Fragment 176-191 & CJC-1295 & Ipamorelin Blend (12mg)

(21 customer reviews)

$76.00

Fragment 176-191 & CJC-1295 & Ipamorelin Blend are Synthesized and Lyophilized in the USA.

Discount per Quantity

Quantity5 - 910 +
Discount5%10%
Price$72.20$68.40
Orders over $200 receive:
FREE - 30ml bottle of bacteriostatic water
(Required for reconstitution)
FREE - USPS priority shipping
SKU: Fragment-176-191-CJC-1295-Ipamorelin-12mg Category:

Description

Fragment 176-191 Specifications

AKA : Frag 176-191

Molecular Formula : C78H125N23O23S2

Molecular Weight : 1817.1 g/mol

Sequence : Tyr-Leu-Arg-Ile-Val-Gin-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe

CAS Number : 66004-57-7

Reconstitution : Required

CJC-1295 Specifications

Molecular Formula: C152H252N44O42

Molecular Weight: 3647.954 g/mol

Sequence: H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-Lys(Mal)-NH2

PubChem: CID 56841945

Reconstitution: Required

Other: DOES NOT CONTAIN DAC

Ipamorelin Specifications

Molecular Formula: C38H49N9O5

Molecular Weight: 711.85 g/mol

Sequence: Aib-His-D-2Nal-D-Phe-Lys-NH2

PubChem: CID 9831659

CAS Number: 170851-70-4

Reconstitution: Required

Potential of Fragment 176-191 & CJC-1295 & Ipamorelin Peptide Blend

Studies in animal models have suggested the efficacy of Fragment 176-191, a short stretch of human growth hormone (HGH), in promoting fat mobilization and triggering a metabolic shift towards the perpetuation of lean body mass.[1] It appears to further lack the side effects of hGH such as long-bone growth, reduced sensitivity to insulin, edema, and promotes cartilage regeneration. It has been reported by researchers to boost the body’s natural immune system and metabolic processes. The peptide fragment has also been observed to promote GH secretion by regulating physiological processes involved in GH synthesis. The scientifically-studied potential of Fragment 176-191 include effective fat burning via increased lipolysis and decreased lipogenesis and adequate energy levels.[2] It does not appear to significantly alter glucose tolerance, insulin sensitivity, or IGF-1 levels, though more research is needed to validate any claims. Fragment 176-191 may also play a role in benefiting the treatment of other diseases, beyond it’s potential in obesity therapy. Potential areas of research include using Fragment 176-191 as a treatment option for prediabetes and diabetes. Due to its supposed cartilage regeneration abilities, experts may also consider it in adjunctive therapy for osteoarthritis treatment.

CJC-1295 is another synthetic GH releasing hormone. It appears to promote the production of GH and can be used as an alternative for Fragment 176-191 concerning GH synthesis.[3] CJC-1295 has been primarily researched for its anti-aging potential. CJC-1295 may improve basal as well as highest physiological levels of GH. It may further increaase the availability of free GH in plasma. Numerous studies have suggested that CJC-1295 has helped reduce weight and attain a healthier body. CJC-1295 also appears to have healing properties due to its possible cell replication and regeneration abilities. Only the freely available GH happens to be functional in the body. The use of CJC-1295 thus may help to adjust the natural physiological reaction to Fragment 176-191. Therefore, Fragment 176-191 may potentially be used by the body for its other benefits without altering the physiological levels of GH. Therefore, by regulating growth hormone production in the body, CJC-1295 may possibly benefit the ill effects of aging attributed to decreased growth hormone production in the body. Studies have suggested that it may improve injury recovery time and possess beneficial effects on sleep and cognitive function.[4]

Ipamorelin is a peptide that apparently functions as an agonist for the GH secretagogue receptor. It may be administered in combination with Fragment 176-191 and CJ-1295 to potentially enhance the secretion of GH and maximize its physiological level. Animal studies have suggested Ipamorelin to be beneficial in regulating insulin and bone mineralization.[5] The researchers reported that it “stimulates insulin release through the calcium channel and the adrenergic receptor pathways.” Thus, the main effects of Ipamorelin could be on the pancreatic tissue, where it may increase insulin production, release of the ghrelin hormone, and increase cell synthesis. It has been suggested to have numerous other beneficial effects as well. These include the promotion of fat loss, increased testosterone production, improved sexual health, bone strength, and body temperature regulation. Interestingly, it appears to mediate an immediate short-term response, causing a rapid GH release. CJC-1295, by contrast, appears to exercise a long-term influence by enhancing GH secretion over an extended duration and helps maintain standard physiological secretion patterns of GH. Having a half-life of just 2 hours, Ipamorelin may be cleared more rapidly from the body.[6] Keeping in view the pharmacokinetics of the two peptides, researchers have studied them in combination to ensure a rapid response (attributed to Ipamorelin) and long-lasting effects (owing to CJC-1295).

