Fragment 176-191 SPECIFICATIONS
AKA : Frag 176-191
Molecular Formula : C78H125N23O23S2
Molecular Weight : 1817.1 g/mol
Sequence : Tyr-Leu-Arg-Ile-Val-Gin-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe
CAS Number : 66004-57-7
Reconstitution : Required
CJC 1295 DAC SPECIFICATIONS
AKA: CJC 1295 with DAC
Molecular Formula: C152H252N44O42
Molecular Weight: 3647.954 g/mol
PubChem: CID 56841945
Molecular Formula: C38H49N9O5
Molecular Weight: 711.85 g/mol
PubChem: CID 9831659
CAS Number: 170851-70-4
Potential of Fragment 176-191 & CJC-1295 & Ipamorelin Blend
Studies in animal models have highlighted the efficacy of Fragment 176-191, a short stretch of human growth hormone (HGH), in promoting fat mobilization and triggering a metabolic shift towards the perpetuation of lean body mass. It further lacks the side effects of hGH such as long-bone growth, reduced sensitivity to insulin, edema, and promotes cartilage regeneration.
It has been shown to boost the body’s natural immune system and metabolic processes. The peptide fragment has also been observed to promote GH secretion by regulating physiological processes involved in GH synthesis. The scientifically-proven benefits of Fragment 176-191 include, effective fat burning via increased lipolysis and decreased lipogenesis and adequate energy levels. It also does not significantly alter glucose tolerance, insulin sensitivity, or IGF-1 levels.
Considering all of its beneficial effects, Fragment 176-191 can play a role in many other diseases rather than being used as an anti-obesity drug. Potential areas of interest include using Fragment 176-191 as a treatment option for prediabetes and diabetes. Due to its cartilage regeneration abilities, experts can also use it in adjunctive therapy for osteoarthritis treatment.
CJC-1295 is another synthetic GH releasing hormone. It promotes the production of GH and can be used as an alternative for Fragment 176-191 concerning GH synthesis. CJC-1295 is majorly an anti-aging peptide. CJ-1295 improves basal as well as highest physiological levels of GH. It further increases the availability of free GH in plasma.
Numerous studies have proven that CJC-1295 has helped reduce weight and attain a healthier body.CJC-1295 also has healing properties due to its cell replication and regeneration properties. Only the freely available GH happens to be functional in the body. The use of CJC-1295 thus helps to adjust the natural physiological reaction to Fragment 176-191. Therefore, Fragment 176-191 can be used by the body for its other benefits without altering the physiological levels of GH.
Therefore, by regulating growth hormone production in the body, CJC-1295 reverses the many ill effects of aging attributed to decreased growth hormone production in the body. Studies have revealed that it improves injury recovery time and has beneficial effects on sleep and cognitive function.
Ipamorelin is a peptide that functions as an agonist for the GH secretagogue receptor. It can be administered in combination with Fragment 176-191 and CJ-1295 to further enhance the secretion of GH and maximize its physiological level. Animal studies have proven Ipamorelin to be beneficial in regulating insulin and bone mineralization.
Thus, the main effects of ipamorelin are on the pancreatic tissue, where it increases insulin production, stomach, where it causes the release of the ghrelin hormone, and increases cell synthesis. It has been shown to have numerous other beneficial effects as well. These include the promotion of fat loss, increased testosterone production, improved sexual health, bone strength, and body temperature regulation.
Interestingly, it mediates an immediate short-term response causing a rapid GH release. CJC-1295, on the contrary, exercises a long-term influence by enhancing GH secretion over an extended duration and helps maintain standard physiological secretion patterns of GH. Having a half-life of just 2 hours, Ipamorelin is cleared more rapidly from the body. Keeping in view the pharmacokinetics of the two peptides, researchers effectively use them in a combination that will ensure a rapid response (attributed to Ipamorelin) and long-lasting effects (owing to CJC-1295).