Selank (10mg)

(22 customer reviews)


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What is Selank Peptide?

Selank is a Russian product. It is a small peptide showing nootropic and anxiolytic properties. It is a synthetic analog of naturally occurring Tuftsin, an immunomodulatory peptide regulating T helper cells, IL-6, monoamine neurotransmitters, and brain-derived neurotrophic factor (BDNF). In reality, Selank differs from Tuftsin in additional four amino acids in its chain that enhance metabolic stability and half-life.
It has been tested in clinical trials as a suitable drug for generalized anxiety disorder.
Anxiety Effects Based on Genes Related to GABA Neurotransmitters
Selank Peptide & Immune System in Anxiety
Research about Memory and Learning
Selank Research and Pain


Molecular Formula: C33H57N11O9

Molecular Weight: 751.89 g/mol

Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro

PubChem: CID 11765600

CAS Number: 129954-34-3

Reconstitution: Required

Selank Researches

Anxiety Effects Based on Genes Related to GABA Neurotransmitters
Dr. Anastasiya Volkova of the Institute of Molecular Genetics in Russia has said, “numerous clinical studies have shown that Selank has strong antianxiety and neuroprotective effects in the treatment of anxiety. Selank and classical antianxiety medications such as benzodiazepine have a similar mode of action. Selank allosterically modulates GABAA receptors and increases the inhibitory action of GABA.” The peptide reduces anxiety, improves mood, decreases stress levels, and positively influences memory and learning. Small doses of Selank have a sedating effect like benzodiazepines. However, unlike the latter, it is neither habit-forming nor leads to symptoms of withdrawal or amnesia.
It has been observed to strongly influence expression of seven genes and moderately affect the expression of 45 other targets from a set of about 84 genes known to be involved in GABA signaling. Thus the peptide stimulates gene expression in neurons and influences affinity of GABA receptors for GABA. Synergism between Selank and benzodiazepines and other GABA receptor agonists is mediated through alteration of the receptor affinity.
Research in rats shows that Selank and benzodiazepines, when used alone, have similar effects on anxiety, particularly generalized anxiety disorder. The combined use of the two drugs addresses unpredictable chronic mild stress, despite selank being better equipped to relieve anxiety than benzodiazepines.
The effect of Selank on enkephalin degradation modulates its influence on GABA receptors to a certain extent. Studies have shown enkephalins with shorter blood stability in patients with anxiety and phobic disorders. This is caused by increased enkephalinase activity in their blood which degrades the enkephalins. The peptide also inhibits enkephalinase, stabilizes enkephalins, resets the enzymatic pathway, and thus preserves the natural anxiolytic peptides of the body. Studies in murine models of anxiety also support the view of the above hypothesis.

Selank Peptide & Immune System in Anxiety
Rese Selank inhibits the gene responsible for the production of the inflammatory cytokine IL-6 in patients suffering from depression but not in healthy individuals. Thus it can be useful in patients with anxiety-asthenic disorders, severe anxiety, fatigue, headache, heart palpitations, high blood pressure, nerve pain, and depression.
Compared to standard anxiolytic treatments, like benzodiazepines, only Selank improves asthenic symptoms such as fatigue and pain. This is due to its stabilization of enkephalins and modification of expression of IL-6.
The peptide affects expression of nearly 34 genes in the inflammatory pathway including those affecting chemokines, cytokines, and receptors. It specifically affects Bcl6 expression which promotes, immune development. The above work not only helps to reveal the complex biological effects of the peptide but also improves our understanding of the immune system.
Selank and its truncated versions mediate transient alter gene expression for C3, CAsp1, Il2rf, and Xcr1 in the mouse spleen. Selank can thus alter the balance of the immune system and thereby modulate inflammation.

