Matrixyl (Topical) (200mg)

(26 customer reviews)

$190.00

Matrixyl (topical) peptides are Synthesized and Lyophilized in the USA.

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Quantity5 - 910 +
Discount5%10%
Price$180.50$171.00
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(Required for reconstitution)
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SKU: Matrixyl-200mg Category:

Description

What is the Matrixyl peptide?

Matrixyl is a lipopeptide, combining fatty acids with amino acids. It is also considered a synthetic isomer (an isomer is a molecule with an identical structure to another molecule but different atomic components). The active element in Matrixyl is a second peptide known as Micro-collagen.[1] Researchers report that “The conjugation with the palmitoyl moiety results in more effective delivery across the skin and better stability to skin proteases.”

Specifications

AKA: palmitoyl pentapeptide-3

MOLECULAR FORMULA: C39H75N7O10

MOLECULAR WEIGHT: 802.05 g/mol

SEQUENCE: Pal-Lys-Thr-Thr-Ser-OH or Pal-KTTS-OH

PUBCHEM: CID 9897237

RECONSTITUTION: Required

Matryxil Action

Matrixyl appears to combine two matrikines, namely palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7. It is a small molecule that is highly porous in the skin. Structurally, it is similar to collagen precursors. Most of the effects of Matrixyl application appear to be mediated in the skin’s dermis. It may promote the process of self-healing in the lower layers of the skin, and has been termed an anti-wrinkle peptide. It appears to participate in the neosynthesis of extracellular matrix macromolecules.[2] For example, the researchers note that “Delicate balance between the wound healing properties and pro-fibrotic abilities of pentapeptide should be considered for selecting therapeutic dose for scar prevention.” In the presence of Matrixyl, the dermal layers may begin to heal themselves, accelerating the healing and closure of wounds. Cells known as fibroblasts are responsible for knitting together wounds of the skin. As popularly known, wounds take longer to heal with age progression. One of the reasons for this occurrence is that fibroblasts gradually lose their capacity for collagen production. Matrixyl is the trademark name for palmitoyl pentapeptide-3, a potentially powerful peptide molecule found in the latest generation of high-end anti-wrinkle skin care products. Matryxil may become even more effective when combined with other peptides.

What Does Matrixyl Do?

Matrixyl was discovered through two independent streams of dermatological research: the search for substances that accelerate healing skin wounds and the exploration of the causes of wrinkles.[3] Matrixyl appears to act as a signaling molecule that stimulates collagen and elastin production. Similar to copper peptides, Matrixyl may stimulate the lower layers of the skin to heal themselves, accelerating the healing of wounds. Cells called fibroblasts are responsible for knitting together wounds of the skin. Matrixyl appears to stimulate the “matrix” layers in the skin – primarily collagen and fibronectin. The aging process is mainly divided into intrinsic and extrinsic types. Intrinsic aging occurs via a degenerative process characterized by the loss of collagen. This process results in wrinkling and thinning of the skin and loss of elasticity, and increased stiffness. Matrixyl may help to counteract this natural part of the aging process by signaling the extracellular matrix to produce elastin and collagen. These are the two ground substances that contribute to the elasticity and smoothness of the skin. In doing so, Matrixyl may play an anti-wrinkling role for the skin. When used in combination with other peptides, studies have suggested the peptide’s ability to improve the skin’s health tremendously.

Matrixyl (Palmitoyl Pentapeptide-3) Research

Clinical research has observed that Matrixyl may exhibit the following effects:
– Enhance overall collagen synthesis by up to 117%
– Improve collagen IV synthesis by up to 327%
– Increase hyaluronic acid synthesis by up to 267%
Deep wrinkles may undergo reduction by 50%. More minor wrinkles and fine lines have been observed sometimes to fade entirely away. In addition, every participant in one particular research study exhibited noticeable improvement within two weeks.[4] The result was fewer wrinkles and younger-looking skin. The results are reported to be even more prominent when combined with other peptides (as in the Replexion formulation). A study conducted to compare the benefits of Matrixyl with Retinol (an anti-wrinkle product) observed that Matrixyl appeared to be a more effective anti-wrinkle product.[5] This result is attributed to the hypothesis that Matrixyl use is devoid of the side effects related to Retinol use.

Conclusion

As of today, the peptide is approved for in-vitro studies only. In-vitro studies are performed outside of the body, such as through cell cultures. These products are not medicines and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment, or disease.

