Matrixyl (200mg)

(26 customer reviews)


Matrixyl peptides are Synthesized and Lyophilized in the USA.

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Quantity 5 - 910 +
Discount 5%10%
Price $180.50$171.00
Orders over $200 receive:
FREE - 30ml bottle of bacteriostatic water
(Required for reconstitution)
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SKU: Matrixyl-200mg Category:


Matrixyl Peptide

Matrixyl is a lipopeptide, combining fatty acids with amino acids. It is also considered a synthetic isomer (an isomer is a molecule with an identical structure to another molecule but different atomic components). The active element in Matrixyl is a second peptide known as Micro-collagen.[1] Researchers report that “The conjugation with the palmitoyl moiety [may] result in more effective delivery across the skin and better stability to skin proteases.”


OTHER KNOWN TITLES: palmitoyl pentapeptide-3


MOLECULAR WEIGHT: 802.05 g/mol

SEQUENCE: Pal-Lys-Thr-Thr-Ser-OH or Pal-KTTS-OH

Matrixyl Research

Matrixyl appears to combine two matrikines, namely palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7. It is a small molecule that is considered to be highly porous in the skin. Structurally, it is similar to collagen precursors. Researchers suggest that the peptide may act to promote the process of repair in the lower layers of damaged skin cell tissues, and has also been termed an “anti-wrinkle” peptide due to the apparent impact it has on wrinkle depth and crease development. It appears to participate in the neosynthesis of extracellular matrix macromolecules.[2] For example, the researchers note that “Delicate balance between the wound healing properties and pro-fibrotic abilities of pentapeptide should be considered for … scar prevention.” In the presence of Matrixyl, the dermal layers may begin to heal themselves, possibly resulting in an acceleration of the natural processes of healing and closure of wounds via cells known as fibroblasts. Fibroblasts appear to gradually lose their capacity for collagen production over time.

Matrixyl was discovered through two independent streams of dermatological research: the search for substances that accelerate repair in damaged skin cells and the exploration of the causes of wrinkle development.[3] Matrixyl appears to act as a signaling molecule that may potentially stimulate collagen and elastin production. Similar to copper peptides, Matrixyl has been suggested to stimulate the lower layers of skin cells to repair damaged tissues in an accelerated manner.  Matrixyl appears to stimulate the “matrix” layers in the epidermis – primarily collagen and fibronectin. Cell aging has been divided by researchers into intrinsic and extrinsic types. Intrinsic cell aging occurs via a degenerative process characterized by the loss of collagen. This process results in wrinkling and thinning of the skin and loss of elasticity, and increased stiffness. Matrixyl may signal the extracellular matrix to produce elastin and collagen, potentially combatting cell aging phenomenon.

Researchers have suggested that in the course of study findings, that Matrixyl may potentially induce collagen synthesis by up to 117% over control levels, collagen IV synthesis by up to 327%, and hyaluronic acid synthesis by up to 267%. [4] The researchers also noted that certain synergistic compounds may have contributed to an increase in these finding results.[5]

Disclaimer: The products mentioned are not intended for human or animal consumption. Research chemicals are intended solely for laboratory experimentation and/or in-vitro testing. Bodily introduction of any sort is strictly prohibited by law. All purchases are limited to licensed researchers and/or qualified professionals. All information shared in this article is for educational purposes only.



  1. Errante F, Ledwoń P, Latajka R, Rovero P, Papini AM. Cosmeceutical Peptides in the Framework of Sustainable Wellness Economy. Front Chem. 2020 Oct 30;8:572923. doi: 10.3389/fchem.2020.572923. PMID: 33195061; PMCID: PMC7662462.
  2. Park H, An E, Cho Lee AR. Effect of Palmitoyl-Pentapeptide (Pal-KTTKS) on Wound Contractile Process in Relation with Connective Tissue Growth Factor and α-Smooth Muscle Actin Expression. Tissue Eng Regen Med. 2017 Jan 19;14(1):73-80. doi: 10.1007/s13770-016-0017-y. PMID: 30603464; PMCID: PMC6171572.
  3. Robinson LR, Fitzgerald NC, Doughty DG, Dawes NC, Berge CA, Bissett DL. Palmitoyl pentapeptide provides improvement in photoaged human facial skin. Int J Cosmet Sci. 2005 Jun;27(3):155-60. doi: 10.1111/j.1467-2494.2005.00261.x. PMID: 18492182.
  4. Tałałaj U, Uścinowicz P, Bruzgo I, Surażyński A, Zaręba I, Markowska A. The Effects of a Novel Series of KTTKS Analogues on Cytotoxicity and Proteolytic Activity. Molecules. 2019 Oct 15;24(20):3698. doi: 10.3390/molecules24203698. PMID: 31618846; PMCID: PMC6832239.
  5. Park H, An E, Cho Lee AR. Effect of Palmitoyl-Pentapeptide (Pal-KTTKS) on Wound Contractile Process in Relation with Connective Tissue Growth Factor and α-Smooth Muscle Actin Expression. Tissue Eng Regen Med. 2017 Jan 19;14(1):73-80. doi: 10.1007/s13770-016-0017-y. PMID: 30603464; PMCID: PMC6171572.
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This product is strictly for research/laboratory use only.  Human or animal use and/or consumption is strictly prohibited by law.  Only qualified and licensed professionals should handle these products.  Any information found on Biotech Peptides is strictly for educational purposes only.  Refer to our terms and conditions for more details.