Research about Memory and Learning
Anxiety and learning/memory show a strong inverse association. Like traditional treatment regimens, the peptide reduces the impact of anxiety on cognitive function. The peptide boosts cognitive power directly.
Selank improves memory traceability and storage in rats. This improvement was independent of the anxiety levels of the rats. The peptide thus boots memory beyond its ability to just reduce stress-related impairment of memory.
Peptide triggers better memory through the hippocampal expression of 36 different genes. The majority of the targets are membrane-associated proteins and regulate ion movement across cell membranes. Thus the ion-dependent processes in learning and memory are enhanced by the molecule. Selank has shown preliminary proof towards helping in easy formation and access of memories.
It helps to rescue memory and cognitive abilities after injury in rats administered with neurotoxins. This happens due to the inhibition of catecholamines in the brain. It can thereby assist in restoring cognitive function after an injury, like during the birth process.

Selank Research and Pain
Enkephalins are natural peptides that reduce the severity of pain by associating with opioid receptors. Their levels are high in the human brain and adrenal glands during the stress response. Selank reduces the levels in the brain, thereby suppressing stress response and its harmful effects on memory, learning, and concentration.
Selank displays minimal side effects, low oral bioavailability, and excellent subcutaneous bioavailability in mice. The dose (per kg) used in mice does not scale to humans.

All orders ship same day if placed by 2pm PST.  Peptides synthesized and lyophilized in the USA.
This product is strictly for research/laboratory use only.  Human or animal use and/or consumption is strictly prohibited by law.  Only qualified and licensed professionals should handle these products.  Any information found on Biotech Peptides is strictly for educational purposes only.  Refer to our terms and conditions for more details.

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Biotech Peptides

22 reviews for Selank (10mg)

  1. Lucas Allen

    I work as an assistant tech in a lab at my local university and my professor and I were very pleased with the results.

  2. Levi Morris

    Such a great selection and very fair prices.

  3. Landon Gibson

    honestly I was a bit skeptical ordering these kinds of products from the internet as I usually get it from a compounding pharmacy but i am thoroguhly impresed.

  4. Theo McLean

    Very easy ordering and checkout process

  5. Li Westenfelt

    I can’t wait for my package to get here. Thank you guys for a smooth process

  6. River Brooks

    Without a question, the top website for peptides in the industry. Service was great! products were the best quality i’ve come by. Would recommend to others!

  7. Levi Morris

    You guys were able to refund my order in full, Thanks for that. They do stand by their word. I had placed an order for Selank and typically they get this all sent out and delivered within a few days of placing the order. This time around I never got an e-mail stating my peptides have been shipped or even preparing to be delivered. A few days went by and I e-mailed them to ask about my missing peptides. Turns out they were out of stock and someone forgot to e-mail me informing me of the issue. They offered a full refund or to send out the order once they get it in but I went with getting my money back.

  8. James Chan

    I feel like they are a solid peptide company. No hitches!

  9. Braxton Tynes

    My only negative with them is I wish I found them sooner.

  10. David Nguyen

    It is a solid company.

  11. Paul Allen

    This product is difficult to look for but they always have it here. Never have to worry about quality control. Really pleased with the variety of options. Definitely recommend ordering from here.

  12. Sarah Wyatt

    Product comes as pictured in the advertisement. Came on time and in great condition.

  13. Beatriz Davis

    I notcied they restock on peptides quickly but also noticed they don’t have a way to communicate a restock either. Just a tip for future refrence.

  14. Jack Taylor

    Bac water they send for free is actually really good quality as well. I see they value having high value products.

  15. Matt Bouser

    Have not had a bad moment with them yet

  16. Luna Torres

    After testing out a few different sellers and Biotech, I have concluded that biotechs service and peptides are by far the best for me and my needs. Prices are not too bad and overall good company.

  17. Briar Castillo

    Biotech is my favorite peptide supplier. Never had a time where what I needed was out of stock.

  18. Loyd williamson

    I have not had a bad experince with Biotech. The peptides meet my standards.

  19. Piage Johnson

    Biotech has been my peptide supplier since the beginning of the year. They have great response time and the representatives are always helpful.

  20. ronald hawkins

    Checkout was quick and easy, nothing too complicated.

  21. Ryan razon

    There seemed to be a mistake on my order where I receievd the wrong order. The process of getting in contact with someone was not difficult. Within 15 minutes me and Danny had it all sorted out and they quickly shipped out the correct peptide.

  22. Mark Sterling

    Peptides are top teir!

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