Lipopeptide (Biopeptide EL) (Topical) (200mg)

$220.00

Lipopeptide (Topical) peptides are Synthesized and Lyophilized in the USA.

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SKU: Lipopeptide-Biopeptide-EL-Topical-200mg Category:

Description

Lipopeptide (Biopeptide EL) Peptide

Lipopeptide (topical) is a compound made up of a lipid and a peptide. TLR 1 and other Toll-like receptors appear to bind to this peptide. It has been researched within skin cells to measure its potential impact on the production of vital proteins to the skin’s extracellular matrix (ECM). The most important proteins are considered to be collagen, elastin, and hyaluronic acid. According to scientific research, Lipopeptide may potentially enhance the creation and growth of collagen and hyaluronic acid within the ECM.[1]

It has also been closely studied within the context of collagen synthesis, and the production of hyaluronic acid. It appears to collaborate with cell membranes to strengthen and rejuvenate natural cell processes, rebuilding them to maximize their functional potential. Lipopeptide appears to be more biocompatible with the skin’s natural structure than other water-soluble peptides. Lipopeptide is formed as a metabolic product by microorganisms such as bacteria and fungi and may host antibiotic, antifungal, and anticancer characteristics.

Specifications

Sequence: Pal-Val-Gly-Val-Ala-Pro-Gly-OH or Palmitoyl – Hexapeptide-12

Molecular Formula: C38H68N6O8

Molecular Weight: 736.98g/mol

Synonyms: Oligopeptide-34, Biopeptide EL

Lipopeptide Research

Lipopeptide has been suggested to act primarily to support endogenous collagen and hyaluronic acid synthesis.[2] Lipopeptide research is restricted. Nonetheless, general characteristics have been hypothesized in research that has been conducted.

Lipopeptide and Skin Cells
Collagen is a vital component of the extracellular matrix. It acts to support the skin barrier, and is considered to naturally taper in production with time. Research studies in Lipopeptide exposure suggest that the peptide may support an overall reduction of skin cell aging, and maintain endogenous protein production. Exposure to Lipopeptide, according to researchers, may potentially improve elasticity and hydration through the maintenance of collagen synthesis. It may also promote the production of other proteins that support skin structure, including fibrillin and elastin.[3] Scientists report that the peptide was also apparently “chemotactic for fibroblasts and monocytes, with optimal activity at approximately 10(-8) M.”

Lipopeptide and Muscle Mass
Research indicates that so called “collagen peptides,” of which Lipopeptide is classified, may possibly support the development and proliferation of muscle cells, even in research models of Sarcopenia (age-related musclular decline) and Duchenne Muscle Dystrophy (DMD). Lipopeptide may possibly improve the synthesis of muscle proteins such as creatine while stimulating muscle cell proliferation after extreme physical exertion.

Lipopeptide and Heart Conditions
Research has suggested that Lipopeptide may potentially have the downstream impact of mitigating cardiac dysfunction. Collagen is a vital ancillary in providing structure for arteries—blood vessels that carry blood from the heart outwards. Collagen deficiency may cause blood vessels to reduce in flexibility and elasticity, which may result in atherosclerosis. In such a condition, Lipopeptide may work to intervene in this process, through the production and synthesis of collagen.

Other General Research in Lipopeptide
Gastrointestinal Tract: According to research, the peptide’s potential capacity to increase collagen synthesis may thereby hinder intestinal permeability, possibly mitigating cases of leaky gut syndrome.
Infections: Lipopeptide may potentially mitigate the onset of certain tissue infections caused by gram-positive bacteria. It may also impact infections caused by multidrug-resistant bacteria (Staphylococcus aureus, Streptococcus pyogenes, and Enterococcus faecalis), or right-sided infective endocarditis (a bacterial infection of the heart lining, and blood vessels). Research studies are ongoing.
Bacteremia: Similarly to the above, concentrated research has suggested that Lipopeptide may reduce instances of Bacteremia (a bacterial infection in the bloodstream).
Agricultural Preservation: Lipopeptide may exhibit antimicrobial characteristics, which may be helpful within agricultural contexts.

Disclaimer: The products mentioned are not intended for human or animal consumption. Research chemicals are intended solely for laboratory experimentation and/or in-vitro testing. Bodily introduction of any sort is strictly prohibited by law. All purchases are limited to licensed researchers and/or qualified professionals. All information shared in this article is for educational purposes only.

 

References

  1. Al-Atif H. Collagen Supplements for Aging and Wrinkles: A Paradigm Shift in the Fields of Dermatology and Cosmetics. Dermatol Pract Concept. 2022 Jan 1;12(1):e2022018. doi: 10.5826/dpc.1201a18. PMID: 35223163; PMCID: PMC8824545.
  2. Floquet N, Héry-Huynh S, Dauchez M, Derreumaux P, Tamburro AM, Alix AJ. Structural characterization of VGVAPG, an elastin-derived peptide. Biopolymers. 2004;76(3):266-80. doi: 10.1002/bip.20029. PMID: 15148686.
  3. Senior RM, Griffin GL, Mecham RP, Wrenn DS, Prasad KU, Urry DW. Val-Gly-Val-Ala-Pro-Gly, a repeating peptide in elastin, is chemotactic for fibroblasts and monocytes. J Cell Biol. 1984 Sep;99(3):870-4. doi: 10.1083/jcb.99.3.870. PMID: 6547961; PMCID: PMC2113419.
  4. Schagen, Silke Karin. “Topical peptide treatments with effective anti-aging results.” Cosmetics 4.2 (2017): 16.
  5. Johnson Jr, Wilbur, et al. “Safety assessment of tripeptide-1, hexapeptide-12, their metal salts and fatty acyl derivatives, and palmitoyl tetrapeptide-7 as used in cosmetics.” International journal of toxicology 37.3_suppl (2018): 90S-102S.
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This product is strictly for research/laboratory use only.  Human or animal use and/or consumption is strictly prohibited by law.  Only qualified and licensed professionals should handle these products.  Any information found on Biotech Peptides is strictly for educational purposes only.  Refer to our terms and conditions for more details.

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