Mod GRF 1-29 & Ipamorelin Blend (10mg)

(29 customer reviews)


Mod GRF (1-29) & Ipamorelin blend is Synthesized and Lyophilized in the USA.

Discount per Quantity

Quantity 5 - 910 +
Discount 5%10%
Price $76.95$72.90
Orders over $200 receive:
FREE - 30ml bottle of bacteriostatic water
(Required for reconstitution)
FREE - USPS priority shipping
SKU: Mod-GRF-1-29-Ipamorelin-10mg Category:


What is the Mod GRF (1-29) & Ipamorelin Peptide Blend?

Mod GRF (1-29) & Ipamorelin are two peptides reported to posess similar functions, and work synergistically. Together, these peptides have the potential to trigger growth hormone release and stimulate the growth hormone pulses. This increase may result in the physiological benefits associated with increased growth hormone release, such as improved growth, vitality, mental clarity, and overall health. Mod GRF (1-29) peptide is an analog of growth hormone-releasing hormone (GHRH).[1] Similarly, Ipamorelin is suggested to act via binding to growth hormone secretagogue receptors.[2] Generally, GRF has a short half-life that limits its therapeutic potential. However, GRF (1-29) has a modified structure with an apparent longer half-life and therefore better therapeutic potential. Likewise, Ipamorelin appears to have a high sensitivity to growth hormone receptors, leading to superior therapeutic outcomes. Mixing these peptides into a single blend may lead to a better growth hormone response. Research suggests that using the blend of Mod GRF (1-29) & Ipamorelin may lead to better outcomes than using either of these peptides alone. These outcomes may include improved memory, higher glucose control, enhanced post-workout recovery, lean muscle gain, and improved overall health.

Mod GRF 1-29 Specifications

Molecular Formula: C152H252N44O42

Molecular Weight: 3367.95 g/mol

Sequence: H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2

PubChem: CID 56841945

CAS Number: 863288-34-0

Reconstitution: Required

Ipamorelin Specifications

Molecular Formula: C38H49N9O5

Molecular Weight: 711.85 g/mol

Sequence: Aib-His-D-2Nal-D-Phe-Lys-NH2

PubChem: CID 9831659

CAS Number: 170851-70-4

Reconstitution: Required


Mod GRF 1-29 & Ipamorelin – Research in Gastrointestinal Health
Research suggests that GH may have positive effects on inflammatory bowel disease (especially Crohn’s disease) and short bowel syndrome.[3] Researchers report that “65% of patients receiving GH achieved clinical remission, compared to 20% treated with CTX alone.” GH acts via Vasoactive Intestinal Peptide (VIP) receptor VIPC1. This interaction allows GH to improve bowel motility and constipation, a major issue in inflammatory bowel disease.

Mod GRF 1-29 & Ipamorelin – Research in Cardiac Health
Myocardial Infarction (MI) leads to the scarring of cardiac tissues and reduces heart function (such as ejection fraction); Studies in animal models have suggested the benefits of GH, stimulating therapies in improving heart health following MI. GH analogs may accelerate heart tissue repair post-MI, reduce infarct size, improve cardiac ejection fraction, and improve overall cardiac health.[4] The scientists reveal that “Through activation of GHS-R1a, secretagogues produced a positive inotropic effect on ischemic cardiomyocytes and protected them from I/R injury probably by protecting or recovering p-PLB (and therefore SR Ca2+ content) to allow the maintenance or recovery of normal cardiac contractility.”

Mod GRF 1-29 & Ipamorelin – Research in Bone Health
Issues associated with bone health, such as osteoporosis, are a major public health concern. Therapies such as bisphosphonates, monoclonal antibodies, and hormone therapies are approved methods for treating osteoporosis. These therapies are effective, but serious side effects limit their efficacy. In comparison, GH stimulating peptides such as Mod GRF (1-29) and Ipamorelin may become an inexpensive therapy with the potential to improve bone health with an excellent safety profile. Long term use of corticosteroids is one of the biggest risk factors for accelerated osteoporosis. Research in animal models suggests that GH-stimulating peptides such as Ipamorelin may completely halt the bone loss triggered by steroids.[5] Moreover, it may trigger new bone formation and increase the Bone Mineral Density (BMD) by four-fold. An increase in BMD would improve bone quality and strength, and reduce the risk of osteoporosis complications such as fragility fractures.