References

  1. Errante F, Ledwoń P, Latajka R, Rovero P, Papini AM. Cosmeceutical Peptides in the Framework of Sustainable Wellness Economy. Front Chem. 2020 Oct 30;8:572923. doi: 10.3389/fchem.2020.572923. PMID: 33195061; PMCID: PMC7662462.
  2. Park H, An E, Cho Lee AR. Effect of Palmitoyl-Pentapeptide (Pal-KTTKS) on Wound Contractile Process in Relation with Connective Tissue Growth Factor and α-Smooth Muscle Actin Expression. Tissue Eng Regen Med. 2017 Jan 19;14(1):73-80. doi: 10.1007/s13770-016-0017-y. PMID: 30603464; PMCID: PMC6171572.
  3. Robinson LR, Fitzgerald NC, Doughty DG, Dawes NC, Berge CA, Bissett DL. Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin. Int J Cosmet Sci. 2005 Jun;27(3):155-60. doi: 10.1111/j.1467-2494.2005.00261.x. PMID: 18492182.
  4. Tałałaj U, Uścinowicz P, Bruzgo I, Surażyński A, Zaręba I, Markowska A. The Effects of a Novel Series of KTTKS Analogues on Cytotoxicity and Proteolytic Activity. Molecules. 2019 Oct 15;24(20):3698. doi: 10.3390/molecules24203698. PMID: 31618846; PMCID: PMC6832239.
  5. Park H, An E, Cho Lee AR. Effect of Palmitoyl-Pentapeptide (Pal-KTTKS) on Wound Contractile Process in Relation with Connective Tissue Growth Factor and α-Smooth Muscle Actin Expression. Tissue Eng Regen Med. 2017 Jan 19;14(1):73-80. doi: 10.1007/s13770-016-0017-y. PMID: 30603464; PMCID: PMC6171572.
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Additional information

Brand

Biotech Peptides

26 reviews for Matrixyl (Topical) (200mg)

  1. Taylor Gardner

    I ordered several products from Biotech Peptides, GHK-Cu, BPC157, TB500, and CJC Ipamorelin blend. Products came quickly and were well packaged. Overall very pleased to find a reputable company and will order again. Definitely recommended.

  2. Diane Havranek

    The old saying you get what you pay for applies here. Yes, there’s cheaper sources. I’d rather not take the chance personally.

  3. Dale Gardner

    You guys have such a wide range of peptides you just cannot find anywhere else. Amazing

  4. Jasper Hall

    I really like this company. Been a repeat customer for months now. Have only had one incident where my package was lost in the craze of the holidays. They resent the package free of charge.

  5. Rory Dean

    I am very happy with my order

  6. Nathan Emond

    Amazing to see some topical peptides. Wish they would bring in more types/options though however!

  7. Chad Splindler

    I had an issue with money processing and when I called them, they weren’t available, but they reached out to me as soon as they noticed, even though they didn’t know I reached out to them first. This is the type of stuff that makes you trust a company

  8. Justing Pishkar

    I started buying out of curiosity about a new company out in the market, I am happy to report they have won me over as a customer.

  9. Taylor Ward

    You definitely get what you paid for when you order from here. Id never take the chance to order from somewhere else again.

  10. Chelsea Gamba

    Biotech Peptides is the go to supplier. Great return time on emails. Peptides shipped out quickly as well.

  11. Jo Grimm

    Fantastic service, Taylor is very helpful when it comes to fixing technical issues.

  12. Brandon Assad

    Thank you for giving me a 10% discount on my next order after my 10th purchase.

  13. aria fields

    I would recommend them.

  14. evan walker

    Did I just stumble upon the Holy Grail of Peptide Companies? I think I did

  15. brett wallen

    Biotech peptides is the best place to purchase peptides.

  16. james silver

    After placing an order yesterday, my package arrived this morning. There were no issues with the turnaround time and the staff was very helpful and friendly.

  17. Gabe Habib

    I couldn’t find out how to alter the address on my account because I couldn’t figure out how to do it. Taylor was a godsend, and they were able to address the problem immediately. It just took a few minutes for someone to pick up the phone and provide assistance.

  18. Ellen swarts

    After a colleague suggested this to me, I’ve never looked for a new source of supplies again.

  19. Anthony Roxan

    Their team is always readily available to fix any issues or look at any of my concerns.

  20. Chris Trillo

    This is one if the best topical peptides on the market overall and BP makes it so pure it is crazy how fast you see results in research.

  21. Will Blumrick

    My package came in perfect condition and peptides looked great!

  22. Kenny Ibrahim

    This company has the fastest shipping I have ever experienced.

  23. Joe Vitug

    The purity is unmatched. Best quality I have found in the past few years.

  24. Duncan Clark

    I find their blog section very informative and reliable. Any time you lack knowledge about a certain substance, you can just go to their blog and they have some articles that can explain the peptide and what it helps with or research it has been in.

  25. Damien Darkoski

    This is my first time ordering, hopefully everything will go smoothly. Have heard a lot of good things about the peptides and company from my fellow researchers.

  26. Zander White

    The best topical peptide out there hands down. This is the place to buy the highest quality Matrixyl

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