locally in the prostate through a mechanism called endocrinology. Of course, this means that GnRH blockade is only partially effective in treating prostate cancer. With the help of Gonadorerin, scientists have developed two new medications approved by the FDA for the treatment of castration-resistant prostate cancer (CRPC).
These substances are very important and provide a new line of defense against the progression and metastasis of prostate cancer. They can also be used prophylactically in older men. The use of gonadorelin and new topical medications in treating prostate cancer is known as complex androgen deprivation (CAB). CAB, which combines effective screening and early detection, is one of the few treatments in oncology that offers treatment and remission. CAB can cure 99% of all prostate cancers when used effectively and with early detection.

Gonadorelin May Reduce Dementia Risk
Studies show that sex hormones, especially luteinizing hormone (LH), act on the brain in ways beyond the realm of sexual dimorphism and fertility. Indeed, increased menopausal-related LH correlates with an increased incidence of Alzheimer’s disease and reduced memory capacity in
humans and animals. Rats treated with LH exhibit poor memory and hippocampal dysfunction. This is a defect that is remedied by the administration of LH blockers.
Further research on LH shows that higher hormone levels are associated with increased neuropathology. In particular, LH has been shown to promote the formation of plaques associated with Alzheimer’s disease. Therefore, it is clear that lowering LH levels will help slow the progression of Alzheimer’s disease.
After all, testosterone is beneficial to brain health and helps maintain cognitive function. Therefore, blocking the entire hypothalamus-pituitary-gondola axis is not always effective for treating Alzheimer’s disease. For this reason, scientists have sought to test gonadorelin derivatives to see if selective disruption of LH production is possible and has potential benefits. This ongoing study says that leuprolide, a common substance used to treat uterine fibroids and GnRH receptor agonists, effectively reduces the risk of Alzheimer’s disease compared to other gonadotropin analogs. It led to understanding. In this situation, leuprolide can be used to offset the risk of CAB for Alzheimer’s disease. In particular, the ability of leuprolide to downregulate serum gonadotropin levels (especially LH) is generally sufficient to offset the effects of decreased testosterone.
Researchers are currently working to understand how the genetic interactions of Alzheimer’s disease can be disrupted to treat and prevent Alzheimer’s disease. Gonadorelin is an important peptide in this study.

Gonadorelin & Future Research

Gonadorelin is not a new peptide in treating human and mammalian diseases. Still, researchers are constantly discovering new ways in which GnRH and GnRH analogs act in normal physiology and disease development. The discovery that gonadorelin may play a role in treating prostate cancer is a breakthrough that has allowed physicians to develop highly effective treatments. When prostate cancer develops, 99% of people can be completely cured. Gonadorelin exhibits minimal side effects and low oral and excellent subcutaneous bioavailability in mice.

All orders ship same day if placed by 2pm PST.  Peptides synthesized and lyophilized in the USA.
This product is strictly for research/laboratory use only.  Human or animal use and/or consumption is strictly prohibited by law.  Only qualified and licensed professionals should handle these products.  Any information found on Biotech Peptides is strictly for educational purposes only.  Refer to our terms and conditions for more details.

Additional information

Brand

Biotech Peptides

22 reviews for Gonadorelin (GnRH) (10mg)

  1. Mariana Wopat

    I have recommended this to all my colleagues! thumbs up

  2. Sunil Ghuptkur

    Biotech comes highly recommended. Even when I experienced problems with emails not arriving in my Hotmail account, customer care was fast to reply. They assured me that the money had been received and that the package would arrive the following day.

  3. Chee Nguyen

    Like that there’s a lot of information about each peptide. Very educational and helpful when picking out products.

  4. Robert Lesner

    Thanks for offering different payment options and the next business day delivery guarantee. My card kept getting declined so I paid through the Paypal link Taylor from customer service emailed me. Much appreciated.

  5. Brian S. Brian S. Casselberry

    There was this one time one of the bottles came a bit cracked. There was no liquid spill at all and everything was fine, but I was still a bit skeptic so I called CS and they told me the bottle is fine, but they’re still gona sent another one, because safety first and why risk it. I loved that and made me really trust them.

  6. Gerald Nila Jr

    ¡Increíble compañía! recomendé a todos

  7. Lisa Berglund

    They came highly recommended by a friend and after shopping with them i see why!

  8. Brian Lewis

    My company has done business with them for a very long time now and we are very pleased and intend to continue choosing Biotech for our peptide needs

  9. Brett Denver

    Everything, from beginning to end, is absolutely flawless

  10. Aleksey Chernyakhovsky

    Had to wait a few days until this product was back in stock but once they got it they sent it over asap. Happy with the service.

  11. Jon Lewis

    Really good products

  12. Austin Bishop

    First found out about Biotech a few months ago, explored their site but wasn’t interested in purchasing at the time. Now had a need for a few peptides with a new project and decided to revsisit and see what they had in stock. Luckily had whatever I needed. Process was basic and easy, not much to it. Everything came in about a span of 24 hours. Pepetides check out and i’ll probbaly purchase from them again.

  13. Stephen Webb

    I love BP’s packaging quality. I know packaging and stuff like this is not that big of a deal compared to the quality of the products, but I’ve gotten vials from other companies where the label was falling off the glass. Not tryna be rude or something but how are you gonna trust the quality of a peptide when the quality of the packaging glue is questionable? Just a thought

  14. Brayden G.

    Standard process of payment and product retrival. Products check out in in regards to purity.

  15. Mike Knowls

    Like how they package everything safely!

  16. Todd Web

    I have noticed they run out of products quick. I also noticed they restock just as fast.

  17. Marcus Downey

    They stock up pretty quickly! I had to place an order last week but they were out of the peptide I needed. Noticed they restocked on a lot of products a few days later.

  18. Janet Heughs

    Their peptides are top teir quality. Their employees are as good as the products they sell. My only comment again is I wish they were a smidge quicker on restocks.

  19. Amy Larson

    Can’t say enough good things about this company. Consistent with their products and great work ethic with their employees.

  20. Reg Sneed Jr.

    Storage life on these are outstanding.

  21. Danny scott

    Biotech Peptides has got to be in my top 3 peptide suppliers. They get my peptides in safe and on time. Peptides are of good quality as well!

  22. Deniz Burduroglu

    Got a 10% off code after my first purchase which was nice.

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