Mod GRF 1-29 & Ipamorelin – Research in Muscle Growth
Research suggests that GH-secretagogues like Ipamorelin may inhibit the catabolic effects of glucocorticoids on muscles (such as muscle wasting).[6] Mod GRF (1-29) & Ipamorelin peptide combination may have a high GH-receptor sensitivity and act via mechanisms including increased levels of Insulin-Like Growth Factor 1 (IGF-1), leading to better muscle gain. The potential benefits of this combination make it a valuable therapeutic target for corticosteroid-induced muscle wasting and can stimulate muscle gain post-workout.

Mod GRF 1-29 & Ipamorelin – Research in Blood Sugar Regulation
Diabetes is a condition involving almost all major organs and body systems. Better blood sugar regulation leads to improved morbidity and mortality associated with diabetes. Mod GRF (1-29) & Ipamorelin blend may lead to better diabetes control in various ways. Some research suggests that using GH-analogs may increase the number of beta-pancreatic cells leading to better insulin secretion. Calcium-driven channels mediate insulin secretion from pancreatic cells. GH-secretagogues such as Ipamorelin may trigger insulin release from pancreatic cells by acting on the pancreatic cells’ calcium channels.[7] Therefore, this peptide combination has a therapeutic potential for diabetes management.

Mod GRF 1-29 & Ipamorelin – Research in Management of Postoperative Ileus
Postoperative Ileus (POI) is a common complication following intra-abdominal surgeries. Researchers suggest this peptide combination may significantly reduce the chances of POI and reduce the time to the first meal by approximately 12 hours.[8]

Mod GRF 1-29 & Ipamorelin – Research in Thyroid Health
Thyroid dysfunction occurs concomitantly with growth hormone disturbances. This is especially true for conditions involving the pituitary gland, where thyroid dysfunction is also associated with GH deficiency. Researchers have noticed that individuals with thyroid insufficiency, when given GRF, appear to show a better response to their thyroid replacement.[9]

Mod GRF 1-29 & Ipamorelin – Research in Mental Health
The Mod GRF (1-29) & Ipamorelin peptide combination may affect neurodegenerative conditions and general mental well-being. Research suggests that GH-stimulating therapies can lead to improved neurogenesis and can be a potential therapy for conditions such as dementia and Parkinson’s Disease. In addition, research has also suggested that the use of GH and GH-analogs may improve mental health indicators such as concentration, mental clarity, problem-solving abilities, and etc.


  1. Waelbroeck M, Robberecht P, Coy DH, Camus JC, De Neef P, Christophe J. Interaction of growth hormone-releasing factor (GRF) and 14 GRF analogs with vasoactive intestinal peptide (VIP) receptors of rat pancreas. Discovery of (N-Ac-Tyr1,D-Phe2)-GRF(1-29)-NH2 as a VIP antagonist. Endocrinology. 1985 Jun;116(6):2643-9. doi: 10.1210/endo-116-6-2643. PMID: 2859987.
  2. Raun K, Hansen BS, Johansen NL, Thøgersen H, Madsen K, Ankersen M, Andersen PH. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. 1998 Nov;139(5):552-61. doi: 10.1530/eje.0.1390552. PMID: 9849822.
  3. Denson LA, Kim MO, Bezold R, Carey R, Osuntokun B, Nylund C, Willson T, Bonkowski E, Li D, Ballard E, Collins M, Moyer MS, Klein DJ. A randomized controlled trial of growth hormone in active pediatric Crohn disease. J Pediatr Gastroenterol Nutr. 2010 Aug;51(2):130-9. doi: 10.1097/MPG.0b013e3181c992d6. PMID: 20453679; PMCID: PMC2910806.
  4. Ma Y, Zhang L, Edwards JN, Launikonis BS, Chen C. Growth hormone secretagogues protect mouse cardiomyocytes from in vitro ischemia/reperfusion injury through regulation of intracellular calcium. PLoS One. 2012;7(4):e35265. doi: 10.1371/journal.pone.0035265. Epub 2012 Apr 6. PMID: 22493744; PMCID: PMC3320867.
  5. Svensson J, Lall S, Dickson SL, Bengtsson BA, Rømer J, Ahnfelt-Rønne I, Ohlsson C, Jansson JO. The GH secretagogues ipamorelin and GH-releasing peptide-6 increase bone mineral content in adult female rats. J Endocrinol. 2000 Jun;165(3):569-77. doi: 10.1677/joe.0.1650569. PMID: 10828840.
  6. Sinha DK, Balasubramanian A, Tatem AJ, Rivera-Mirabal J, Yu J, Kovac J, Pastuszak AW, Lipshultz LI. Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males. Transl Androl Urol. 2020 Mar;9(Suppl 2):S149-S159. doi: 10.21037/tau.2019.11.30. PMID: 32257855; PMCID: PMC7108996.
  7. Adeghate E, Ponery AS. Mechanism of ipamorelin-evoked insulin release from the pancreas of normal and diabetic rats. Neuro Endocrinol Lett. 2004 Dec;25(6):403-6. PMID: 15665799.
  8. Beck DE, Sweeney WB, McCarter MD; Ipamorelin 201 Study Group. Prospective, randomized, controlled, proof-of-concept study of the Ghrelin mimetic ipamorelin for the management of postoperative ileus in bowel resection patients. Int J Colorectal Dis. 2014 Dec;29(12):1527-34. doi: 10.1007/s00384-014-2030-8. Epub 2014 Oct 21. PMID: 25331030.
  9. Valcavi R, Jordan V, Dieguez C, John R, Manicardi E, Portioli I, Rodriguez-Arnao MD, Gomez-Pan A, Hall R, Scanlon MF. Growth hormone responses to GRF 1-29 in patients with primary hypothyroidism before and during replacement therapy with thyroxine. Clin Endocrinol (Oxf). 1986 Jun;24(6):693-8. doi: 10.1111/j.1365-2265.1986.tb01666.x. PMID: 3098458.
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Biotech Peptides

