Sermorelin (5mg)

(18 customer reviews)


Sermorelin peptides are Synthesized and Lyophilized in the USA.

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Sermorelin Peptide

Sermorelin is among the growth hormone-releasing hormone (GHRH) analogs. It is classified as a GHRH as researchers have suggested that the peptide acts to induce the endogenous production and release of growth hormone (hGH). Growth hormone has been associated with numerous physiological activities, making Sermorelin and other GHRH analogs, potentially relevant in growth hormone-related research. Examples of of studies employing GHRH analogs include research in the context of tissue scarring following cardiac disfunction, as well as those examining bone density, renal function, dementia and seizure activity.


Molecular Formula: C149H246N44O42S

Molecular Weight: 3357.9 g/mol

Sequence: Tyr-Ala-Asp-Ala-lle-Phe-DL-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2

Sermorelin Research

Sermorelin and Cardiac Function
Heart attacks may induce secondary cardiac failure, cardiac conduction abnormalities (arrhythmias), and decreased cardiac capacity. Many of these risks have been associated with cardiac remodeling due to damaged myocytes (heart muscle cells), and may impact surrounding tissues. In 2016, a study in pigs observed that Sermorelin exposure appeared to reduce the instances of cardiac remodeling exhibited following a cardiac attack. Researchers suggested as a result of these findings that the peptide may have acted to decrease cell death in cardiomyocytes, as well as improve production of extracellular matrix components and angiogenesis to damaged tissue. The peptide has also been studied for its potential to assist in diastolic function, decrease scar size, and increase capillary growth.[1] [2] The researchers note that “[Exposure to] GHRH agonists appears to reduce the inflammatory responses post-MI and may consequently improve mechanisms of healing and cardiac remodeling by regulating pathways involved in fibrosis, apoptosis and cardiac repair.” It is being explored for different cardiac diseases like a cardiac failure and valve disorders.

Sermorelin and Epilepsy
Gamma-aminobutyric acid (GABA) is a central nervous system signaling molecule that researchers consider may decrease electrical activity in the spinal cord and reduce overall electrical excitability in the central nervous system. Many anti-seizure compounds act either to: enhance levels of GABA in the central nervous system; or mimic GABA by binding to GABA. In one study using a murine model of epilepsy, scientists introduced Sermorelin to study the impact on the models’ seizure activity. GHRH analogs were observed to activate GABA receptors and inhibit seizures.[3]

Sermorelin and Sleep
Orexin is a powerful neurochemical secreted by certain neurons in the brain. It has been suggested to regulate sleep cycles. Growth hormone secretion, in parallel, is considered to occur maximally during sleep. Studies have suggested that a functional GHRH axis is required for orexin production and function, and that exposure to Sermorelin and other GHRH agonists appears to enhance orexin secretion.[4] Sermorelin is being studied in the context of sleep disorders.

Sermorelin and Growth Hormone
Sermorelin is a growth hormone-releasing hormone derivative that was developed to mediate the activity of growth hormone, with limited ancillary effects. Sermorelin has been studied for its potential to increase hormone levels as the peptide appears to be regulated through physiological feedback mechanisms that prevent certain ancillary actions of excess growth hormone. Such actions may include instances of edema, joint pain, and dysregulation of normal physiology.[5] Sermorelin researchers have posited that the peptide may not be subject to tachyphylaxis, the process by which the body becomes acclimatized to a compound and thereby negates its action.[6] Scientists conclude that “that the short time course of resensitisation following acute octreotide withdrawal is suggestive of an effect(s) on receptor function or on the receptor signal transduction cascade at sites further downstream, rather than an immune-mediated phenomenon.” Studies have suggested peptide-induced production of GHRH receptors, rather than a down-regulation of them. This action may prevent the onset of tachyphylaxis.

Disclaimer: The products mentioned are not intended for human or animal consumption. Research chemicals are intended solely for laboratory experimentation and/or in-vitro testing. Bodily introduction of any sort is strictly prohibited by law. All purchases are limited to licensed researchers and/or qualified professionals. All information shared in this article is for educational purposes only.



