Selank (10mg)

(22 customer reviews)


Selank peptides are Synthesized and Lyophilized in the USA.

Discount per Quantity

Quantity 5 - 910 +
Discount 5%10%
Price $43.70$41.40
Orders over $200 receive:
FREE - 30ml bottle of bacteriostatic water
(Required for reconstitution)
FREE - USPS priority shipping
SKU: Selank-10mg Category:


Selank Peptide

Selank is a small peptide studied for its potential nootropic and anxiolytic characteristics. It is a synthetic analog of naturally occurring Tuftsin, an immunomodulatory peptide regulating T helper cells, IL-6, monoamine neurotransmitters, and brain-derived neurotrophic factor (BDNF). Selank differs in structure from the endogenous Tuftsin by the additional four amino acids in its chain, which have been supposed to enhance the metabolic stability and half-life of the synthetic peptide.


Molecular Formula: C33H57N11O9

Molecular Weight: 751.89 g/mol

Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro

Selank Research

Selank and GABA Neurotransmitters
As per Dr. Anastasiya Volkova of the Institute of Molecular Genetics in Russia, “numerous clinical studies have [suggested] that Selank has strong antianxiety and neuroprotective effects in the [context] of anxiety. Selank and classical antianxiety [compounds] such as benzodiazepine have a similar mode of action. Selank allosterically modulates GABAA receptors and increases the inhibitory action of GABA.” Researchers like Dr. Volkova have suggested that as a result of peptide activity, stress hormone levels may reduce. Studies focused on small concentrations of Selank exposure have reported a sedating effect similar to benzodiazepines. However, unlike the latter, it appears to be neither habit-forming nor leading to symptoms of withdrawal or amnesia. It has been suggested to influence the expression of 7 genes, moderately affect the expression of 45 other targets, all from a set of roughly 84 genes considered to be involved in GABA signaling.[1] The researchers reported that their “results showed that Selank caused a number of alterations in the expression of genes involved in neurotransmission.” They suggested the peptide may stimulate gene expression in neurons and influence affinity of GABA receptors for GABA. Synergism between Selank and benzodiazepines and other GABA receptor agonists appears to be mediated through alteration of the receptor affinity. Research in rats observes that Selank and benzodiazepines, when alone, appear to have similar impacts on stress hormones, particularly in the case of generalized anxiety disorder. The combined introduction of the two may address unpredictable chronic mild stress, despite Selank’s potential to be better equipped than benzodiazepines. The synergistic potential of these compounds has not been ascertained.[2] The impact of Selank on enkephalin degradation appears to modulate its influence on GABA receptors to a certain extent. Studies have suggested enkephalins with shorter blood stability is present in models of anxiety and phobic disorders. This is apparently caused by increased enkephalinase activity in blood, which may degrade the enkephalins. Studies in murine models of anxiety posit that the peptide appears to inhibit enkephalinase, stabilize enkephalins, reset the enzymatic pathway, and thus may preserve natural anxiolytic peptides.[3]

Selank Peptide and the Immune System in Anxiety
Selank has been studied for its potential to inhibit the gene responsible for the production of the inflammatory cytokine IL-6 in research models of depression, but not in control models.[4] Researchers also note that “the adaptogenic properties of selank may be beneficial [in the cases of exposure] to environmental stressors for the prevention of infectious diseases.” Thus it may be useful in models of anxiety-asthenic disorders, severe anxiety, fatigue, headache, heart palpitations, high blood pressure, nerve pain, and depression. Compared to standard anxiolytic compounds, like benzodiazepines, Selank research suggests it may improve asthenic symptoms such as fatigue and pain perception.[5] This may be due to its apparent stabilization of enkephalins and modification of expression of IL-6. The peptide appears to affect expression of nearly 34 genes in the inflammatory pathway including those affecting chemokines, cytokines, and receptors. Specifically, it has been studied in relation to Bcl6 expression which is considered to promote immune development. This scientific study not only helps to reveal the complex biological impact of the peptide but also may improve our understanding of the immune system. Selank and its truncated versions may mediate transient gene expression for C3, CAsp1, Il2rf, and Xcr1 in the mouse spleen. Selank may therefore alter the balance of the immune system and thereby modulate inflammation.[6]