References

  1. Ng FM, Sun J, Sharma L, Libinaka R, Jiang WJ, Gianello R. Metabolic studies of a synthetic lipolytic domain (AOD9604) of human growth hormone. Horm Res. 2000;53(6):274-8. doi: 10.1159/000053183. PMID: 11146367.
  2. Heffernan M, Summers RJ, Thorburn A, Ogru E, Gianello R, Jiang WJ, Ng FM. The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice. Endocrinology. 2001 Dec;142(12):5182-9. doi: 10.1210/endo.142.12.8522. PMID: 11713213.]
  3. Teichman SL, Neale A, Lawrence B, Gagnon C, Castaigne JP, Frohman LA. Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. J Clin Endocrinol Metab. 2006 Mar;91(3):799-805. doi: 10.1210/jc.2005-1536. Epub 2005 Dec 13. PMID: 16352683.
  4. Van Hout MC, Hearne E. Netnography of Female Use of the Synthetic Growth Hormone CJC-1295: Pulses and Potions. Subst Use Misuse. 2016 Jan 2;51(1):73-84. doi: 10.3109/10826084.2015.1082595. Epub 2016 Jan 15. PMID: 26771670.
  5. Adeghate E, Ponery AS. Mechanism of ipamorelin-evoked insulin release from the pancreas of normal and diabetic rats. Neuro Endocrinol Lett. 2004 Dec;25(6):403-6. PMID: 15665799.
  6. Gobburu JV, Agersø H, Jusko WJ, Ynddal L. Pharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide, in human volunteers. Pharm Res. 1999 Sep;16(9):1412-6. doi: 10.1023/a:1018955126402. PMID: 10496658
All orders ship same day if placed by 2pm PST.
This product is strictly for research/laboratory use only.  Human or animal use and/or consumption is strictly prohibited by law.  Only qualified and licensed professionals should handle these products.  Any information found on Biotech Peptides is strictly for educational purposes only.  Refer to our terms and conditions for more details.

Additional information

Brand

Biotech Peptides

21 reviews for Fragment 176-191 & CJC-1295 & Ipamorelin Blend (12mg)

  1. Harry Gagnon

    Very good experience

  2. Ollie Hill

    Great variety of products. A lot to choose from

  3. Samantha Singh

    Impeccable customer service with quick and clear communication every time. When you also consider the transparency offered by this company by way of testing, it’s clear that they are in a league of their own.

  4. Amy Tran

    this is just what I was looking for. thanks a bunch!

  5. Rory Nolan

    Very easy to use for my experiments. So convenient to be able to pay with a credit card. I noticed a lot of the other suppliers do not accept cards!

  6. Carolina A.

    Biotech Peptides products are promising so far. Packages did come later than expected though. But overall, not a bad experience.

  7. Natalie M. Smith

    Decided to try out Biotech after reading the reviews. Was hesitant at first but did not disappoint!

  8. Mark Grondahl

    Amazing product. excited for my next order to come in

  9. Christina Huynh

    Pretty good at keeping products in stock. so far have not had to wait for any restocks and have been a customer for about 6 months now.

  10. Hamala Makala

    Won a retrun customer!

  11. Joe Mick

    they work fast man, ordered it yesterday and got it in today. nice

  12. Jack Newal

    I was hesitant to begin my research with peptides, I read a lot of blogs and reviews and I have to say, I was really scared to order. It’s crazy what you can find out there- People not getting their orders or messegaes answered, never getting their money back. Ordering was a really scary experience, but Biotech is,fortunately, a very reliable company and made the whole process so much more easier. Put my mind at ease and never had an issue

  13. Eric Green

    Biotech hasn’t failed me yet.

  14. Taj Khan

    Entire process from buying to revieving peptides is uncomplicated and stress free.

  15. Sam Everson

    Biotech was recommended to me by a work buddy, they have used them in their projects a few times and swear by their products.

  16. Jose Reyes

    They seem to have a glitch in their system, it was showing me this peptide was in stock so purchased it. Later in the day got an email saying it was actually sold out and their system was not working. I think it was Danni that said they would personaly update me when it was restocked. Holding them to that!

  17. SCOTT MOORE

    I have been using peptides from Biotech over over a year now. Just bought some more peptides as the quality never disapoints.

  18. Leo Marchildon

    Happy customer, orders came in time for my new project. Have a pretty neat collection of peptides on their site. Have a lot to choose from. Have not worked too much with topical peptides but nice to know they also have it here if I decide to ever try those out.

  19. Jack Potter

    The entire process of buying to receiving the peptides is easy. They even save your info for the next purchase.

  20. Dwayne Carter

    Been a loyal customer for over a year, best place to buy in bulk!

  21. Billy Mikles

    Receive my order within three days after purchase so far so good

Add a review