  1. Bagno LL, Kanashiro-Takeuchi RM, Suncion VY, et al. Growth hormone-releasing hormone agonists reduce myocardial infarct scar in swine with subacute ischemic cardiomyopathy. J Am Heart Assoc. 2015;4(4):e001464. Published 2015 Mar 31. doi:10.1161/JAHA.114.001464.
  2. Kanashiro-Takeuchi RM, Szalontay L, Schally AV, et al. New therapeutic approach to heart failure due to myocardial infarction based on targeting growth hormone-releasing hormone receptor. Oncotarget. 2015;6(12):9728-9739. doi:10.18632/oncotarget.3303.
  3. Tang S, Luo Z, Qiu X, et al. Interactions between GHRH and GABAARs in the brains of patients with epilepsy and in animal models of epilepsy. Sci Rep. 2017;7(1):18110. Published 2017 Dec 22. doi:10.1038/s41598-017-18416-5.
  4. Shepherd BS, Johnson JK, Silverstein JT, et al. Endocrine and orexigenic actions of growth hormone secretagogues in rainbow trout (Oncorhynchus mykiss). Comp Biochem Physiol A Mol Integr Physiol. 2007;146(3):390-399. doi:10.1016/j.cbpa.2006.11.004.
  5. Walker RF. Sermorelin: a better approach to management of adult-onset growth hormone insufficiency?. Clin Interv Aging. 2006;1(4):307-308. doi:10.2147/ciia.2006.1.4.307.
  6. Wahid ST, Marbach P, Stolz B, Miller M, James RA, Ball SG. Partial tachyphylaxis to somatostatin (SST) analogues in a patient with acromegaly: the role of SST receptor desensitisation and circulating antibodies to SST analogues. Eur J Endocrinol. 2002;146(3):295-302. doi:10.1530/eje.0.1460295.
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18 reviews for Sermorelin (5mg)

  1. Hughes Evelyn

    Thumbs up for amazing service

  2. Eleanor Calder

    Great product. Honest seller.

  3. Mila Atken

    A+ service and quality

  4. Laurie Barnes

    Shipping was fast. sent out the same day.

  5. Jennifer Vachon

    If you are new like I was, I highly recommend you give them a try. You won’t regret it.

  6. Nathan Cragun

    If I could rate them higher I would

  7. Esther C.

    Incredibly swift and smooth ordering process, professional communication, and excellent quality of products.

  8. Brent Wolfe

    Packaging is always discreet and tamper evident. They go the extra mile.

  9. Kelli Dougal

    Pleasure working with them. Had a few vials come in broken! Called them and they were able to get new ones sent over.

  10. John Rowekamp

    Love that it’s a local and reliable company, I get shipments super fast and happy I don’t need to order from out of state!

  11. Addison Long

    I like that they send out promo codes as often as they can. They are already one of the cheapest places to buy peptides but that extra little money saver is excellent!

  12. Phil W.

    I recently bought peptides from Biotech. They came highly recommended to me and I can see why.

  13. Nick kesler

    Biotech has great service! Dani is the person I bother for everything weather its to fix a mistake on my end or to place a big order that could be more difficult to do online.

  14. antonio ricci

    As far as peptide companies go, they are the best I have found in the past 5 years. They are not that old of a company but they’re beating out the ones that are.

  15. Connie Aracena

    Peptides are okay for the cost, and so far I have had no reason to contact customer service.

  16. Nikko Guzman

    Satisifed customer. From begining to end had great customer service and the peptides are perfect for what they cost.

  17. Andy Benavides

    Smooth and fast check out process! No extra loops to jump over when checking out.

  18. Stepan Thorn

    New to peptide research and a friend actually recommended them. Have been doing some research and they have the best priced Peptides around and the products are of the highest quality. Looking forward to getting to use them and see what they can do for my research.

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