What Is Matrixyl Peptide?
Matrixyl is a lipopeptide wherein it combines fatty acid mixed with amino acids. It is also considered a synthetic isomer (an isomer is a molecule with an identical structure to another molecule but different atomic components). The active element in Matrixyl is a second peptide known as Micro-collagen.
AKA: palmitoyl pentapeptide-3
MOLECULAR FORMULA: C39H75N7O10
MOLECULAR WEIGHT: 802.05 g/mol
SEQUENCE: Pal-Lys-Thr-Thr-Ser-OH or Pal-KTTS-OH
PUBCHEM: CID 9897237
Matrixyl combines two matrikines, namely palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7. It is a small molecule that is highly porous in the skin. Structurally, it is similar to collagen precursors. Most of the effects of matrixyl application are mediated in the skin’s dermis. It promotes the process of self-healing in the lower layers of the skin. It has also been termed an anti-wrinkle peptide.
It participates in the neosynthesis of extracellular matrix macromolecules. In the presence of Matrixyl, the dermal layers begin to heal themselves, thereby accelerating the healing and closure of wounds. Cells known as fibroblasts are responsible for knitting together wounds of the skin. As popularly known, wounds take longer to heal with age progression.
One of the reasons for this occurrence is that fibroblasts gradually lose their capacity for collagen production. Matrixyl is the trademark name for palmitoyl pentapeptide-3, a powerful and significant peptide molecule found in the latest generation of high-end anti-wrinkle skin care products. Matryxil becomes even more effective when combined with other peptides.
What Does Matrixyl Do?
Matrixyl was discovered through two independent streams of dermatological research: the search for substances that accelerate healing skin wounds and the exploration of the causes of wrinkles. Matrixyl acts as a signaling molecule that stimulates collagen and elastin production. Similar to copper peptides, Matrixyl stimulates the lower layers of the skin to heal themselves, thus accelerating the healing of wounds. Cells called fibroblasts are responsible for knitting together wounds of the skin.
Matrixyl stimulates the “matrix” layers in the skin – primarily collagen and fibronectin. The aging process is mainly divided into intrinsic and extrinsic types. Intrinsic aging occurs via a degenerative process characterized by the loss of collagen. This process results in wrinkling and thinning of the skin and loss of elasticity, and increased stiffness.
Matrixyl helps to counteract this natural part of the aging process. It does this by signaling the extracellular matrix to produce elastin and collagen. These are the two ground substances that contribute to the elasticity and smoothness of the skin. In doing so, matrixyl plays an anti-wrinkle role for the skin. When used in combination with other peptides, it has improved the skin’s health tremendously.
Is Matrixyl (palmitoyl pentapeptide-3) An Effective Anti-wrinkle Product?
Clinical research has proven that Matrixyl has the following effects:
– Enhance overall collagen synthesis by up to 117%
– Improve collagen IV synthesis by up to 327%
– Increase hyaluronic acid synthesis by up to 267%
Deep wrinkles get reduced by half. More minor wrinkles and fine lines have been observed sometimes to fade entirely away. In addition, every participant in the study showed noticeable improvement within two weeks. The result was fewer wrinkles and younger-looking skin.
Very few ingredients show more promise and greater effectiveness than Matrixyl. The results are even more beneficial when combined with other peptides (as in the Replexion formulation). A study conducted to compare the benefits of matrixyl with retinol (another commonly-used anti-wrinkle product) declared that matrixyl was a more effective anti-wrinkle product. This result is attributed to the fact that matrixyl use is devoid of any side effects of retinol use.
As of today, the peptide is approved for in-vitro studies only. In-vitro studies are performed outside of the body, such as through cell cultures. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment, or disease. Bodily introducing any kind to humans or animals is strictly forbidden by law.