Dr. Usman

Dr. Usman (BSc, MBBS, MaRCP) completed his studies in medicine at the Royal College of Physicians, London. He is an avid researcher with more than 30 publications in internationally recognized peer-reviewed journals. Dr. Usman has worked as a researcher and a medical consultant for reputable pharmaceutical companies such as Johnson & Johnson and Sanofi.

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Biotech Peptides

26 reviews for Matrixyl (200mg)

  1. Taylor Gardner

    I ordered several products from Biotech Peptides, GHK-Cu, BPC157, TB500, and CJC Ipamorelin blend. Products came quickly and were well packaged. Overall very pleased to find a reputable company and will order again. Definitely recommended.

  2. Diane Havranek

    The old saying you get what you pay for applies here. Yes, there’s cheaper sources. I’d rather not take the chance personally.

  3. Dale Gardner

    You guys have such a wide range of peptides you just cannot find anywhere else. Amazing

  4. Jasper Hall

    I really like this company. Been a repeat customer for months now. Have only had one incident where my package was lost in the craze of the holidays. They resent the package free of charge.

  5. Rory Dean

    I am very happy with my order

  6. Nathan Emond

    Amazing to see some topical peptides. Wish they would bring in more types/options though however!

  7. Chad Splindler

    I had an issue with money processing and when I called them, they weren’t available, but they reached out to me as soon as they noticed, even though they didn’t know I reached out to them first. This is the type of stuff that makes you trust a company

  8. Justing Pishkar

    I started buying out of curiosity about a new company out in the market, I am happy to report they have won me over as a customer.

  9. Taylor Ward

    You definitely get what you paid for when you order from here. Id never take the chance to order from somewhere else again.

  10. Chelsea Gamba

    Biotech Peptides is the go to supplier. Great return time on emails. Peptides shipped out quickly as well.

  11. Jo Grimm

    Fantastic service, Taylor is very helpful when it comes to fixing technical issues.

  12. Brandon Assad

    Thank you for giving me a 10% discount on my next order after my 10th purchase.

  13. aria fields

    I would recommend them.

  14. evan walker

    Did I just stumble upon the Holy Grail of Peptide Companies? I think I did

  15. brett wallen

    Biotech peptides is the best place to purchase peptides.

  16. james silver

    After placing an order yesterday, my package arrived this morning. There were no issues with the turnaround time and the staff was very helpful and friendly.

  17. Gabe Habib

    I couldn’t find out how to alter the address on my account because I couldn’t figure out how to do it. Taylor was a godsend, and they were able to address the problem immediately. It just took a few minutes for someone to pick up the phone and provide assistance.

  18. Ellen swarts

    After a colleague suggested this to me, I’ve never looked for a new source of supplies again.

  19. Anthony Roxan

    Their team is always readily available to fix any issues or look at any of my concerns.

  20. Chris Trillo

    This is one if the best topical peptides on the market overall and BP makes it so pure it is crazy how fast you see results in research.

  21. Will Blumrick

    My package came in perfect condition and peptides looked great!

  22. Kenny Ibrahim

    This company has the fastest shipping I have ever experienced.

  23. Joe Vitug

    The purity is unmatched. Best quality I have found in the past few years.

  24. Duncan Clark

    I find their blog section very informative and reliable. Any time you lack knowledge about a certain substance, you can just go to their blog and they have some articles that can explain the peptide and what it helps with or research it has been in.

  25. Damien Darkoski

    This is my first time ordering, hopefully everything will go smoothly. Have heard a lot of good things about the peptides and company from my fellow researchers.

  26. Zander White

    The best topical peptide out there hands down. This is the place to buy the highest quality Matrixyl

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