Selank Peptide and Memory, Learning
Anxiety and learning/memory show a strong inverse association. The peptide appears to reduce the impact of anxiety on cognitive function. Selank research has suggested that the peptide may improve memory traceability and storage in rats.[7] This improvement was independent of the anxiety levels of the rats. The peptide appears to trigger better memory recall through the hippocampal expression of 36 different genes. The majority of the targets are membrane-associated proteins and regulate ion movement across cell membranes. Thus the ion-dependent processes in learning and memory appear to be enhanced by the molecule. Selank researchers have posited its potential towards helping in easy formation and access of memories. It may also help to rescue memory and cognitive abilities after injury in rats exposed to neurotoxins. This inference is considered to be due to the apparent inhibition of catecholamines in the brain.[8] Selank may thereby assist in restoring cognitive function after an injury.

Selank Peptide and Pain Perception
Enkephalins are natural peptides that are considered to reduce the severity of pain by interacting with opioid receptors. Their levels appear high in the brain and adrenal glands during the stress response. Selank may potentially reduce the levels in the brain, which may thereby surpress stress response.

Disclaimer: The products mentioned are not intended for human or animal consumption. Research chemicals are intended solely for laboratory experimentation and/or in-vitro testing. Bodily introduction of any sort is strictly prohibited by law. All purchases are limited to licensed researchers and/or qualified professionals. All information shared in this article is for educational purposes only.



  1. Volkova A, Shadrina M, Kolomin T, Andreeva L, Limborska S, Myasoedov N, Slominsky P. Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission. Front Pharmacol. 2016 Feb 18;7:31. doi: 10.3389/fphar.2016.00031. PMID: 26924987; PMCID: PMC4757669.
  2. Kasian A, Kolomin T, Andreeva L, Bondarenko E, Myasoedov N, Slominsky P, Shadrina M. Peptide Selank Enhances the Effect of Diazepam in Reducing Anxiety in Unpredictable Chronic Mild Stress Conditions in Rats. Behav Neurol. 2017;2017:5091027. doi: 10.1155/2017/5091027. Epub 2017 Feb 9. PMID: 28280289; PMCID: PMC5322660.
  3. Sokolov OY, Meshavkin VK, Kost NV, Zozulya AA. Effects of Selank on behavioral reactions and activities of plasma enkephalin-degrading enzymes in mice with different phenotypes of emotional and stress reactions. Bull Exp Biol Med. 2002 Feb;133(2):133-5. doi: 10.1023/a:1015582302311. PMID: 12432865.
  4. Uchakina ON, Uchakin PN, Miasoedov NF, Andreeva LA, Shcherbenko VE, Mezentseva MV, Gabaeva MV, Sokolov OIu, Zozulia AA, Ershov FI. [Immunomodulatory effects of selank in patients with anxiety-asthenic disorders]. Zh Nevrol Psikhiatr Im S S Korsakova. 2008;108(5):71-5. Russian. PMID: 18577961.
  5. Zozulia AA, Neznamov GG, Siuniakov TS, Kost NV, Gabaeva MV, Sokolov OIu, Serebriakova EV, Siranchieva OA, Andriushenko AV, Telesheva ES, Siuniakov SA, Smulevich AB, Miasoedov NF, Seredenin SB. [Efficacy and possible mechanisms of action of a new peptide anxiolytic selank in the therapy of generalized anxiety disorders and neurasthenia]. Zh Nevrol Psikhiatr Im S S Korsakova. 2008;108(4):38-48. Russian. PMID: 18454096.
  6. Agapova TIu, Agniullin IaV, Silachev DN, Shadrina MI, Slominskiĭ PA, Shram SI, Limborskaia SA, Miasoedov NF. [Effect of semax on the temporary dynamics of brain-derived neurotrophic factor and nerve growth factor gene expression in the rat hippocampus and frontal cortex]. Mol Gen Mikrobiol Virusol. 2008;(3):28-32. Russian. PMID: 18756821.
  7. Semenova TP, Kozlovskiĭ II, Zakharova NM, Kozlovskaia MM. [Experimental optimization of learning and memory processes by selank]. Eksp Klin Farmakol. 2010 Aug;73(8):2-5. Russian. PMID: 20919548.
  8. Semenova TP, Kozlovskaya MM, Zakharova NM, Kozlovskii II, Zuikov AV. Effect of selank on cognitive processes after damage inflicted to the cerebral catecholamine system during early ontogeny. Bull Exp Biol Med. 2007 Nov;144(5):689-91. doi: 10.1007/s10517-007-0406-2. PMID: 18683497.
All orders ship same day if placed by 12 PST.
This product is strictly for research/laboratory use only.  Human or animal use and/or consumption is strictly prohibited by law.  Only qualified and licensed professionals should handle these products.  Any information found on Biotech Peptides is strictly for educational purposes only.  Refer to our terms and conditions for more details.

