No products in the cart
TB-500 (Thymosin Beta-4) (10mg)
$119.00
TB-500 peptides are Synthesized and Lyophilized in the USA.
Discount per Quantity
| Quantity | 5 - 9 | 10 + |
|---|---|---|
| Discount | 5% | 10% |
| Price | $113.05 | $107.10 |
FREE - 30ml bottle of bacteriostatic water
(Required for reconstitution)
FREE - USPS priority shipping
Description
TB-500 (Thymosin Beta-4) Peptide
TB-500, or Thymosin Beta-4, is a synthetic analog of the endogenous Thymosin proteins, which are considered ubiquitously present in cells. The peptide belongs to a widespread family of 16 related molecules considered to exhibit a high degree of sequence conservation and localization in the majority of the tissues and circulating cells. TB-500 was developed with the intention of sequestering and blocking actin polymerization in eukaryotic cells.
Specifications
Other Known Titles: Thymosin Beta-4
Molecular Formula: C212H350N56O78S
Molecular Weight: 4963.506 g/mol
Sequence: Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-lle-GluLys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-LysThr-Glu-Thr-Gin-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-GluThy-lleGlu-Gin-Glu-Lys-Gin-Ala-Gly-Glu-Ser
TB-500 (Thymosin Beta-4) Research
TB-500, or Thymosin Beta-4 expression appears to increase four-six fold during early angiogenesis. Research suggests it may promote the growth of new blood cells from existing vessels, and thereby potentially mediate faster tissue repair.[1] Researchers point out that “Delineating the molecular pathways impacted by Tβ4 to promote vascular growth and remodeling may reveal novel targets for prevention … of vascular disease.” The actin-binding domain happens to be a short central stretch of amino acid. It appears to be involved in TB-500-mediated regulation of blood cell division, tissue repair processes, migration of endothelial cells and keratinocytes, and possibly also higher production of extracellular matrix-degrading enzymes.
TB-500 research suggests the peptide’s potential anti-inflammatory characteristics.[2] According to the research, “It acts by increasing angiogenesis and cell migration and is currently [studied in] wound repair.” TB-500, unlike other naturally produced growth factors, may possibly support endothelial and keratinocyte migration. It also does not appear to bind to the extracellular matrix, and researchers suggest that its low molecular weight may help it travel comparatively long distances through tissues. Study findings typically hypothesize the action of the peptide may be to regulate the polymerization and function of actin.
Disclaimer: The products mentioned are not intended for human or animal consumption. Research chemicals are intended solely for laboratory experimentation and/or in-vitro testing. Bodily introduction of any sort is strictly prohibited by law. All purchases are limited to licensed researchers and/or qualified professionals. All information shared in this article is for educational purposes only.
References
- Dubé, K. N., & Smart, N. (2018). Thymosin β4 and the vasculature: multiple roles in development, repair and protection against disease. Expert opinion on biological therapy, 18(sup1), 131–139. doi:10.1080/14712598.2018.1459558
- Philp, D., Goldstein, A. L., & Kleinman, H. K. (2004). Thymosin beta4 promotes angiogenesis, wound healing, and hair follicle development. Mechanisms of ageing and development, 125(2), 113–115. doi:10.1016/j.mad.2003.11.005
- Maar K, Hetenyi R, Maar S, et al. Utilizing Developmentally Essential Secreted Peptides Such as Thymosin Beta-4 to Remind the Adult Organs of Their Embryonic State-New Directions in Anti-Aging Regenerative Therapies. Cells. 2021;10(6):1343. Published 2021 May 28. doi:10.3390/cells10061343
- Malinda, K. M., Sidhu, G. S., Mani, H., Banaudha, K., Maheshwari, R. K., Goldstein, A. L., & Kleinman, H. K. (1999). Thymosin beta4 accelerates wound healing. The Journal of investigative dermatology, 113(3), 364–368. doi:10.1046/j.1523-1747.1999.00708.x
- Song, R., Choi, H. M., Yang, H. I., Yoo, M. C., Park, Y. B., & Kim, K. S. (2012). Association between serum thymosin β4 levels of rheumatoid arthritis patients and disease activity and response to therapy. Clinical rheumatology, 31(8), 1253–1258. doi:10.1007/s10067-012-2011-7
All orders ship same day if placed by 12 PST.
This product is strictly for research/laboratory use only. Human or animal use and/or consumption is strictly prohibited by law. Only qualified and licensed professionals should handle these products. Any information found on Biotech Peptides is strictly for educational purposes only. Refer to our terms and conditions for more details.
Dr. Usman (BSc, MBBS, MaRCP) completed his studies in medicine at the Royal College of Physicians, London. He is an avid researcher with more than 30 publications in internationally recognized peer-reviewed journals. Dr. Usman has worked as a researcher and a medical consultant for reputable pharmaceutical companies such as Johnson & Johnson and Sanofi.
Additional information
| Brand | Biotech Peptides |
|---|
13 reviews for TB-500 (Thymosin Beta-4) (10mg)
You must be logged in to post a review.
Jade Peterson –
Amazing products and value. Very fast response and shipping. I am very pleased with the experience
Mason Webb –
One of the leading suppliers in peptides. Very qualitative products
Parker Findlay –
The quantity variations of the same products are very helpful and nice
Astrid Duncan –
Had the peptide I needed in stock. Appreciate the coupon code as well.
Jenifer Smith –
Just placed an order yesterday. this morning received an email from their rep telling me they are out of stock of it at the moment but will place it as soon as it’s in. It’s slightly frustrating. Just glad someone reached out instead of leaving me wondering what happened to my order.
Taryn Alvarado –
They have great response times, friendly staff, and most importantly knowledgable staff! They are trained to know their stuff!!
Orion Quinn –
The whole process was quick and easy.
Mario Salvado –
The peptides are typically always stocked. Rare I have encountered one out of stock when it’s time to rebuy.
coleen mcelroy –
Taylor was able to help me place a big order for our lab site. They worked with me and let me know if there was any substitues for peptides that they had out of stock as well! Prices are one of the best I have found as well when shopping around.
Harper Santos –
Purest peptides on the market right now.
Nikkie Wong –
Peptides work well with my specific research. This was my first time purchasing so I will definitely revisit!
Eitan Assil –
Very happy to have found Biotech. Peptides are sold at a great price and the service you recieve is probably the best I have ever gotten anywhere.
Ace Brashear –
Appreciate the discount code you sent after my 10th purchase!!