29 reviews for Mod GRF 1-29 & Ipamorelin Blend (10mg)

  1. Annie Bardot

    Always a pleasure talking to customer service, Ive had a couple minor issues with USPS but its been resolved by CS with no questions aksed.

  2. Tony West

    After ordering from here several times I’ve had nothing but good experiences.

  3. Axel Langley

    As described, couldn’t have asked for more. Thanks for the freebie <3

  4. Leif McKenna

    I’ve had concerns regarding sanitation with other suppliers but everything came packaged really professionally.

  5. Brantley Daughtler

    love the product

  6. Penny King

    Danny was super helpful and was the one who contacted me when something was wrong with my payment. They made the process easy and just took payment over the phone which was great since I wasn’t near a computer at the moment.

  7. Jonathan Ottensooser

    They went above and beyond to help me. Had a problem with my payment. They reached out by phone to inform me of the problem and handled it right away. The guy even explained to me how to avoid this ordeal the next time I place an order. The best part was I got my order on schedule.

  8. Reece Lam

    This was my first time ordering from Biotech Peptides! Only slightly disappointed that a few products I needed were out. I did see a few others I was running low on so decided to order does instead. Hoping I have a good experience with shipping and quality.

  9. Daniella Navarro

    Siempre es un gran placer comprar aquí.

  10. Taj Khan

    Superior company. No words

  11. Alex Bartram

    No words needed. I’ll let the review speak for itself

  12. Diego Sanchez

    Muy buena compañia

  13. Andre Mac

    Have’t experinced the service you get at Biotech at any other Peptide business.

  14. Harlow Pham

    The delivery time took me by surprise. Cannot believe how fast they work

  15. Laura Perry

    Only thing I have to say is wish they would email or have a waitlist or soemthing to notify me when product is back in stock. Other than that I have no other complinats.

  16. Issac Kim

    I wish I discovered you earlier. Would’ve saved me a lot of bad peptides and experiences


    I suggest them to co-workers when they ask for a peptide source referral.

  18. Elija Stevenson

    This blend is simply the best things I’ve ever come across on this site.

  19. Spencer Noels

    No doubt, the best peptide website on the market. The best products and services available.

  20. Matthew Stahl

    Excellent, 11 out of 10 blend, thanks for making this available.

  21. A. McGill

    Every time I make a call, I receive the greatest service. Shipping is lightning-fast. When a product was damaged in shipping, they immediately replaced it with a new one and didn’t ask any questions.

  22. eric paciello

    I tried a couple peptides from them last month as a test run. No things were damaged or lost in the delivery.

  23. Mac Weissman

    I honestly feel like your prices are a bit too high. I understand the price-quality ratio thing, but some of the scores on here are immense. Might wanna reconsider a bit.

  24. Joey Ablouh

    Nice selection of peptides, prices are fair too

  25. Erick Richardson

    This is how you do business. Astonishing quality and amazing prices!

  26. Jose Lima

    This is the nicest blend I have ever tested out

  27. Jordan Rosales

    Tuve la mejor experiencia con ellos hasta ahora. seguiré comprando

  28. Devin Roberts

    They’re a good place to get peptides from. Peptides are of good quality. Have had no issues with regards to purity. Shipping is the same as everywhere as well nothing too special or different.

  29. Chuck Yates

    Definitely know how to keep your customers coming back. From the best products on the market too well trained employees.

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