Additional information


Biotech Peptides

22 reviews for Selank (10mg)

  1. Lucas Allen

    I work as an assistant tech in a lab at my local university and my professor and I were very pleased with the results.

  2. Levi Morris

    Such a great selection and very fair prices.

  3. Landon Gibson

    honestly I was a bit skeptical ordering these kinds of products from the internet as I usually get it from a compounding pharmacy but i am thoroguhly impresed.

  4. Theo McLean

    Very easy ordering and checkout process

  5. Li Westenfelt

    I can’t wait for my package to get here. Thank you guys for a smooth process

  6. River Brooks

    Without a question, the top website for peptides in the industry. Service was great! products were the best quality i’ve come by. Would recommend to others!

  7. Levi Morris

    You guys were able to refund my order in full, Thanks for that. They do stand by their word. I had placed an order for Selank and typically they get this all sent out and delivered within a few days of placing the order. This time around I never got an e-mail stating my peptides have been shipped or even preparing to be delivered. A few days went by and I e-mailed them to ask about my missing peptides. Turns out they were out of stock and someone forgot to e-mail me informing me of the issue. They offered a full refund or to send out the order once they get it in but I went with getting my money back.

  8. James Chan

    I feel like they are a solid peptide company. No hitches!

  9. Braxton Tynes

    My only negative with them is I wish I found them sooner.

  10. David Nguyen

    It is a solid company.

  11. Paul Allen

    This product is difficult to look for but they always have it here. Never have to worry about quality control. Really pleased with the variety of options. Definitely recommend ordering from here.

  12. Sarah Wyatt

    Product comes as pictured in the advertisement. Came on time and in great condition.

  13. Beatriz Davis

    I notcied they restock on peptides quickly but also noticed they don’t have a way to communicate a restock either. Just a tip for future refrence.

  14. Jack Taylor

    Bac water they send for free is actually really good quality as well. I see they value having high value products.

  15. Matt Bouser

    Have not had a bad moment with them yet

  16. Luna Torres

    After testing out a few different sellers and Biotech, I have concluded that biotechs service and peptides are by far the best for me and my needs. Prices are not too bad and overall good company.

  17. Briar Castillo

    Biotech is my favorite peptide supplier. Never had a time where what I needed was out of stock.

  18. Loyd williamson

    I have not had a bad experince with Biotech. The peptides meet my standards.

  19. Piage Johnson

    Biotech has been my peptide supplier since the beginning of the year. They have great response time and the representatives are always helpful.

  20. ronald hawkins

    Checkout was quick and easy, nothing too complicated.

  21. Ryan razon

    There seemed to be a mistake on my order where I receievd the wrong order. The process of getting in contact with someone was not difficult. Within 15 minutes me and Danny had it all sorted out and they quickly shipped out the correct peptide.

  22. Mark Sterling

    Peptides are top teir!

Add a review