Lipopeptide (Biopeptide EL) (Topical) (200mg)


Lipopeptide (Topical) peptides are Synthesized and Lyophilized in the USA.

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What is the Lipopeptide (Biopeptide EL) peptide?

Lipopeptide (topical) is a compound made up of a lipid and a peptide. TLR 1 and other Toll-like receptors appear to bind to this collagen peptide. The largest organ of the human body is the skin, which contains various cells, proteins, and structures. The most important proteins are collagen, elastin, and hyaluronic acid. According to scientific research, Lipopeptide may enhance the creation and growth of collagen and hyaluronic acid within the skin.[1] Researchers reported that “71% of the women in the intervention group experienced anti-wrinkle effects. Dermal density improved by 11% after 1 week.” It may also increase the synthesis of natural collagen and the productivity of HA. It appears to collaborate with cell membranes to strengthen and rejuvenate natural cell processes, rebuilding them to maximize their growth potential. As a result, this peptide is widely regarded by researchers as one of nature’s most potent anti-aging agents. Lipopeptide appears to be more biocompatible with the skin’s natural structure than other water-soluble peptides. Lipopeptide is formed as a metabolic product by microorganisms such as bacteria and fungi and may host antibiotic, antifungal, and anticancer properties.


Sequence: Pal-Val-Gly-Val-Ala-Pro-Gly-OH or Palmitoyl – Hexapeptide-12

Molecular Formula: C38H68N6O8

Molecular Weight: 736.98g/mol

PubChem: CID 71435492

Synonyms: Oligopeptide-34, Biopeptide EL

Reconstitution: Required


Lipopeptide, akin to other collagen peptides, appears to work primarily to boost collagen and hyaluronic acid synthesis.[2] It may be a more powerful collagen peptide due to its apparent strong biocompatibility with the skin’s natural structure. Lipopeptide research is restricted. Nonetheless, beneficial properties have been highlighted in research that has been conducted. These properties are apparently evident in all places of the body where collagen and hyaluronic activities are required.

Lipopeptide and Skin Health
Collagen is a vital component of the skin. It works to strengthen the skin while also increasing its suppleness and moisture. With age, collagen production and efficacy drop, resulting in dry skin and the development of facial lines and wrinkles. Research studies in Lipopeptide administration suggest that it may help reduce and prevent the prevalence of skin aging by decreasing wrinkles and skin dryness. The application of Lipopeptide, according to researchers, may improve skin elasticity and hydration by increasing collagen synthesis. It may also promote the production of proteins that help improve the skin structure, including fibrillin and elastin.[3] Scientists report that the peptide was also apparently “chemotactic for fibroblasts and monocytes, with optimal activity at approximately 10(-8) M.”

Lipopeptide and Muscle Mass
Collagen is a protein that is plentiful in the body and thus an essential component of skeletal muscle. Research shows that collagen peptides, such as the Lipopeptides, may help enhance muscle mass in people with Sarcopenia (the loss of muscle that occurs with age) and Duchenne Muscle Dystrophy (DMD). Lipopeptide may improve the synthesis of muscle proteins such as creatine while stimulating muscle mass after an exercise. Research is still ongoing to further determine the ability of Lipopeptide to improve muscle mass.

Lipopeptide and Heart Conditions
Research has suggested that Lipopeptide may also help reduce the risk of heart diseases. Collagen is a vital ancillary in providing structure for arteries—blood vessels that carry blood from the heart to all parts of the body. Collagen deficiency will cause blood vessels to lose their flexibility and elasticity, which may result in atherosclerosis. In such a condition, Lipopeptide may work to intervene in this process, boosting the production and synthesis of collagen.

Other General Research in Lipopeptide
Gastrointestinal Tract: According to research, Lipopeptide, with its potential capacity to increase collagen synthesis, may be a potent adjunct in the treatment of leaky gut syndrome, also known as intestinal permeability.
Infections: Lipopeptide may be used to treat skin and tissue infections caused by gram-positive bacteria. It has the potential to help treat infections caused by multidrug-resistant bacteria (Staphylococcus aureus, Streptococcus pyogenes, and Enterococcus faecalis). It may also treat right-sided infective endocarditis (a bacterial infection of the heart lining, and blood vessels).
Bacteremia: Similarly to the above, more concentrated research has suggested that Lipopeptide may help treat Bacteremia (a bacterial infection in the bloodstream, characterized by fever, rapid heart rate, chills, confusion, and low blood pressure).
Skin, Nail, Hair Care: Lipopeptide may be used as an additive in the production of cosmetics targeted at skin care, due to its potential anti-aging properties.[4]  It may also aid the growth of hair and nails via its apparent collagen-enhancing ability. Lipopeptide may also act as a potent antimicrobial agent which may be helpful in the preservation of crop and dairy products
Agricultural Preservation: Lipopeptide may also act as a potent antimicrobial agent which may be helpful in the preservation of crop and dairy products.


A lipid attached to a peptide is a molecule known as Lipopeptide. It is a collagen peptide and has been researched for its potential to binds to TLR 1 and other Toll-like receptors. It appears to function to boost the synthesis of collagen and hyaluronic acid. Lipopeptide has been suggested by scientists to be highly biocompatible with the natural structure of the skin than other water-soluble peptides. However, Lipopeptide is only available for educational and scientific purposes by licensed researchers and is not intended for human use.


  1. Al-Atif H. Collagen Supplements for Aging and Wrinkles: A Paradigm Shift in the Fields of Dermatology and Cosmetics. Dermatol Pract Concept. 2022 Jan 1;12(1):e2022018. doi: 10.5826/dpc.1201a18. PMID: 35223163; PMCID: PMC8824545.
  2. Floquet N, Héry-Huynh S, Dauchez M, Derreumaux P, Tamburro AM, Alix AJ. Structural characterization of VGVAPG, an elastin-derived peptide. Biopolymers. 2004;76(3):266-80. doi: 10.1002/bip.20029. PMID: 15148686.
  3. Senior RM, Griffin GL, Mecham RP, Wrenn DS, Prasad KU, Urry DW. Val-Gly-Val-Ala-Pro-Gly, a repeating peptide in elastin, is chemotactic for fibroblasts and monocytes. J Cell Biol. 1984 Sep;99(3):870-4. doi: 10.1083/jcb.99.3.870. PMID: 6547961; PMCID: PMC2113419.
  4. Schagen, Silke Karin. “Topical peptide treatments with effective anti-aging results.” Cosmetics 4.2 (2017): 16.
  5. Johnson Jr, Wilbur, et al. “Safety assessment of tripeptide-1, hexapeptide-12, their metal salts and fatty acyl derivatives, and palmitoyl tetrapeptide-7 as used in cosmetics.” International journal of toxicology 37.3_suppl (2018): 90S-102S.
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This product is strictly for research/laboratory use only.  Human or animal use and/or consumption is strictly prohibited by law.  Only qualified and licensed professionals should handle these products.  Any information found on Biotech Peptides is strictly for educational purposes only.  Refer to our terms and conditions for more details.

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